članak: 1 od 1  
Nuclear Technology and Radiation Protection
2008, vol. 23, br. 2, str. 72-78
jezik rada: engleski
naučni članak
doi:10.2298/NTRP0802072A

Upotreba ekstrakta ruzmarinovog lista protiv zračenjem izazvanih hematoloških i biohemijskih promena u miševa
Radiation & Cancer Biology Laboratory, Department of Zoology, Rajasthan, India

e-adresa: garimasancheti@rediffmail.com

Sažetak

Rad predstavlja proučavanje modulatornih efekata na zračenjem izazvane hematološke i biohemijske promene kod švajcarskih belih miševa usled primene ekstrakta lista Rosmarinus officinalis. Faktor redukcije doze do 1,52 za ruzmarinov ekstrakt kao sredstvo protiv gama zračenja izračunat je iz LD50/30 vrednosti. Ruzmarinov ekstrakt unošen je oralno pet uzastopnih dana pre izlaganja zračenju. Hematološki i biohemijski parametri procenjivani su u intervalu od prvog do tridesetog dana po ozračivanju. Ukupan broj eritrocita i leukocita, vrednosti hemoglobina i hematokrita u eksperimentalnoj grupi bile su povišene u poređenju sa kontrolnom grupom miševa. Postupak ruzmarinovim ekstraktom povisio je redukovani sadržaj glutationa u jetri i krvi nasuprot zračenjem izazvanog slabljenja. Lečenje biljnim ekstraktom dovelo je do značajnog pada nivoa lipidne peroksidaze, ukazujući na ulogu ruzmarina u zaštiti od zračenjem izazvanog oštećenja membrane i ćelije. Rezultati proučavanja upućuje na efekte zaštite ruzmarinovim ekstraktom od zračenjem izazvanih hematoloških i biohemijskih promena u miševa.

Ključne reči

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