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2017, br. 37, str. 5-9
jezik rada: engleski
vrsta rada: istraživanja
doi:10.5937/leksir1737005S


Antioxidant and antineurodegenerative properties of st. John's-wort dry extract
(naslov ne postoji na srpskom)
aInstitut za proučavanje lekovitog bilja 'Dr JosiPančić', Beograd
bUniverzitet u Beogradu, Biološki fakultet, Institut za botaniku i botanička bašta "JEVREMOVAC"

e-adresa: ksavikin@mocbilja.rs

Projekat

Tradicionalni i novi proizvodi od plodova gajenih i samoniklih vrsta voćaka i vinove loze i nus-produkata u preradi, sa posebnim osvrtom na autohtone sorte: hemijska karakterizacija i biološki profil (MPNTR - 46013)
Mikromorfološka, fitohemijska i molekularna istraživanja biljaka - sistematski, ekološki i primenljivi aspekti (MPNTR - 173029)

Sažetak

(ne postoji na srpskom)
Different biological activities of Hypericum perforatum L. dry extract was tested in this study. Antioxidant activity was evaluated by four different assays. Antineurodegenerative activity was tested using acetylcholinesterase (AChE) and tyrosinase inhibitory activity assays. In all four antioxidant assays, concentration dependent manner was noticed in the activity of tested extract. The most active was the highest applied concentration (500 µg/ml). In DPPH test, extract applied in concentration of 200 µg/ml showed similar or higher radical scavenging activity compared to the concentration of 100 µg/ml applied for standard substances BHA and BHT. The lowest antioxidant activity for the extract was detected in ABTS test. All applied concentrations of dry extract were significantly more potent than vitamin C in β-carotene test. Moreover, the extract reached 40.31 and 45.56% of the inhibition in AChE and TYR assays, respectively. In both cases, the most active concentration of the extract was 200 µg/ml.

Ključne reči

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