Balkan Journal of Stomatology
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2013, vol. 17, iss. 1, pp. 31-36
Effects of various rates of polyacrylic acid and fluoride on Streptococcus mutans and Actinomyces viscosus
aIstanbul University, Faculty of Dentistry Department of Operative Dentistry, Istanbul, Turkey
bYeditepe University, Faculty of Dentistry Department of Operative Dentistry, Istanbul, Turkey
Keywords: Polyacrylic Acid; Fluoride; Streptococcus mutans; Actinomyces viscosus
Glass ionomer cements have been shown to possess antimicrobial activity. Fluoride release from these materials and initial acidity have been reported with regard to this. The purpose of this study was to investigate antimicrobial effects of various concentrations of fluoride and polyacrylic acid mixtures and to evaluate whether or not fluoride is responsible for this antibacterial activity. The antimicrobial properties of various fluoride and polyacid mixtures were tested against Streptococcus mutans and Actinomyces viscosus. The fluoride and polyacid mixtures; 5%, 10% and 20% polyacrylic acid were mixed with 1.000 ppm, 2.500 ppm, 5.000 ppm, and 10.000 ppm F. The role of fluoride ions and low pH in the antibacterial activity were also studied by using agar diffusion assay method measuring inhibition zones of the mixtures. 6 samples were prepared for each experimental group. Kruskal-Wallis test (ANOVA) was performed for statistical analysis. The findings showed that there were significant differences between 0 ppm and 5.000 ppm F; 0 ppm and 10.000 ppm F; 1.000 ppm and 10.000 ppm F when fluorides were mixed with 5% or 10% or 20% polyacrylic acid to determine the inhibition of S. Mutans (p<0.02). For Actinomyces viscosus significant differences were found between 0 ppm and 10000 ppmF; 1000 ppm and 10000 ppm F when fluorides were mixed with 5% or 10% or 20% polyacrylic acid (p<0.004). It is concluded that not only fluoride was directly responsible for the antibacterial activity, but the low pH of the medium appeared to play even more important role.
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article language: English
document type: Original Paper
published in SCIndeks: 24/09/2013