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Vojnosanitetski pregled
2011, vol. 68, br. 8, str. 661-668
jezik rada: engleski
vrsta rada: izvorni naučni članak
doi:10.2298/VSP1108661S


Epidemiologija bolničkih infekcija/kolonizacija uzrokovanih Acinetobacter spp. u ratu i miru kod bolesnika iz šest hirurških klinika
aVojnomedicinska akademija
bUniverzitet u Novom Sadu, Medicinski fakultet, Institut za kardiovaskularne bolesti

e-adresa: pas@eunet.rs

Sažetak

Uvod/Cilj. U poslednjih par decenija Acinetobacter spp. postaje značajan uzročnik kolonizacija/infekcija kod hospitalizovanih bolesnika. Njegovo širenje dobilo je poseban značaj u vojnim bolnicama. Cilj ovog istraživanja bio je da se uporede rezultati epidemiološkog nadzora nad bolničkim kolonizacijama/infekcijama uzrokovanim ovom bakterijom dobijeni u periodu rata sa rezultatima dobijenim u periodu mira. Metode. Istraživanje je rađeno kao prospektivna studija incidencije kolonizovanih/inficiranih bolesnika Acinetobacter spp. Takođe, izvedene su dve 'ugnežđene' anamnestičke studije. Bolesnici sa infekcijom uzrokovanom Acinetobacter spp. (slučajevi) upoređeni su sa kolonizovanim bolesnicima (kontrole) istim uzročnikom u periodu rata i u periodu mira. Sveobuhvatni epidemiološki nadzor u cilju identifikacije ispitanika sproveden je u šest hirurških klinika Vojnomedicinske akademije. Rezultati. U periodu istraživanja registrovano je 166 bolesnika kod kojih je izolovan Acinetobacter spp. kao uzročnik kolonizacije ili infekcije. Uočeno je da su stopa kolonizacije/infekcije na svim posmatranim klinikama bile značajno više u periodu rata. Takođe, postojale su značajne razlike između ispitanika u periodu rata u odnosu na period mira. U ratnoj godini, ispitanici su češće bili muškog pola (p < 0,000), dok su u godinama mira ispitanici češće bolovali od neke hronične bolesti (p = 0,020), a i preživljavanje ispitanika bilo je značajno učestalije (p = 0,049). Rezistencija izolata Acinetobacter spp. na ciprofloksacin, imipenem i meropenem bila je značajno učestalija u periodu mira (p < 0,001). Zaključak. Ovo istraživanje obezbeđuje dodatne informacije o faktorima rizika od nastanka infekcija izazvanih Acinetobacter u kohorti hirurških bolesnika. Takođe, ovo istraživanje po prvi put ukazuje na značajne epidemiološke razlike između kolonizovanih/inficiranih bolesnika u periodu mira u odnosu na ratni period.

Ključne reči

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