članak: 1 od 1  
Journal of the Serbian Chemical Society
2009, vol. 74, br. 2, str. 141-154
jezik rada: engleski
izvorni naučni članak
doi:10.2298/JSC0902141S

Sinteza, koordinacija i biološki aspekti organokalaj(IV) derivata 4-[(2,4-dinitrofenil)amino]-4-okso-2-butenske akrilne kiseline i 2-{[(2,4-dinitrofenil)amino]karbonil} benzoeve kiseline
aDepartment of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan
bDepartment of Chemistry, GC University, Faisalabad, Pakistan

e-adresa: drsa54@yahoo.com

Sažetak

Sintetisana je nova serija organokalaj(IV) kompleksa anilinskih derivata, R2SnL2 i R3SnL [gde je R = Me, n-Bu, Ph, n-Oct], reakcijom HL1 i HL2 sa odgovarajućim organo- kalajnim halogenidima ili oksidima. Dati su eksperimentalni detalji za dobijanje i karakterizaciju (uključujući elementalnu analizu, IR i multinuklearnu NMR (1H, 13C i 119Sn spektri u CDCl3) i EI masene spektre) obe serije. Vezujuća mesta liganada su identifikovana pomoću FTIR spektroskopskih merenja, i nađeno je da u svim slučajevima organokalajni(IV) deo reaguje sa kiseonikom COO- grupe gradeći nove komplekse. U diorganokalajnim kompleksima u čvrstom stanju COO- grupa je koordinovana za organokalaj(IV) centre kao bidentat. 119Sn-NMR podaci i nJ(13C-119/117Sn) konstanta kuplovanja u skladu su sa tetraedarskom koordinacionom geometrijom organokalajnih kompleksa u rastvaračima koji nemaju koordinaciona svojstva. Takođe je objavljena biološka aktivnost ovih jedinjenja (antibakterijska, antifungalna, insekticidna, citotoksičnost i protiv protozoa iz roda Leishmania).

Ključne reči

organotin(IV) carboxylates; IR; multinuclear NMR (1H; 13C and 119Sn); mass spectrometry; biological activity

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