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Srpski arhiv za celokupno lekarstvo
2013, vol. 141, br. 1-2, str. 122-126
jezik rada: engleski
vrsta rada: prikaz
doi:10.2298/SARH1302122R


Celijačna bolest
Medicinski fakultet, Beograd + Univerzitetska dečja klinika, Beograd

e-adresa: n.radlovic@beotel.net

Sažetak

Celijačna bolest je multisistemsko autoimunsko oboljenje izazvano glutenom pšenice, raži i ječma. Odlikuju je poligenska predispozicija, visoka prevalencija (1%), veoma heterogena ekspresija i česta udruženost sa drugim autoimunskim oboljenjima, selektivnim deficitom IgA i Daunovim (Down), Tarnerovim (Turner) i Vilijemsovim (Williams) sindromom. Osnovu bolesti i ključni nalaz u njenoj dijagnostici čini simptomatsko ili asimptomatsko zapaljenje sluzokože tankog creva koje se povlači na dijeti bez glutena. Otuda i suštinu terapije čini eliminaciona dijeta, te ovaj poremećaj, ukoliko se blagovremeno prepozna i na odgovarajući način leči, odlikuje i izvanredna prognoza.

Ključne reči

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