članak: 1 od 1  
Vojnosanitetski pregled
2010, vol. 67, br. 5, str. 431-435
jezik rada: srpski
neklasifikovan
doi:10.2298/VSP1005431J

Marsupijalizacija i enukleacija keratocističnog odontogenog tumora uz primenu Karnojevog rastvora
aUniverzitet u Nišu, Medicinski fakultet, Stomatološka klinika
bInstitut za patologiju, Niš

Sažetak

Uvod. Keratocistični odontogeni tumori (KCOT) odnosno odontogene keratociste, agresivne su i ekspanzivne odontogene neoplazme sa velikim procentom recidiva (25-60%). Mali je broj publikacija o kombinaciji marsupijalizacije i enukleacije uz primenu Karnojevog rastvora u terapiji KCOT. Prikaz bolesnika. Kod bolesnice, stare 24 godine, u prvoj fazi urađena je marsupijalizacija KCOT, a u drugoj, posle šest meseci, enukleacija uz primenu Karnojevog rastvora. Izgubljeni senzibilitet donje usne uspostavio se posle tri meseca. Postoperativni defekt potpuno se ispunio posle sedam meseci. Ortopantomografski snimak posle godinu dana pokazao je prisustvo novostvorenog koštanog tkiva, dok se posle 7 godina vidi potpuno očuvana novoformirana kost mandibule i rekanalizacija mandibularnog kanala. Zaključak. Smatramo da smo ovom metodom imali uspeha u lečenju KCOT, zbog odsustva recidiva posle sedam godina. Ipak, potrebno je i dalje periodično praćenje bolesnika zbog mogućih kasnih recidiva.

Ključne reči

Reference

Aboul-hosn, C.S., Marí-Roig, A., Piulachs-Clapera, P., Juárez-Escalona, I., Monner-Diéguez, A., Díaz-Carandell, A., i dr. (2006) Primary intraosseous carcinoma and odontogenic cyst. Three new cases and review of the literature. Med Oral Patol Oral Cir Bucal, 11(1), str. 61-5
Barreto, D.C., Gomez, R.S., Bale, A.E., Boson, W.L., de Marco, L. (2000) PTCH gene mutations in odontogenic keratocysts. Journal of dental research, 79(6): 1418-22
Bataineh, A.B., al Qudah, M. (1998) Treatment of mandibular odontogenic keratocysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 86(1): 42-7
Binali, C., Ozkan, M., Umit, Z., Mustafa, G., Nesrin, G. (2008) Keratocystic odontogenic tumor invading the right maxillary sinus: A case report. Journal of Oral Science, 50(3): 345-9
Boyne, P.J., Hou, D., Moretta, C., Pritchard, T. (2005) The multifocal nature of odontogenic keratocysts. Journal of the California Dental Association, 33(12): 961-5
Brøndum, N., Jensen, V.J. (1991) Recurrence of keratocysts and decompression treatment: A long-term follow-up of forty-four cases. Oral surgery, oral medicine, and oral pathology, 72(3): 265-9
Cavalcante, R.B., Pereira, K.M.A., Nonaka, C.F.W., Nogueira, R.L.M., Souza, L.B. (2008) Immunohistochemical expression of MMPs 1, 7, and 26 in syndrome and nonsyndrome odontogenic keratocysts. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 106(1): 99-105
Dayal, P.K., Rawal, Y.B. (1997) Primary intraosseous carcinoma of the jaws originating in odontogenic cysts. Indian J Cancer, 34(1): 6-11
Diniz, M.G., Borges, E.R., Guimarães, A.L.S., Moreira, P.R., Brito, J.A.R., Gomez, M.V., de Marco, L., Gomez, R.S. (2009) PTCH1 isoforms in odontogenic keratocysts. Oral oncology, 45(3): 291-5
Eyre, J., Zakrzewska, J.M. (1985) The conservative management of large odontogenic keratocysts. British journal of oral & maxillofacial surgery, 23(3): 195-203
González-García, R., Sastre-Pérez, J., Nam-Cha, S.H., Muñoz-Guerra, M.F., Rodríguez-Campo, F.J., Naval-Gías, L. (2007) Primary intraosseous carcinomas of the jaws arising within an odontogenic cyst, ameloblastoma, and de novo: Report of new cases with reconstruction considerations. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 103(2): e29
Kolokythas, A., Fernandes, R.P., Pazoki, A., Ord, R.A. (2007) Odontogenic keratocyst: to decompress or not to decompress? A comparative study of decompression and enucleation versus resection/peripheral ostectomy. Journal of oral and maxillofacial surgery, 65(4): 640-4
Lo, M.L., Staibano, S., Pannone, G., Bucci, P., Nocini, P.F., Bucci, E., de Rosa, G. (1999) Expression of cell cycle and apoptosis-related proteins in sporadic odontogenic keratocysts and odontogenic keratocysts associated with the nevoid basal cell carcinoma syndrome. Journal of dental research, 78(7): 1345-53
Morgan, T.A., Burton, C.C., Qian, F. (2005) A retrospective review of treatment of the odontogenic keratocyst. Journal of oral and maxillofacial surgery, 63(5): 635-9
Petrović, V., Gavrić, M. (1994) Cysts of mandibule, face and neck. Belgrade: Science
Philipsen, H.P. (2005) Keratocystic odonogenic tumour. u: Barnes L, Eveson JW, Reichart P, Sidransky D. (ur.) World Health Organization classification of tumors: Pathology and genetics of head and neck tumors, Lyon: IARC Press, p. 306-7
Schmidt, B.L., Pogrel, M.A. (2001) The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts. J Oral Maxillofac Surg, 59(7): 720-5; discussion 726-7
Schultz, C.B., Pajarola, G.F., Gratz, K.W. (2005) Therapy and course of recurrent odontogenic keratocyst: A case report. Rivista mensile svizzera di odontologia e stomatologia / SSO, 115(6): 554-65
Stoelinga, P.J. (2001) Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg, 30(1): 14-25
Sun, L.S., Li, X.F., Li, T.J. (2008) PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. Journal of dental research, 87(6): 575-9
Thyne, G.M., Hunter, K.M. (1994) Primary reconstruction of the mandible with iliac bone and titanium implants following resection of a recurrent odontogenic keratocyst. New Zealand dental journal, 90(400): 56-9
Tolstunov, L., Treasure, T. (2008) Surgical treatment algorithm for odontogenic keratocyst: Combined treatment of odontogenic keratocyst and mandibular defect with marsupialization, enucleation, iliac crest bone graft, and dental implants. Journal of oral and maxillofacial surgery, 66(5): 1025-36
Voorsmit, R.A.CA. (1985) The incredible keratocyst: A new approach to treatment. Dtsch Zahnarzrtl Z, 40: 641-4
Young, C.A., Jones, S.R.M. (2005) Epitopes associated with mature spores not recognized on Kudoa thyrsites from recently infected Atlantic salmon smolts. Diseases of Aquatic Organisms, 63(2&3), 267-271
Zhao, Y., Wei, J., Wang, S. (2002) Treatment of odontogenic keratocysts: A follow-up of 255 Chinese patients. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 94(2): 151-6