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Vojnosanitetski pregled 2002, vol. 59, br. 3, str. 317-324
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Multiorganska tuberkuloza
Vojnomedicinska akademija
SažetakTuberkuloza je neobična infektivna bolest jer latentni period, između infekcije i pojave bolesti, može trajati nedeljama, mesecima ili godinama kao u slučaju sekundarne tuberkuloze. Tuberkuloza drugih organa, bez plućne, je opisivana oduvek, ali nije bila prepoznata kao tuberkuloza i nazivana je mnogim imenima. Ekstrapulmonalna tuberkuloza je dobila na značaju jer ima sve većeg udela u novootkrivenim slučajevima. Multipla ekstrapulmonalna lokalizacija nije tako često prikazivana, dok se opisi na jednom organu često sreću. Pojava ekstrapulmonalne tuberkuloze raste sa godinama starosti, tako da često postoji specifična veza između doba bolesnika i lokalizacije tuberkuloze. Ekstrapulmonalna tuberkuloza se javlja na disajnim organima, van pluća, kao genitourinarna, centralnog nervnog sistema, abdominalna, kao tuberkuloza kostiju i zglobova, kože, perikarda i endokrinih žlezda. Povod ovom prikazu je namera da se analizuju kliničke, morfološke i laboratorijske karakteristike, dijagnoza i ishod bolesti kod bolesnika sa multiorganskom tuberkulozom u nastojanju da se objasne faktori koji doprinose donošenju odluka pri ovakvoj formi bolesti. Prikazali smo najnovija otkrića o patogenezi, kliničkoj slici, kao i efektima citokina, produkovanih od strane T limfocita, kao i ćelijske populacije na antimikobakterijske imunske odbrambene mehanizme i osetljivost prema tuberkulozi. Mortalitet od ove bolesti je visok i terapiju treba započeti što ranije, čak i u slučaju sumnje na tuberkulozu.
Ključne reči
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Reference
|
|
  
|
*** (1993) From the Centers for Disease Control and Prevention: Initial therapy for tuberculosis in the era of multidrug resistance: Recommendations of the Advisory Council for the Elimination of Tuberculosis. JAMA, 270(6): 694-8
|
|
|
*** (1998) Prevention and treatment of tuberculosis among patients infected with human immunodeficiency virus: Principles of therapy and revised recommendations. Centers for Disease Control and Prevention. MMWR Recomm Rep, 47(RR-20): 1-58
|
|
|
Addison, N.V. (1983) Abdominal tuberculosis: A disease revived. Ann R Coll Surg Engl, 65(2): 105-11
|
|
|
Bastani, B., Shariatzadeh, M.R., Dehdashti, F. (1985) Tuberculous peritonitis: Report of 30 cases and review of the literature. Q J Med, 56(221): 549-57
|
|
|
Bhansali, S.K. (1977) Abdominal tuberculosis. Experiences with 300 cases. Am J Gastroenterol, 67(4): 324-37
|
|
|
Christensen, W.I. (1974) Genitourinary tuberculosis: Review of 102 cases. Medicine (Baltimore), 53(5): 377-90
|
|
 2
|
Cohen, R., Muzaffar, S., Capellan, J., Azar, H., Chinikamwala, M. (1996) The validity of classic symptoms and chest radiographic configuration in predicting pulmonary tuberculosis. Chest, 109(2): 420-3
|
|
|
Davidson, P.T., le H.Q. (1992) Drug treatment of tuberculosis: 1992. Drugs, 43(5): 651-73
|
|
|
el-Solh A., Mylotte, J., Sherif, S., Serghani, J., Grant, B.J. (1997) Validity of a decision tree for predicting active pulmonary tuberculosis. Am J Respir Crit Care Med, 155(5): 1711-6
|
|
|
Farer, L.S., Lowell, A.M., Meador, M.P. (1979) Extrapulmonary tuberculosis in the United States. Am J Epidemiol, 109(2): 205-17
|
|
|
Gorse, G.J., Belshe, R.B. (1985) Male genital tuberculosis: A review of the literature with instructive case reports. Rev Infect Dis, 7(4): 511-24
|
|
|
Gow, J.G. (1971) Genito-urinary tuberculosis. A study of the disease in one unit over a period of 24 years. Ann R Coll Surg Engl, 49(1): 50-70
|
|
|
Haas, D.W., des Prez, R.M. (1994) Tuberculosis and acquired immunodeficiency syndrome: A historical perspective on recent developments. Am J Med, 96(5): 439-50
|
|
|
Israel, H.L., Gottlieb, J.E., Maddrey, W.C. (1992) Perspective: Preventive isoniazid therapy and the liver. Chest, 101(5): 1298-301
|
|
|
Jakubowski, A., Elwood, R.K., Enarson, D.A. (1988) Clinical features of abdominal tuberculosis. J Infect Dis, 158(4): 687-92
|
|
|
Joly, V., Hance, A.J., Yeni, P. (1993) Mycobacterium tuberculosis infection. Curr Opin Infect Dis, 6, str. 171-8
|
|
|
Kelestimur, F., Ozbakir, O., Saglam, A., Ozturk, F., Yucesoy, M. (1993) Acute adrenocortical failure due to tuberculosis. J Endocrinol Invest, 16(4): 281-4
|
|
1
|
Kim, J.H., Langston, A.A., Gallis, H.A. (1990) Miliary tuberculosis: Epidemiology, clinical manifestations, diagnosis, and outcome. Rev Infect Dis, 12(4): 583-90
|
|
|
Knight, R.K., Harrison, N.K. (1986) Tuberculosis of the nasopharynx misdiagnosed as Wegener's granulomatosis. Thorax, 41(3): 219-20
|
|
|
Knockaert, D.C., Vanneste, L.J., Vanneste, S.B., Bobbaers, H.J. (1992) Fever of unknown origin in the 1980s. An update of the diagnostic spectrum. Arch Intern Med, 152(1): 51-5
|
|
|
Lindell, M.M., Jing, B.S., Wallace, S. (1977) Laryngeal tuberculosis. Am J Roentgenol / AJR, 129(4): 677-80
|
|
|
Maartens, G., Willcox, P.A., Benatar, S.R. (1990) Miliary tuberculosis: Rapid diagnosis, hematologic abnormalities, and outcome in 109 treated adults. Am J Med, 89(3): 291-6
|
|
|
Morgan, S.H., Eastwood, J.B., Baker, L.R. (1990) Tuberculous interstitial nephritis: The tip of an iceberg?. Tubercle, 71(1): 5-6
|
|
1
|
Rieder, H.L., Snider, D.E., Cauthen, G.M. (1990) Extrapulmonary tuberculosis in the United States. Am Rev Respir Dis, 141(2): 347-51
|
|
|
Verdegem, T.D., Barnes, P.F., Vachon, L.A., Leedom, J.M., Overturf, G.D. (1988) Chest roentgenogram in pulmonary tuberculosis. New data on an old test. Chest, 94(2): 316-20
|
|
|
Young, L.S., Wormser, G.P. (1994) The resurgence of tuberculosis. Scand J Infect Dis Suppl, 93: 9-19
|
|
|
Yu, Y.L., Chow, W.H., Humphries, M.J., Wong, R.W., Gabriel, M. (1986) Cryptic miliary tuberculosis. Q J Med, 59(228): 421-8
|
|
|
|
|