članak: 1 od 1  
Acta infectologica Iugoslavica
2002, vol. 7, br. 3, str. 23-27
jezik rada: srpski
originalan članak
Serološka dijagnoza lajmske bolesti
Univerzitet u Beogradu, Medicinski fakultet, Klinički centar Srbije

Sažetak

Dijagnoza lajmske borelioze zasniva se na karakterističnom kliničkom nalazu uz anamnestički podatak o kontaktu sa inficiranim krpeljom roda Ixodes. Kao i kod drugih infekcija spirohetama i u toku lajmske borelioze razlikuju se rani, intermedijarni i kasni stadijum. Rana lajmska bolest može biti neprepoznata ili proricati asimptomatski, dok intermedijarni i kasni stadijum mogu podsećati na druga oboljenja. Zbog toga je neophodna laboratorijska potvrda ove infekcije. Laboratorijski testovi podrazumevaju one kojima se dokazuje prouzrokovač B. burgdorferi, njeni antigeni ili nukleinska kiselina (PCR), i serološke testove kojima se dokazuje imunski odgovor, i koji se češće koriste. Serološki testovi mogu biti tzv. skrining testovi (HA, IFT i ELISA) i potvrdni testovi posebno za IgM i IgG (Western blot). Negativna serologija ne isključuje ranu boreliozu, a pozitivna nije etiološki dokaz sadašnjeg oboljenja već može biti i odraz ranije infekcije. Rezultati seroloških testova imaju značaja u postavljanju dijagnoze ali ne mogu sami za sebe biti presudni.

Ključne reči

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