• citations in SCIndeks: 0
  • citations in CrossRef:[2]
  • citations in Google Scholar:[]
  • visits in previous 30 days:16
  • full-text downloads in 30 days:11


article: 5 from 7  
Back back to result list
2014, vol. 30, iss. 69, pp. 1342-1347
Application of soft laser in the treatment of Herpes labialis: Pilot study
aUniveristy of Niš, Faculty of Medicine, Clinic of Stomatology
bUniveristy of Niš, Faculty of Sport and Physical Education
Keywords: soft laser; therapy; Herpes labialis
Introduction: Soft laser could be used for the treatment of different painful diseases and conditions in the oral cavity. One of them is Herpes labialis. The aim of the paper was to study the efficiency of soft laser in the treatment of Herpes labialis. Material and method: The study included 43 patients. Laser therapy was applied in 23 patients, whereas 20 patients were treated by Ung. Acycklovir. Results: The level of statistical significance of differences in mean values of pain between the groups was maximum (p <0.001). Patients with herpetic lesions benefit from laser therapy in terms of shortening the progression of the disease, pain, tingling and burning. The patients treated with laser had significantly lower mean value of the pain compared to those treated with Ung. Acyklovir (p <0.05). Conclusion: Based on the obtained results, it can be concluded that the soft laser proved to be an effective therapy in the treatment of Herpes labialis, and, therefore, is recommended in its treatment.
Arduino, P.G., Porter, S.R. (2006) Oral and perioral herpes simplex virus type 1 (HSV-1) infection: review of its management. Oral diseases, 12(3): 254-70
Beeson, W.H., Rachel, J.D. (2002) Valacyclovir Prophylaxis for Herpes Simplex Virus Infection or Infection Recurrence Following Laser Skin Resurfacing. Dermatologic Surgery, 28(4): 331-336
Bello-Silva, M.S., de Freitas, P.M., Aranha, A.C.C., Lage-Marques, J.L., Simões, A., de Paula, E.C. (2010) Low- and high-intensity lasers in the treatment of herpes simplex virus 1 infection. Photomedicine and laser surgery, 28(1): 135-9
Cekić-Arambašin, A., Đurđević-Matić, A., Mravak-Stipetić, M., Bilić, A. (1990) The eficiency of low power laser in treatment of oral symptoms. Acta Stomatologica Croatica, a24, str. 281-288
Cernavin, I., Pugatschew, A., Boer, N., Tyas, M.J. (1994) Laser applications in dentistry: A review of the literature. Australian Dental Journal, 39(1): 28-32
Coluzzi, D.J., Convissar, R.A. (2007) Laser applications in fixed prosthodontics. in: Coluzzi D.J., Convissar R.A. [ed.] Atlas of laser applications in dentistry, Hanover Park: Quintessence Publishing, str. 91-116
de Carvalho, R.R., de Paula, E.F., Ramalho, K.M., Antunes, J.L.F., Bezinelli, L.M., de Magalhães, M.H.C.G., Pegoretti, T., de Freitas, P.M., de Paula, E.C. (2010) Effect of laser phototherapy on recurring herpes labialis prevention: an in vivo study. Lasers in medical science, 25(3): 397-402
de Paula, E.C., Bezinelli, L.M., de Paula, E.F., da Graça, L.R.M., Ramalho, K.M., Bello-Silva, M.S., Esteves-Oliveira, M. (2011) Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-year follow-up. Lasers in Medical Science, 27(5): 1077-1083
Donnarumma, G., De, G.V., Fusco, A., Farina, E., Baroni, A., Esposito, V., Contaldo, M., Petruzzi, M., Pannone, G., Serpico, R. (2010) Inhibition of HSV-1 replication by laser diode-irradiation: possible mechanism of action. International journal of immunopathology and pharmacology, 23(4): 1167-76
Dougal, G., Kelly, P. (2001) A pilot study of treatment of herpes labialis with 1072 nm narrow waveband light. Clinical and Experimental Dermatology, 26(2): 149-154
Gilioli, G., Taparelli, F., Fornaciari, A., Palmieri, B., Celani, M. (1985) Studio ultrastrutturale di colturecellulari vero infettate con virus Herpes Simplex e sottoposte all'- azione Laser. MLaser Rep, [Ultrastructural study of cell cultures infectwith herpes simplex virus and subjectto the action of laser], 3, 28-31; In Italian
Karu, T. (1989) Photobiology of low-power laser effects. Health Phys, 56(5): 691-704
Maiman, T.H. (1960) Stimulated Optical Radiation in Ruby. Nature, 187(4736): 493-494
Maričić, B., Mady, L., Hraste, J. (1997) Analgetički učinak lasera u stomatološkoj terapiji. Acta Stomatologica Croatica, 21: 291-301
Marotti, J., Sperandio, F.F., Fregnani, E.R., Aranha, A.C., de Freitas, P.M., de Eduardo, P. (2010) Highintensity laser and photodynamic therapy as a treatment for recurrent herpes labialis. PhotomLaser Surg, 28(3); 439-444; doi: / pho. 2522; 2009; 1089; 10
Moritz, A., Beer, F., Goharkhay, K., Schoop, U., i dr. (2006) Oral laser application. Quintessenz Verlags- GmbH
Navarro, R., Marquezan, M., Cerqueira, D.F., Silveira, B.L.D.A., Corrêa, M.S.N.P. (2007) Low-level-laser therapy as an alternative treatment for primary herpes simplex infection: a case report. Journal of clinical pediatric dentistry, 31(4): 225-8
Novoselova, E.G., Glushkova, O.V., Cherenkov, D.A., Chudnovsky, V.M., Fesenko, E.E. (2006) Effects of low-power laser radiation on mice immunity. Photodermatology, photoimmunology & photomedicine, 22(1): 33-8
Orlov, S., Kojović, D., Mirković, B., Kesić, L.J., Petrović, D., Pešić, Z. (2007) Oralnamedicina. Niš, 94-96
Sanchez, P.J.M., Femenías, J.L.C., Tejeda, A.D., Tunér, J. (2012) The Effect of 670-nm Low Laser Therapy on Herpes Simplex Type 1. Photomedicine and Laser Surgery, 30(1): 37-40
Schindl, A., Neumann, R. (1999) Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study. Journal of investigative dermatology, 113(2): 221-3
Sperandio, F.F., Marotti, J., Aranha, A.C., Eduardo, C.P. (2009) Photodynamic therapy for the treatment of recurrent herpes labialis: preliminary results. Gen Dent, 57(4); 415-419
Strang, R., Moseley, H., Carmichael, A. (1988) Soft lasers: Have they a place in dentistry?. Br Dent J, 165(6): 221-5
Tunér, J., Hode, L. (2007) The laser therapy handbook. Grangesberg: Prima Books
Vélez-González, M., Urrea-Arbeláez, A., Nicolas, M., Serra-Baldrich, E., Perez, J.L., Pavesi, M., Camarasa, J.M.G., Trelles, M.A. (1995) Treatment of relapse in herpes simplex on labial & facial areas and of primary herpes simplex on genital areas and area pudenda with low power laser (He- Ne) or Acyclovir administerorally. SPIE Proc, 2630: 43-50


article language: Serbian, English
document type: Case Report
DOI: 10.5937/asn1469342B
published in SCIndeks: 30/07/2015

Related records