članak: 1 od 1  
Archives of Biological Sciences
2011, vol. 63, br. 3, str. 579-587
jezik rada: engleski
naučni članak
doi:10.2298/ABS1103579L

Vasopressin modulates hypothalamo-pituitary activity by paracrine action during acute and chronic immobilization stress in rats
(naslov ne postoji na srpskom)
Univerzitet u Beogradu, Biološki fakultet


Projekat Ministarstva nauke Republike Srbije, br. 173023

Sažetak

(ne postoji na srpskom)
The aim of the study was to examine changes in corticotropin releasing hormone (CRH), vasopressin (VP), adrenocorticotropin (ACTH) as well as VP3 receptor protein concentration in the hypothalamus and the pituitary of rats exposed to acute (3 h) and chronically repeated (3 h daily for 7 days) immobilization stress. Our results show that, unlike the increase in ACTH, there were no changes in serum VP despite the significant changes in this hormone and its receptor concentrations in the hypothalamus and pituitary (HP). This suggests that VP regulates HP activity by predominantly acting in a paracrine manner under the examined stress condition.

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