članak: 7 od 9  
Back povratak na rezultate
Materia medica
2010, vol. 26, br. 2, str. 41-45
jezik rada: engleski
prikaz slučaja
Bilateralni metahroni tumori germinativnih ćelija testisa sa različitom histologijom i dugim slobodnim intervalom - prikaz dva slučaja
aUniverzitet u Beogradu, Medicinski fakultet, KBC 'Zemun'
bKlinički centar Srbije, Urološka klinika, Beograd + Poliklinika 'Argirović', Urologija, Beograd


Sažetak

Prikazana su dva slučaja metahronih tumora germinativnih ćelija testis (neseminomski/seminomski) posle hemioterapije na bazi cisplatine za prvi tumor germinativnih ćelija, koji su se prezentovali u kliničkom stadijumu (KS) I i II B, respektivno. Oba pacijenta su imala dug vremenski interval od 17 i 7 godina, sa različitim trajanjem od početka prvih simptoma do histopatološke dijagnoze (3 meseca I 20 dana) iziskujući orhiektomiju i organ prezervirajuću hirurgiju, respektivno. Uprkos prisustva KS - I seminoma, prvi pacijent je primio jedan ciklus adjuvantne hemioterapije sa karboplatinom (AUC-7) usled prisustva faktora rizika (tumor > 4 cm u dijametru, infiltracija rete testis), dok je drugi podvrgnut samo praćenju.

Ključne reči

Tumor testis; bilateralan; hemioterapija; praćenje; organ prezervirajuća hirurgija

Reference

Albers, P. (2006) Organ-sparing surgery for testicular lesions. Eur Urol, 5 (Suppl 5), str. 522-524
Aparicio, J., Germa, J.R., del Mundo, G.X., i dr. (2005) Second Spanish germ cell cancer cooperative group: Riskadapted management of patients with clinical stage I seminoma: The second Spanish germ cell cancer cooperative group study. J Clin Oncol, 23(34), str. 8717-8723
Argirovic, D., Radosevic-Jelic, L.M., Argirovic, A. (2009) The long-term side effects of adjuvant radiotherapy vs carboplatin chemotherapy in clinical stage A seminomatous testicular tumors. EUROPEAN UROLOGY SUPPLEMENTS, vol. 8, br. 8, str. 674-674
Argirović, D., Radosević, J.I. (1995) Bilateral testicular germ cell tumors in patients with clinical stage A: Two centers 21 years experience. Eur Urol, 4 (Suppl 3): 171
Argirović, D., Argirović, A. (2008) Caracteristics and loutcome of bilateral germ cell tumors. Eur Urol Meet, 3(8): 47
Argirović, D., Hadži-Đokić, J., Micić, S., Starčević-Božović, A. (1994) Cisplatin-based chemotherapy does not prevent the risk of second testicular tumor. Arch urol, 16, (46-47), str. 125-135
Argirović, D., Adanja, G., Hadži-Đokić, J. (1997) The management of patients with clinical stage A non-seminomatous testicular tumors and persistently elevated serum tumor markers. Br J Urol, 80 (Suppl 8): 296
Argirović, D., Jelić, R.Lj., Cvetković, L.P. (1998) Incidence of contralateral germ-cell testicular and second neoplasm: Report of two institutions experience. Br J Urol, 80 (Suppl 8): 376
Argirović, D., Jelić, R.L., Hadži-Đokić, J., i dr. (1998) Incidence of bilateral germ cell tumors. Eur Urol, 37 (Suppl 1): 431
Argirović, Đ.M. (1981) Urološko- onkološki aspekti dijagnoze i tretmana tumora testisa. Beograd: Medicinski Fakultet, Magistarski rad
Argirović, Đ.M. (1992) Mesto i uloga različitih metoda lečenja neseminomskih tumora testisa. Beograd: Medicinski fakultet, Doktorska disertacija
Fordham, M.V.P., Mason, M.D., Blackmore, C., Hendry, W.F., Horwich, A. (1990) Management of contralateral testis in patients with testicular germ cell cancer. British Journal of Urology, 65(3): 290-293
Gerl, A., Hentrich, M., Clemm, C., i dr. (1997) Characteristics and outcome of bilateral testicular germ cell tumors. Eur J Cancer, 33 (Suppl 8):41
Giwercmann, L.A., Skakkebeck, N.E., Brunn, E., Fidmot-Miller, C. (1987) Ultrasound in detection of early neoplasia of the testis. Int J Nadrol, 10 (1), str. 187-190
Huyghe, E., Matsuda, T., Thonneau, P. (2003) Increasing incidence of testicular cancer worldwide: A review. J Urol, 170(1): 5-11
Johnson, J.O., Mattrey, R.F., Phillipson, J. (1990) Differentiation of seminomatous from nonseminomatous testicular tumors by MRI. Am J Roentgenol, 154, 93, str. 539-543
Klein, E.A. (1993) Tumor markers in testis cancer. Urol Clin North Am, 20 (1), str. 67-73
Mattrey, R.F. (1991) Magnetic resonance of the scrotum. Semin Ultrasound CT MR, 12(2), str. 95-108
Osterlind, B.J.G., Abildgard, N., i dr. (1991) Risk of bilateral testicular germ cell cancer in Denmark: 1960-1980. J Natl Cancer Inst, 83, str. 1391-1395
Richie, J.P., Birnholz, J., Garnick, M.J. (1982) Ultrasonography as a diagnostic adjunctive for the evaluation of masses in the scrotum. Surg Gynecol Obstet, 154(5), str. 695-698
Thurner, J., Hricak, C.P.R., Pibel, R.S., Filly, R.A. (1988) Imaging the testis: Comparison between MR imaging and US. Radiology, 167(3), str. 631-636