članak: 1 od 1  
Hemijska industrija
2011, vol. 65, br. 5, str. 575-581
jezik rada: srpski
naučni članak
doi:10.2298/HEMIND110408039M

Antifungalna aktivnost odabranih policikličnih aromatičnih ugljovodonika prema ligninolitičkim gljivama
Prirodno-matematički fakultet, Univerzitet u Sarajevu, Sarajevo, Bosna i Hercegovina

e-adresa: m_memic@yahoo.com

Sažetak

Nova pravila o odlaganju pepela u državama Evropske Unije ograničavaju mogućnost bilo kakvog spaljivanja staroga drveta koje je zaštitom sa kreozotnim uljem kontaminirano (IRG/95-50042). Kreozotno ulje je jedan od glavnih izvora policikličnih aromatičnih ugljovodonika (PAH), koji su akutno i hronično toksični kako za ljude tako i za druge ekosisteme a pri dugoj izloženosti neki od njih su kancerogeni. Među opcijama koje puno obećavaju spada biorazgradnja pomoću mikroorganizama, a u posljednje vrijeme pomoću gljiva. Ligninolitičke gljive su, najverovatnije, jedina grupa organizama koja može potpuno mineralizovati lignin. U ovom radu je testirana antifungalna aktivnost 12 PAH-ova prema gljivi bijele truleži Hypoxylon fragiforme i gljivi smeđe truleži, Coniophora puteana koja se može povezati sa sposobnošću ovih gljiva da razgrađuju PAH-ove. Pokazalo se da antifungalna aktivnost testiranih PAH-ova koncentracije 2,5 mmol/L zavisi od osobina testiranih PAH-ova i nije izražena u toj mjeri da spriječi rast gljiva. Uticaj PAH-ova na testirane gljive u direktnoj je vezi sa molekulskom masom, rastvorljivosti u vodi, vrijednosti log Kow, jonizacionim potencijalom i Henrijevom konstantom kao i načinom kondezacije benzenovih prstenova. Veću antifungalnu aktivnost prema gljivama pokazali su prije svega PAH-ovi sa pet i četiri prstena u odnosu na PAH-ove sa manjim brojem prstenova.

Ključne reči

Reference

*** NIST chemistry webbook. http://webbook.nist.gov//chemistry/name-ser.html
Alexander, M. (1994) Biodegradation and bioremediation. New York-San Diego, itd: Academic Press
Aust, S.D. (1990) Degradation of environmental pollutants byPhanerochaete chrysosporium. Microbial Ecology, 20(1): 197-209
Bazel, L., Hadar, Y., Fu, P.P., Freemen, J.P., Cerniglia, C.E. (1996) Initial oxidation products in the metabolism of pyrene, anthracene, fluorene, and dibenzotiophene by the white rot fungus Pleurotus ostreatus. Appl. Microbiol. Biotechnol, 62, 2554-2559
Bogan, B.W., Lamar, R.T. (1995) One-electron oxidation in the degradation of creosote polycyclic aromatic hydrocarbons by Phanerochaete chrysosporium. Applied and environmental microbiology, 61(7): 2631-5
Bogan, B.W., Lamar, R.T., Hammel, K.E. (1996) Fluorene Oxidation In Vivo by Phanerochaete chrysosporium and In Vitro during Manganese Peroxidase-Dependent Lipid Peroxidation. Applied and environmental microbiology, 62(5): 1788-92
Bumpus, J.A., Tien, M., Wright, D., Aust, S.D. (1985) Oxidation of persistent environmental pollutants by a white rot fungus. Science, 228(4706): 1434-6
Cavalieri, E., Rogan, E. (1985) Role of radical cations in aromatic hydrocarbon carcinogenesis. Environmental Health Perspectives, 64: 69-84
Cerniglia, C.E. (1997) Fungal metabolism of polycyclic aromatic hydrocarbons: Past, present and future applications in bioremediation. J Ind. Microbiol, 19. 324-333
Cerniglia, C.E. (1997) Fungal metabolism of polycyclic aromatic hydrocarbons: Past, present and future applications in bioremediation. J Ind. Microbiol, 19. 324-333
Collins, J.F., Brown, J.P., Dawson, S.V., Marty, M.A. (1991) Risk assessment for benzo[a]pyrene. Regulatory toxicology and pharmacology, 13(2): 170-84
Collins, P.J., Kotterman, M., Field, J.A., Dobson, A. (1996) Oxidation of Anthracene and Benzo[a]pyrene by Laccases from Trametes versicolor. Applied and environmental microbiology, 62(12): 4563-7
Dabestani, R., Ivanov, N. (1999) Invited review: A compilation of physical, spectroscopic and photo physical properties of polycyclic aromatic hydrocarbons. Photochem. Photobiol, 70, str. 10-34
Dey, S., Maiti, T., Bhattacharyya, B. (1991) Lignin peroxidase production by a brown-rot fungus Polyporus ostreiformis. Journal of Fermentation and Bioengineering, 72(5): 402-404
Dey, S., Maiti, T.K., Bhattacharyya, B.C. (1994) Production of some extracellular enzymes by a lignin peroxidase-producing brown rot fungus, Polyporus ostreiformis, and its comparative abilities for lignin degradation and dye decolorization. Applied and environmental microbiology, 60(11): 4216-8
Hammel, K.E., Green, B., Gai, W.Z. (1991) Ring fission of anthracene by a eukaryote. Proceedings of the National Academy of Sciences of the United States of America, 88(23): 10605-8
Hammel, K.E., Kalyanaraman, B., Kirk, T.K. (1986) Oxidation of polycyclic aromatic hydrocarbons and dibenzo[p]-dioxins by Phanerochaete chrysosporium ligninase. Journal of biological chemistry, 261(36): 16948-52
Hatakka, A. (1994) Biodegradation of lignin. u: Hofrichter M., Steinbüchel A. (ur.) Biopolymers: Lignin, humic substances and coal, Wiley-VCH, str. 129-180
Howsam, M., Jones, K.C. (1998) Sources of PAHs in the environment. u: Neilson A.H. (ur.) Anthropogenic compounds: PAHs and related compounds, Springer, str. 137-174
Jin, L., Schultz, T.P., Nicolas, D.D. (1990) Structural characterization of brown-rotted lignin. Holzforschung, 44: 132-138
Kirk, T.K., Connors, W.J., Zeikus, J.G. (1976) Requirement of growth substrate during lignin degradation by two wood rotting fungi. Appl. Environ. Micrbiol, 32, str. 192-194
Kotterman, M.J.J., Heessels, E., Jong, E., Field, J.A. (1994) The physiology of anthracene biodegradation by the white-rot fungus Bjerkandera sp. strain BOS55. Applied Microbiology and Biotechnology, 42(1): 179-186
Lundstedt, S. (2003) Analysis of PAHs and their transformation products in contaminated soil and remedial processes. Department of Chemistry, Environmental Chemistry, Umeä University
Mackay, D., Shiu, W.Y., Ma, K.C. (1992) Illustrated handbook of physical-chemical properties and environmental fate for organic chemicals: Polynuclear aromatic hydrocarbons, polychlorinated dioxins and dibenzofurans. Michigen: Lewis Publishers
Micales, J.A., Highley, T.L. (1988) Some physiological characteristics of a nondegradative strain of Poria (=Postia) plancenta. Stockholm: Int. Res. Group on Wood Pres, Doc. br. IRG/WP/1341
Mueller, J.G., Champan, P.J., Pritchard, P.H. (1989) Creosote-contaminated sites. Their potential for bioremediation. Environmental Science & Technology, 23(10): 1197-1201
Park, K.S., Sims, R.C., Dupont, R., Doucette, W.J., Matthews, J.E. (1990) Fate of PAH compounds in two soil types: Influence of volatilization, abiotic loss and biological activity. Environmental Toxicology and Chemistry, 9(2): 187-195
Raspor, P., Smole, M.S., Podjavoršek, J., Pohleven, F., Gogala, N., Nekrep, V.F., Rogelj, I., Hacin, J. (1995) ZIM - Zbirka industrijskih mikroorganizmov. Ljubljana: Biotehniška fakulteta, Katalog biokultur
Score, A.J., Palfreyman, J.W., White, N.A. (1997) Extracellular phenoloxidase and peroxidase enzyme production during interspecific fungal interactions. International Biodeterioration and Biodegradation, 39(2-3): 225
Semple, K.T., Morriss, A.W.J., Paton, G.I. (2003) Bioavailability of hydrophobic organic contaminants in soils: fundamental concepts and techniques for analysis. European Journal of Soil Science, 54(4): 809-818
Wild, S.R., Jones, K.C. (1995) Polynuclear aromatic hydrocarbons in the United Kingdom environment: A preliminary source inventory and budget. Environmental Pollution, 88(1): 91-108
Wood, P.M. (1994) Pathways for production of Fenton's reagent by wood-rotting fungi. FEMS Microbiology Reviews, 13(2-3): 313-320