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2014, vol. 71, br. 5, str. 506-509
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Sarkoidoza pleure
Sarcoidosis of the pleura: A case report
aKlinički centar Srbije, Klinika za pulmologiju, Beograd + Univerzitet u Beogradu, Medicinski fakultet bKlinički centar Srbije, Centar za radiologiju i magnetnu rezonancu, Beograd cKlinički centar Srbije, Klinika za pulmologiju, Beograd
e-adresa: draganajv@yahoo.com
Projekat: Kliničko epidemiološka istraživanja najčešćih neželjenih događaja tokom bolničkog lečenja (MPNTR - 175046)
Sažetak
Uvod. Zahvaćenost pleure je retka manifestacija sarkoidoze. Može se manifestovati kao pleuralni izliv, pneumotoraks, pleuralno zadebljanje, noduli, kao hidropneumotoraks, zarobljena pluća, hemotoraks ili hilotoraks. Učestalost pleuralnog izliva kod sarkoidoze kreće se od 0% do 5%, ali može biti i do 7,5%. Zahvaćenost pleure kod sarkoidoze javlja se kod < 3% bolesnika. Prikaz bolesnika. Prikazan je bolesnik, star 64 godine, sa hroničnom multiorganskom sarkoidozom. Bolesnik je razvio pleuralnu sarkoidozu sa masivnim pleuralnim izlivom nekoliko godina nakon postavljanja dijagnoze sarkoidoze. Definitivna dijagnoza sarkoidoznog pleuralnog izliva postavljena je na osnovu biopsije koja je pokazala nekazeifikovani granulom. Bolesnik je dobro reagovao na lečenje metotreksatom i metilprednisolonom, sa kompletnim povlačenjem pleuralnog izliva posle pet nedelja lečenja. Zaključak. Ovo je redak slučaj pleuralne zahvaćenosti sarkoidozom sa masivnim pleuralnim izlivom koji je dobro reagovao na lečenje.
Abstract
Introduction. Pleural involvement is an uncommon manifestation of sarcoidosis. It may manifest as pleural effusion, pneumothorax, pleural thickening and nodules, hydropneumothorax, trapped lung, hemothorax, or chylothorax. The incidence of pleural effusion with sarcoidosis ranges from 0% to 5% but has been reported to be as high as 7.5%. Pleural effusions complicate sarcoidosis in < 3% of patients. Case report. We reported a 64-year-old male patient with chronic multiorgan sarcoidosis. This patient developed pleural sarcoidosis with massive pleural effusion several years after the diagnosis of sarcoidosis. A definitive diagnosis of a sarcoid pleural effusion was based on a biopsy demonstrating noncaseating granuloma. The patient responded well to the treatment (methotrexate and methylprednisolone) with a complete withdrawal of pleural effusion following five weeks of the treatment beginning. Conclusion. The presented patient is a rare case of pleural involvement of sarcoidosis with massive effusion, who responded well to the treatment.
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Reference
|
|
 
|
Battesti, J.P., Azoulay, E. (2001) Atypical forms of sarcoidosis]. Formes atypiques de sarcoidose. Ann Med Interne, 152(1): 51-7
|
|
|
Beekman, J.F., Zimmert, S.M., Chun, B.K., i dr. (1976) Spectrum of pleural involvement in sarcoidosis. Arch Intern Med, 136: 323
|
|
|
Berte, S.J., Pfotenhauer, M.A. (1962) Massive pleural effusion in sarcoidosis. Am Rev Respir Dis, 86: 261-4
|
|
|
Chao, D.C., Hassenpflug, M., Sharma, O.P. (1995) Multiple lung masses, pneumothorax, and psychiatric symptoms in a 29-year-old African-American woman. Chest, 108(3): 871-3
|
|
|
Chusid, E.L., Siltzbach, L.E. (1974) Sarcoidosis of the pleura. Ann Intern Med, 81: 190
|
|
|
Claiborne, R.A., Kerby, G.R. (1990) Pleural sarcoidosis with massive effusion and lung entrapment. Kans Med, 91(4): 103-5
|
|
1
|
Cohen, M., Sahn, S.A. (2001) Resolution of pleural effusions. Chest, 119(5): 1547-62
|
|
|
Everett, E.D., Overholt, E.L. (1968) Sarcoidosis and pleural effusion. Milit Med, 133(9): 731-3
|
|
|
Gardiner, I.T., Uff, J.S. (1978) Acute pleurisy in sarcoidosis. Thorax, 33(1): 124-7
|
|
|
Gordonson, J., Trachtenberg, S., Sargent, E.N. (1973) Superior vena cava obstruction due to sarcoidosis. Chest, 63(2): 292-3
|
|
|
Heidecker, J.T., Judson, M.A. (2003) Pleural effusion caused by trapped lung. South Med J, 96(5): 510-1
|
|
|
Huggins, J.T., Doelken, P., Sahn, S.A., King, L., Judson, M.A. (2006) Pleural effusions in a series of 181 outpatients with sarcoidosis. Chest, 129(6): 1599-604
|
|
|
Ilan, Y., Ben-Yehuda, A., Breuer, R. (1994) Pleural effusion: the presenting radiological manifestation of sarcoidosis. Isr J Med Sci, 30(7): 535-6
|
|
|
Johnson, N.M., Martin, N.D., McNicol, M.W. (1980) Sarcoidosis presenting with pleurisy and bilateral pleural effusions. Postgrad Med J, 56(654): 266-7
|
|
|
Kostina, Z.I., Ivanovskii, V.B., Voloshko, I.V., Kol´nikova, O.V., Khorovskaia, L.A. (1992) Diagnosis and treatment of pleural lesions in sarcoidosis of the respiratory organs. Probl Tuberk, [in Russian]
|
|
|
Kovnat, P.J., Donohoe, R.F. (1965) Sarcoidosis involving the pleura. Ann Intern Med, 62: 120-4
|
|
|
Loughney, E., Higgins, B.G. (1997) Pleural sarcoidosis: a rare presentation. Thorax, 52(2): 200-1
|
|
|
Lynch, J., Ma, Y., Koss, M., White, E. (2007) Pulmonary Sarcoidosis. Semin Respir Crit Care Med, 28(1): 053-074
|
|
|
Nicholls, A.J., Friend, J.A., Legge, J.S. (1980) Sarcoid pleural effusion: three cases and review of the literature. Thorax, 35(4): 277-81
|
|
|
Poe, R.H. (1978) Middle-lobe atelectasis due to sarcoidosis with pleural effusion. N Y State J Med, 78(13): 2095-7
|
|
|
Rockoff, S.D., Rohatgi, P.K. (1985) Unusual manifestations of thoracic sarcoidosis. AJR Am J Roentgenol, 144(3): 513-28
|
|
|
Salazar, A., Mañá, J., Corbella, X., Vidaller, A. (1994) Sarcoid pleural effusion: a report of two cases. Sarcoidosis, 11(2): 135-7
|
|
|
Selroos, O. (1966) Exudative pleurisy and sarcoidosis. Br J Dis Chest, 60: 191
|
|
|
Sharma, O.P., Gordonson, J. (1975) Pleural effusion in sarcoidosis: a report of six cases. Thorax, 30(1): 95-101
|
|
|
Soskel, N., Sharma, O.P. (1992) Pleural Involvement in Sarcoidosis: Case Presentation and Detailed Review of the Literature. Semin Respir Med, 13(06): 492-514
|
|
|
Soskel, N.T., Sharma, O.P. (2000) Pleural involvement in sarcoidosis. Curr Opin Pulm Med, 6(5): 455-68
|
|
|
Tommasini, A., di Vittorio, G., Facchinetti, F., Festi, G., Schito, V., Cipriani, A. (1994) Pleural effusion in sarcoidosis: a case report. Sarcoidosis, 11(2): 138-40
|
|
|
Tudela, P., Haro, M., Marti, S., Roig, J. (1992) Eosinophilic pleuritis as the presenting form of sarcoidosis]. Pleuritis eosinofilica como forma de presentacion en la sarcoidosis. Med Clin (Barc), 99(14): 558
|
|
|
Warshawsky, M.E., Shanies, H.M., Rozo, A. (1997) Sarcoidosis involving the thyroid and pleura. Sarcoidosis Vasc Diffuse Lung Dis, 14(2): 165-8
|
|
|
Werf, V.T.S., Vennik, P.H.W. (1997) Rare presentation or lead time bias in pleural sarcoidosis?. Thorax, 52: 752
|
|
|
Wilen, S.B., Rabinowitz, J.G., Ulreich, S., Lyons, H.A. (1974) Pleural involvement in sarcoidosis. Am J Med, 57(2): 200-9
|
|
|
|
|