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2017, vol. 23, br. 1, str. 9-14
Orofacial complaints and complications of chemotherapy
(naslov ne postoji na srpskom)
aUniversidade Federal de Juiz de Fora, Dentistry School, Juiz de Fora, Brazil
bFederal Federal de Juiz de Fora, Dentistry School, Juiz de Fora, Brazil
cUniversidade Federal de Juiz de Fora, Institute of Exact Sciences, Juiz de Fora, Brazil

(ne postoji na srpskom)
Background: Oral complications of chemotherapy are sometimes unnoticed and if not treated, they can compromise patients' health and quality of life. Methods: This study aimed to assess and characterize orofacial complaints and complications, and their impact on the oral-health-related quality of life in patients undergoing cancer chemotherapy. Results: We evaluated 28 patients with solid tumors undergoing chemotherapy, through a systematic orofacial evaluation. Eighteen patients (64.2%) developed oral complications during chemotherapy and xerostomia scored the highest incidence n = 14 (50%). About oral health data, gingival index revealed greater part of patients classified with moderate or severe gingival inflammation. The mean plaque index was 25.6%. The mean CPOD index was 15.48 and was worse in patients without oral complications. The patients presented higher plaque index and the oral health impact profile showed higher mean index in the patients group that developed oral complications. Conclusion: These data reinforce the crucial role of the dentist in the multidisciplinary team, with crucial support in the diagnosis of oral complications. Thus, a specific assistance and relieve of patient's complaints could impact positively on quality of life.
Al-Ansari, S., Zecha, J.A. E. M., Barasch, A., de Lange, J., Rozema, F.R., Raber-Durlacher, J.E. (2015) Oral Mucositis Induced By Anticancer Therapies. Current Oral Health Reports, 2(4): 202-211
Allareddy, V., Elangovan, S., Rampa, S., Shin, K., Nalliah, R.P., Allareddy, V. (2015) Presence of gingivitis and periodontitis significantly increases hospital charges in patients undergoing heart valve surgery. Journal of the Massachusetts Dental Society, 63(4): 10-6
Almeida, P.M., Wickerhauser, H. (1991) Critério ABA (Associação Brasileira de Anunciantes) e ABIPEME (Associação Brasileira dos Institutos de Pesquisa de mercado)
Barkokebas, A., Silva, I.H.M., de Andrade, S.C., Carvalho, A.A.T., Gueiros, L.A.M., Paiva, S.M., Leão, J.C. (2015) Impact of oral mucositis on oral-health-related quality of life of patients diagnosed with cancer. Journal of oral pathology & medicine, 44(9): 746-51
Berglund, E., Westerling, R., Lytsy, P. (2017) Social and health-related factors associated with refraining from seeking dental care: A cross-sectional population study. Community dentistry and oral epidemiology, 45(3): 258-265
Brennan, M.T., Elting, L.S., Spijkervet, F.K.L. (2010) Systematic reviews of oral complications from cancer therapies, Oral Care Study Group, MASCC/ISOO: methodology and quality of the literature. Supportive care in cancer, 18(8): 979-84
Chapple, I.L. C., Genco, R. (2013) Diabetes and periodontal diseases: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. Journal of Clinical Periodontology, 40: S106-S112
Cheng, K.K., Leung, S.F., Liang, R.H.S., Tai, J.W.M., Yeung, R.M.W., Thompson, D.R. (2010) Severe oral mucositis associated with cancer therapy: impact on oral functional status and quality of life. Supportive care in cancer, 18(11): 1477-85
Cooperstein, E., Gilbert, J., Epstein, J.B., Dietrich, M.S., Bond, S.M., Ridner, S.H., Wells, N., Cmelak, A., Murphy, B.A. (2012) Vanderbilt Head and Neck Symptom Survey version 2.0: report of the development and initial testing of a subscale for assessment of oral health. Head & neck, 34(6): 797-804
Coronado-Castellote, L., Jimenez-Soriano, Y. (2013) Clinical and microbiological diagnosis of oral candidiasis. Journal of Clinical and Experimental Dentistry, str. e279-86
Dholam, K.P., Dugad, J.A., Sadashiva, K.M. (2017) Impact of oral rehabilitation on patients with head and neck cancer: A study using the Liverpool Oral Rehabilitation Questionnaire and the Oral Health Impact Profile-14. Journal of prosthetic dentistry, 117(4): 559-562
el Bousaadani, A., Eljahd, L., Abada, R., Rouadi, S., Roubal, M., Mahtar, M. (2016) Actualités de la prévention et du traitement des mucites orales chez les enfants cancéreux : recommandations pratiques. Cancer/Radiothérapie, 20(3): 226-230
Epstein, J.B., Elad, S., Eliav, E., Jurevic, R., Benoliel, R. (2007) Orofacial pain in cancer: part II--clinical perspectives and management. Journal of dental research, 86(6): 506-18
Epstein, J.B., Thariat, J., Bensadoun, R., Barasch, A., Murphy, B.A., Kolnick, L., Popplewell, L., Maghami, E. (2012) Oral complications of cancer and cancer therapy. CA: A Cancer Journal for Clinicians, 62(6): 400-422
Epstein, J.B., Polsky, B. (1998) Oropharyngeal candidiasis: a review of its clinical spectrum and current therapies. Clinical Therapeutics, 20(1): 40-57
Eveson, J.W. (2008) Xerostomia. Periodontology 2000, 48(1): 85-91
Ewan, V.C., Sails, A.D., Walls, A.W. G., Rushton, S., Newton, J.L. (2015) Dental and Microbiological Risk Factors for Hospital-Acquired Pneumonia in Non-Ventilated Older Patients. PLoS One, 10(4): e0123622
Fox, P.C., Busch, K.A., Baum, B.J. (1987) Subjective reports of xerostomia and objective measures of salivary gland performance. Journal of the American Dental Association, 115(4): 581-584
Fulton, J.S., Middleton, G.J., McPhail, J.T. (2002) Management of oral complications. Seminars in oncology nursing, 18(1): 28-35
Gomes, S.G.F., Cury, A.A.del B., Garcia, R.C.M.R. (2011) Effect of hyposalivation on mastication and mandibular movements during speech. Brazilian Oral Research, 25(4): 351-356
Hayashi, H., Kobayashi, R., Suzuki, A., Yamada, Y., Ishida, M., Shakui, T., Kitagawa, J., Hayashi, H., Sugiyama, T., Takeuchi, H., Tsurumi, H., Itoh, Y. (2016) Preparation and clinical evaluation of a novel lozenge containing polaprezinc, a zinc-L-carnosine, for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy. Medical oncology (Northwood, London, England), 33(8): 91
Kapoor, V., Basur, S., Pandey, A. (2015) Chemotherapy and Oral Complications: The Most Neglected Side of Cancer. J Adv Med Dent Scie Res., 3: 71-80
Lemos, E.M., Santoro, P.P., Tavares, R.A., Garcia, R.I.D., Furia, C.L.B. (2008) Oropharyngeal dysphagia in dermatomyosites: case report and literature review. Brazilian Journal of Otorhinolaryngology, 74(6): 938-940
Magnabosco, N.A.E., Westphalen, F.H. (2013) Analysis of oral complications related to cancer therapy. Archives of Oral Research, 9(658): 159
Melkoumov, A., Goupil, M., Louhichi, F., Raymond, M., de Repentigny, L., Leclair, G. (2013) Nystatin nanosizing enhances in vitro and in vivo antifungal activity against Candida albicans. Journal of antimicrobial chemotherapy, 68(9): 2099-105
Miranda-Rius, J., Brunet-Llobet, L., Lahor-Soler, E., Farré, M. (2015) Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. International journal of medical sciences, 12(10): 811-24
Mortazavi, S., Imanimoghaddam, M., Davachi, B., i dr. (2016) Evaluation of magnetic resonance sialography and ultrasonography findings in salivary glands of patients with xerostomia. Cumhuriyet Dent. J, 19: 23-34
Moslemi, D., Nokhandani, A.M., Otaghsaraei, M.T., Moghadamnia, Y., Kazemi, S., Moghadamnia, A.A. (2016) Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer: A review of the current literature. Radiotherapy and oncology, 120(1): 13-20
Naidu, M.U.R., Ramana, G.V., Rani, P.U., Mohan, lyyapu K., Suman, A., Roy, P. (2004) Chemotherapy-Induced and/or Radiation Therapy-Induced Oral Mucositis-Complicating the Treatment of Cancer. Neoplasia, 6(5): 423-431
Noll, S.F., Bender, C.E., Nelson, M.C. (1996) Rehabilitation of patients with swallowing disorders. Philadelphia: W.B. Saunders, 1st ed
Pai, S., Ghezzi, E.M., Ship, J.A. (2001) Development of a Visual Analogue Scale questionnaire for subjective assessment of salivary dysfunction. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 91(3): 311-316
Pinna, R., Campus, G., Cumbo, E., Mura, I., Milia, E. (2015) Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage. Therapeutics and Clinical Risk Management, str. 171
Raber-Durlacher, J.E., Brennan, M.T., Verdonck-de, L.I.M., Gibson, R.J., Eilers, J.G., Waltimo, T., Bots, C.P., Michelet, M., Sollecito, T.P., Rouleau, T.S., Sewnaik, A., Bensadoun, R., Fliedner, M. (2012) Swallowing dysfunction in cancer patients. Supportive Care in Cancer, 20(3): 433-443
Savioli, C., Ribeiro, A.C.M., Fabri, G.M.C., Calich, A.L., Carvalho, J., Silva, C.A., Viana, V.S.T., Bonfá, E., Siqueira, J.T.T. (2012) Persistent periodontal disease hampers anti-tumor necrosis factor treatment response in rheumatoid arthritis. Journal of clinical rheumatology, 18(4): 180-4
Scully, C., Sonis, S., Diz, P. (2006) Oral mucositis. Oral Diseases, 12(3): 229-241
Scully, C., Epstein, J., Sonis, S. (2003) Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy: part 1, pathogenesis and prophylaxis of mucositis. Head & neck, 25(12): 1057-70
Siqueira, J.T.T., Jales, S., Vilarim, R.C.B. (2013) Dor orofacial e cuidados paliativos orais em pacientes com câncer. Revista Onco., 25-8
Slade, G.D., Spencer, A.J. (1994) Development and evaluation of the Oral Health Impact Profile. Community Dent Health., 11(1): 3-11
Tan, E.C. K., Lexomboon, D., Sandborgh-Englund, G., Haasum, Y., Johnell, K. (2017) Medications That Cause Dry Mouth As an Adverse Effect in Older People: A Systematic Review and Metaanalysis. Journal of the American Geriatrics Society, 66(1): 76-84
Tunkel, A.R., Sepkowitz, K.A. (2002) Infections Caused by Viridans Streptococci in Patients with Neutropenia. Clinical Infectious Diseases, 34(11): 1524-1529
Turner, L., Mupparapu, M., Akintoye, S.O. (2013) Review of the complications associated with treatment of oropharyngeal cancer: a guide for the dental practitioner. Quintessence international, 44(3): 267-79
Wang, T., Chang, Y., Wu, M., Lin, L. (2004) Evaluating Swallowing Dysfunction Using a 100-ml Water Swallowing Test. Dysphagia, 19(1): 43-47
Wong, H.M. (2014) Oral Complications and Management Strategies for Patients Undergoing Cancer Therapy. Scientific World Journal, 2014: 1-14
World Health Organization (1979) Handbook for reporting results of cancer treatment. Geneve

O članku

jezik rada: engleski
vrsta rada: izvorni naučni članak
DOI: 10.2298/AOO1701009N
objavljen u SCIndeksu: 22.01.2018.
metod recenzije: jednostruko anoniman
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