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Medicinski časopis
2016, vol. 50, br. 2, str. 63-71
jezik rada: srpski
vrsta rada: prikaz
doi:10.5937/mckg50-11631


Prednosti i mane urgentne postkoitalne kontracepcije
aKatedra za farmaciju, Medicinski fakultet, Univerzitet u Novom Sadu
bAgencija za ljekove i medicinska sredstva Crne Gore, Podgorica, Crna Gora
cUniverzitet u Beogradu, Medicinski fakultet, GAK 'Narodni front'
dKlinika za ginekologiju i akušerstvo, Klinički centar Srbije, Beograd
eUniverzitet u Novom Sadu, Medicinski fakultet

e-adresa: svetlana.golocorbin-kon@mf.uns.ac.rs

Projekat

Interakcije ksenobiotika i uticaj na sisteme u biomedicini (MPNTR - 41012)

Sažetak

Urgentna postkoitalna kontracepcija (UPK), takođe poznata kao 'urgentna kontracepcija' i kao 'tableta za jutro posle'jednostavan je način da se prevenira začeće, a u većini zemalja nabavlja se bez recepta. Primenom UPK može se sprečiti neželjena trudnoća ako izostane efekat primenjene zaštite, ako nije korišćena nijedna metoda zaštite ili ako je došlo do silovanja. Trenutno raspoloživa sredstva i metode za zaštitu od neželjene trudnoće podrazumevaju peroralnu primenu kombinacije estrogen-progestina (etinilestradiol sa levonorgestrelom), primenu samo progestina (levonorgestrel), korišćenje peroralnog ulipristal acetata, antiprogestin sintetičkog steroida mifepristona (RU-486), samog estrogena (visoke doze etiniletsradiola) i bakarne T spirale. UPK tablete su mnogo dostupnije nego bakarne T spirale, smanjuju mogućnost nastanka trudnoće posle jednog nezaštićenog odnosa za najmanje 50%. Bakarna T spirala je najefikasniji oblik UPK sa izostankom dejstva manjim od 1%. UPK je jednostavna za primenu i pravovremena upotreba smanjuje mogućnost nastanka neželjene trudnoće, pri čemu trudnoća koja eventualno već postoji neće biti ugrožena. UPK ne mogu da koriste žene koje ne smeju da uzimaju peroralne kontraceptive, ne štiti od seksualno prenosivih bolesti i ne može se koristiti kao redovan metod kontracepcije. UPK treba upotrebiti što pre nakon nezaštićenog odnosa, jer joj se vremenom smanjuje efikasnost. Mogu se javiti neželjene nuspojave poput muke i povraćanja, odlaganja pojave menstruacije, neregularnog vaginalnog krvarenja, bola u abdomenu, glavobolje, vrtoglavice, koje najčešće nestaju tokom naredna 24 časa. Takođe su retke nuspojave nakon upotrebe bakarne T spirale, ali ako se jave onda su u pitanju poremećaj menstrualnog krvarenja i povećano oticanje krvi.

Ključne reči

kontracepcija; postkoitalna; farmaceutski preparati; neželjena dejstva u vezi sa lekom i neželjene reakcije

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