članak: 1 od 1  
Acta chirurgica iugoslavica
2011, vol. 58, br. 1, str. 33-38
jezik rada: engleski
stručni članak
doi:10.2298/ACI1101033S

Potencijalna uloga scintigrafske procene relativne perfuzije jetre u dijagnostici i terapiji karcinoma jetre
aUniverzitet u Beogradu, Medicinski fakultet, Klinički centar Srbije
bInstitute for Nuclear Medicine, Clinical Center of Serbia, Belgrade
cGastroenterology Department, Clinical Center Podgorica, Podgorica, Montenegro
dGastroenterology Department, Clinical Center Kragujevac, Kragujevac


Projekat Ministarstva nauke Republike Srbije, br. M 145033

Sažetak

Cilj: Cilj rada je procena potencijalne uloge scintigrafske procene perfuzije jetre u dijagnozi i izboru lečenja karcinoma jetre. Bolesnici i metode: Hepatički perfuzioni indeks je određen posle dinamske scintigrafije u 126 pacijenata. Rezultati: U kontrolnoj grupi vrednosti se ne razlikuju od onih u pacijenata sa benignim tumorima (p<0.05). Ipak, u hepatocelularnom karcinomu i metastazama različitih tumora u jetri, HPI vrednosti su značajno snižene u poređenju sa kontrolnom grupom i bolesnicima sa benignim tumorima (p<0.01), ali se ne razlikuju međusobno (p>0.05). Vrednosti su posebno niske u bolesnika sa malignim bolestima jetre udruženim sa vaskularnim poremećajima u portnom sistemu. Zaključak: HRA se može jednostavno uraditi u toku različitih metoda nuklearne medicine. Dodatno, može biti korisna metoda za procenu hemodinamskih poremećaja u portnom sistemu različitog stepena, za diferencijalnu dijagnozu benignih od malignih tumora, kao i za procenu perfuzije tkiva jetre i tumora, što može biti korisno u donošenju odluke za preduzimanje intrarterijske (radionuklidne ili hemo) terapije.

Ključne reči

hepatična radionukleidna angiogafija; tumor jetre; perfuzija

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