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Scripta Medica
2015, vol. 46, iss. 1, pp. 43-48
article language: English
document type: Original Scientific Paper
doi:10.5937/ScriMed1501043D


Influence of age and gender on asymptomatic carotid disease
aUniversity of Banja Luka, Faculty of Medicine, Banja Luka, Republic of Srpska, BiH
bUniversity of Banja Luka, Faculty of Architecture and Civil Engineering, Banja Luka, Republic of Srpska, BiH

e-mail: neurologija@blic.net

Abstract

Introduction: Stroke is one of the most severe and the most common diseases of modern man. Prevention is necessary in order to detect people who have risk factors for it. Objective: To determine the frequency of asymptomatic carotid disease in people of different ages. Subjects and methods: The project encompassed the part of population, that is, groups at high risk for stroke from the Republic of Srpska. 20 240 patients were examined - there were 12797 (63.23%) females and 7443 (36.77%) males. The study protocol was created, as well as adequate software products to support all phases of project implementation such as preparation of marketing materials, doctors' appointments, building of application for doctors and nurses to record patients' data, reports, analysis and conclusion. Upon completion of the project, data were statistically processed and the analysis of obtained results was conducted. Discussion: Pathological changes in blood vessels were noticed through the ultrasound examination of the aforementioned blood vessels of the neck and head, and the degree of narrowing of the blood vessels was determined. Furthermore, adequate measures and treatment to prevent progression of the aforementioned as well as the occurrence of stroke were applied. On the basis of the obtained data, it was concluded that the age was one of the most significant predisposing factors for the development of asymptomatic carotid disease. It was also noted that females were, more than men, prone to developing carotid asymptomatic disease. Conclusion: Average stenosis of all respondents was 18.36% (in females, stenosis was approximately 3.92% lower and it was 16.92%, when compared to males - 20.84% ). Overall median was 16% (in females 15% and it was 5% lower than in men - 20%).

Keywords

ultrasound of the blood vessels of the neck and head; prevention; age; gender

References

Autret, A., Saudeau, D., Bertrand, PH., Pourcelot, L., Marchal, C., de Boisvilliers, S. (1987) Stroke risk in patients with carotid stenosis. Lancet, 329(8538): 888-890
Beks, P.H.J., Mackaay, A.J.C., de Vries, H., de Neeling, J.N.D., Bouter, L.M., Heine, R.J. (1997) Carotid artery stenosis is related to blood glucose level in an elderly Caucasian population: the Hoorn Study. Diabetologia, 40(3): 290-298
Bots, M.L., Breslau, P.J., Briët, E., de Bruyn, A.M., van Vliet, H.H., van den Ouweland, F.A., de Jong, P.T., Hofman, A., Grobbee, D.E. (1992) Cardiovascular determinants of carotid artery disease. The Rotterdam Elderly Study. Hypertension, 19(6_pt_2): 717-720
Chan, A., Beach, K.W., Martin, D.C., Strandness, D.E. (1983) Carotid Artery Disease in NIDDM Diabetes. Diabetes Care, 6(6): 562-569
Colgan, M.P., Strode, G.R., Sommer, J.D., Gibbs, J.L., Sumner, D.S. (1988) Prevalence of asymptomatic carotid disease: Results of duplex scanning in 348 unselected volunteers. Journal of Vascular Surgery, 8(6): 674-678
Fabris, F., Zanocchi, M., Bo, M., Fonte, G., Poli, L., Bergoglio, I., Ferrario, E., Pernigotti, L. (1994) Carotid plaque, aging, and risk factors. A study of 457 subjects. Stroke, 25(6): 1133-1140
Harer, C., Gusev, E.I. (2009) Asymptomatic cervical artery stenoses in Moscow. Acta Neurologica Scandinavica, 93(4): 286-290
Hennerici, M., Hülsbömer, H.-B., Hefter, H., Lammerts, D., Rautenberg, W. (1987) Natural history of asymptomatic extracranial arterial disease: results of a long-term prospective study. Brain, 110(3): 777-791
Inzitari, D., Eliasziw, M., Gates, P., Sharpe, B.L., Chan, R.K.T., Meldrum, H.E., Barnett, H.J.M. (2000) The Causes and Risk of Stroke in Patients with Asymptomatic Internal-Carotid-Artery Stenosis. New England Journal of Medicine, 342(23): 1693-1701
Josse, M.O., Touboul, P.J., Mas, J.L., Laplane, D., Bousser, M.G. (1987) Prevalence of Asymptomatic Internal Carotid Artery Stenosis. Neuroepidemiology, 6(3): 150-152
Langsfeld, M., Lusby, R.J. (1988) The spectrum of carotid artery disease in asymptomatic patients. J Cardiovasc Surg., 29: 687-691
Lindgren, A., Roijer, A., Norrving, B., Wallin, L., Eskilsson, J., Johansson, B.B. (1994) Carotid artery and heart disease in subtypes of cerebral infarction. Stroke, 25(12): 2356-2362
Norris, J.W., Zhu, C.Z., Bornstein, N.M., Chambers, B.R. (1991) Vascular risks of asymptomatic carotid stenosis. Stroke, 22(12): 1485-1490
o`Holleran Lawrence, W., Kennelly, M.M., McCiurken, M., Johnson, J.M. (1987) Natural history of asymptomatic carotid plaque. American Journal of Surgery, 154(6): 659-662
o`Leary D.H., Polak, J.F., Kronmal, R.A., Kittner, S.J., Bond, M.G., Wolfson, S.K., Bommer, W., Price, T.R., Gardin, J.M., Savage, P.J. (1992) Distribution and correlates of sonographically detected carotid artery disease in the Cardiovascular Health Study. The CHS Collaborative Research Group. Stroke, 23(12): 1752-60
o`Leary Daniel, H., Anderson, K.M., Wolf, P.A., Evans, J.C., Poehlman, H.W. (1992) Cholesterol and carotid atherosclerosis in older persons: The framingham study. Annals of Epidemiology, 2(1-2): 147-153
Pascazio, L., Sabbadini, G., Rieppi, S., Curri, G. (1994) Carotid and lower limbs arterial atheromasic disease in elderly patients with hypertensive left ventricular hypertrophy. Cardiovascular Imaging, 6: 45-49
Primatesta, P., Allender, S., Ciccarelli, P., Doring, A., Graff-Iversen, S., Holub, J., Panico, S., Trichopoulou, A., Verschuren, W.M. M. (2007) Cardiovascular surveys: manual of operations. European Journal of Cardiovascular Prevention & Rehabilitation, 14(3_suppl): S43-S61
Pujia, A., Rubba, P., Spencer, M.P. (1992) Prevalence of extracranial carotid artery disease detectable by echo-Doppler in an elderly population. Stroke, 23(6): 818-822
Sutton-Tyrrell, K., Alcorn, H.G., Wolfson, S.K., Kelsey, S.F., Kuller, L.H. (1993) Predictors of carotid stenosis in older adults with and without isolated systolic hypertension. Stroke, 24(3): 355-361
Thom, T., Haase, N., Rosamond, W., Howard, V.J., Rumsfeld, J., Manolio, T., Zheng, Z., Flegal, K., o`Donnell Christopher,, Kittner, S., Lloyd-Jones, D., Goff, D.C., Hong, Y., Adams, R., Friday, G. (2006) Heart disease and stroke statistics-2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation, 113: e85-e151
van Merode, T., Hick, P., Hoeks, P.G., Reneman, R.S. (1985) Serum HDL/total cholesterol ratio and blood pressure in asymptomatic atherosclerotic lesions of the cervical carotid arteries in men. Stroke, 16(1): 34-38