članak: 1 od 1  
Acta chirurgica iugoslavica
2006, vol. 53, br. 1, str. 57-62
jezik rada: srpski
stručni članak
doi:10.2298/ACI0601057G

Hirurške metode lečenja filodnih tumora dojke - prikaz 319 slučajeva
aUniverzitet u Beogradu, Medicinski fakultet, KBC 'Bežanijska kosa'
bUniverzitet u Beogradu, Medicinski fakultet, Institut za patološku anatomiju
cUniverzitet u Beogradu, Medicinski fakultet, Institut za onkologiju i radiologiju Srbije

Sažetak

Filodni tumori (FT) predstavljaju fibroepitelne tumore koji nastaju od fibroznog vezivnog tkiva terminalne duktulo-lobularne jedinice (TDLU) dojke. Oni čine 1% svih tumora dojke. Biološki i patohistološki se klasifikuju kao benigni, granični (borderline) i maligni. Neadekvatna hirurška ekscizija tumora može biti uzrok nastanka recidiva. Maligna forma FT metastazira hematogeno, najčešće u pluća. Nema jedinstvenog stava u hirurškom lečenju FT. Metode: Izvršena je analiza histopatoloških nalaza 319 FT dojke operativno odstranjenih na Odeljenju službe hirurgije Instituta za onkologiju i radiologiju Srbije u periodu 1.1.1985. do 31.12.1994 godine. Retrospektivno je izvršena analiza hirurškog lečenja 84 bolesnice zbog FT dojke (69 benignih, 4 bordeline i 11 malignih) i praćena njihova sudbina tokom 5 godina. Rezultati: Lokalni recidiv sve tri HP forme FT je verifikovan u 17 bolesnica (20,2%) (14 benignih, 2 borderline i 1 maligni FT), pulmonalne metastaze u 6 bolesnica (7,1%) sa malignim FT. DFI iznosio je za recidiv 21,3 meseca a pulmonalne metastaze 25,1 mesec. U 5- god. praćenju DFS (svi HP tipovi FT) iznosio je 71% (p=0,7104). Zaključak: S obzirom na biološko ponašanje optimalni hirurški pristup je široka tumorektomija za benigne i borderline FT i simplex mastektomija za maligne FT i voluminozne benigne i borderline u odnosu na veličinu dojke. Aksilarna disekcija je nepotrebna s obzirom da je limfogena diseminacija izuzetno retka.

Ključne reči

filodni tumor; tumor dojka

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