članak: 1 od 1  
Vojnosanitetski pregled
2005, vol. 62, br. 7-8, str. 581-585
jezik rada: engleski
prikaz slučaja
doi:10.2298/VSP0508581L

Visoka doza streptokinaze u lečenju plućne embolije komplikovane kardiogenim šokom, respiratornim arestom i ventrikularnom fibrilacijom
aUniverzitet u Beogradu, Medicinski fakultet, Klinički centar Srbije
bUniverzitet u Beogradu, Medicinski fakultet, Institut za farmakologiju, kliničku farmakologiju i toksikologiju

e-adresa: Iratko@ptt.yu

Sažetak

Uvod. I pored napretka u profilaksi, dijagnostičkim modalitetima i terapijskim mogućnostima, plućna embolija je i dalje često nedijagnostikovan entitet sa letalnim ishodom. Kliničke manifestacije plućne embolije kreću se od masivne tromboembolije sa kardiogenim šokom do asimptomatske mikroembolije sa anatomski malim embolusima bez hemodinamskih, respiratornih i drugih komplikacija. Prikaz slučaja. Prikazan je bolesnik sa masivnom plućnom embolijom koja je bila komplikovana ventrikulskim fibrilacijom, respiratornim zastojem i kardiogenim šokom. Lečen je ukupnom dozom od 3 750 000 IJ streptokinaze datom intravenski tokom 8 sati. Nakon uspešne kardiopulomonalne reanimacije i primenjene trombolitičke terapije već 6 sati nakon prijema bolesnik je bio hemodinamski stabilan i bez kliničkih i elektrokardiografskih znakova insuficijencije desnog srca. Zaključak. Ovaj prikaz slučaja sugeriše da lečenje velikom dozom streptokinaze može biti korisno kod bolesnika sa masivnom plućnom embolijom komplikovanom kardiogenim šokom, što mora biti dokazano daljim randomizovanim studijama.

Ključne reči

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