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Glasnik Instituta za štitastu žlezdu i metabolizam "Zlatibor"
2001, vol. 5, br. 2, str. 28-39
jezik rada: srpski
vrsta rada: neklasifikovan

Subklinički hipotiroidizam
Institut za endokrinologiju, dijabetes i bolesti metabolizma, Beograd

Sažetak

Subklinički hipotiroidizam obično se definiše laboratorijskim parametrima - nalazom povišene koncentracije TSH u serumu uz normalne vrednosti tiroidnih hormona. Pošto tiroidna funkcija utiče na većinu tkiva i organa, pacijenti često ispoljavaju blage i nespecifične smetnje koje se naknadno povezuju sa hipotiroidizmom, kada se dobije laboratorijski nalaz. Osnovno pitanje u ovom problemu je da li aktivno tragati za osobama sa subkliničkim hipotiroidizmom i da li lečiti ovakve osobe. Ako se obavi retestiranje u nekih osoba se kasnije i bez terapije nađu normalne vrednosti TSH. Današnji je stav da se odluka o lečenju zasniva na kliničkom nalazu, trajno povišenom TSH i povišenim vrednostima serumskih lipida. Aktivno traganje za obolelima ima opravdanje naročito ako se uz povišen TSH nadu tiroidna autoantitela.

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