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Vojnosanitetski pregled
2009, vol. 66, br. 2, str. 166-168
jezik rada: srpski
vrsta rada: prikaz slučaja
objavljeno: 27/04/2009
doi: 10.2298/VSP0902166J
Atrofija prednjeg režnja hipofize kao kasna komplikacija hemoragijske groznice sa renalnim sindromom
aVojnomedicinska akademija, Klinika za nefrologiju, Beograd
bVojnomedicinska akademija, Klinika za endokrinologiju, Beograd

Sažetak

Uvod. Hemoragijska groznica sa bubrežnim sindromom (HGBS) je akutno infektivno multisistemsko oboljenje koje se odlikuje pojavom febrilnosti, hemoragijama i akutnom bubrežnom insuficijencijom. Krvarenje u prednji režanj hipofize sa posledičnom nekrozom tkiva obično se javlja u akutnoj fazi teških kliničkih formi HGBS, dok se atrofija prednjeg režnja hipofize sa smanjenom funkcijom žlezde javlja nakon faze oporavka. Prikaz bolesnika. Prikazan je bolesnik sa razvojem hronične bubrežne insuificijencije i hipopituitarizmom kao komplikacijom koja je dijagnostikovana šest godina nakon akutne infekcije prouzrokovane hanta virusima. Magnetnom rezonancijom regiona hipofize ustanovljena je atrofija hipofize i prazna sella turcica. Zaključak. S obzirom na učestalost ove virusne infekcije i njen endemski karakter u pojedinim krajevima naše zemlje, neophodno je razmišljati i o parcijalnom i/ili kompletnom gubitku hipofizne funkcije kao kasnoj komplikaciji HGBS.

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