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2020, vol. 49, br. 1, str. 9-14
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Karakteristike sifilisa u populaciji Beograda u periodu od 2009. do 2018. godine
Syphilis characteristics in Belgrade population, in period from 2009 to 2018
aCity Institute for Skin and Venereal Disease, Belgrade bUniverzitet u Beogradu, Medicinski fakultet, Institut za epidemiologiju cCity Institute for Public Health, Belgrade
e-adresa: kristiv@eunet.rs
Projekat: Epidemiološka istraživanja (MPNTR - 175042)
Ključne reči: stope dijagnostikovanog sifilisa; rani sifilis; kasni sifilis; Beograd
Keywords: confirmed syphilis rate; early syphilis; late syphilis; Belgrade
Sažetak
Uvod/Cilj: Početkom novog milenijuma došlo je do značajnog porasta obolevanja od sifilisa u populaciji Srbije. Cilj ovog rada je bio da se utvrdi učestalost obolevanja od sifilisa u populaciji Beograda u periodu od 2009. do 2018. godine, kao i udeo ranog i kasnog sifilisa u ukupnom broju obolelih. Metode: U radu su korišćeni podaci o novoregistrovanim slučajevima obolevanja od sifilisa, dijagnostikovanog u bilo kom stadijumu bolesti, uzetih iz obaveznih prijava za zarazne bolesti koje stižu sa čitave teritorije Beograda u Gradski zavod za zaštitu zdravlja. Rezultati: U periodu od 2009. do 2018. godine sifilis je dijagnostikovan po prvi put kod 631 osobe, 46 žena (7,3%) i 585 muškaraca (92,7%) - odnos muškarci/žene bio je 12,7 :1. Uz godišnje oscilacije, broj dijagnostikovanih bolesnika je kod muškaraca rastao i najveća nestandardizovana stopa je zabeležena u 2018. godini (17,7 na 100.000). Stopa dijagnostikovanog sifilisa kod žena je varirala po godinama od 0,2 na 100.000, u 2018. godini, do 0,9 na 100.000, u 2012. godini. Uz to, kod žena je značajno češće nego kod muškaraca sifilis po prvi put dijagnostikovan u kasnoj fazi (45,7% prema 12,8%; r < 0,001). Zaključak: Podaci o učestalosti dijagnostikovanog sifilisa u populaciji Beograda su u skladu sa podacima iz drugih evropskih zemalja. Međutim, činjenica da je sifilis kod nekih obolelih otkriven u kasnom stadijumu ukazuje na to da stope dijagnostikovanog sifilisa, posebno kod žena, u našoj sredini ne predstavljaju pravi pokazatelj epidemiološke situacije.
Abstract
Introduction/Objective: At the beginning of the new millennium, a frequency of syphilis significantly increased in the population of Serbia. The aim of the present study was to determine the frequency of syphilis in Belgrade population from 2009 to 2018, as well as the proportion of early and late syphilis in the total number of patients. Methods: The paper used data on newly reported cases of syphilis diagnosed at any stage of the disease, taken from compulsory infectious disease applications coming from the entire territory of Belgrade to the City Institute for Health Protection. Results: Between 2009 to 2018, syphilis was diagnosed for the first time in 631 persons, 46 females (7.3%) and 585 males (92.7%), the male / female ratio was 12.7:1. With some annual fluctuations, the number of newly diagnosed (confirmed) syphilis increased in males and the highest crude rate was recorded in 2018 (17.7 per 100 000). The rates of diagnosed syphilis in women varied by age, from 0.2 per 100 000 in 2018, to 0.9 per 100 000 in 2012. In addition, women were significantly more frequently diagnosed with late-stage syphilis than men (45.7% vs. 12.8%; p< 0.001). Conclusion: Data on the incidence of diagnosed syphilis in the Belgrade population are consistent with data from other European countries. However, the fact that in some patients syphilis was detected at late stage suggests that rates of diagnosed syphilis, especially in women, in our population did not represent the real epidemiological situation.
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Reference
|
|
 
|
*** (2018) Congenital syphilis in the USA. Lancet, 392(10154): 1168-1168
|
|
|
Abu-Rajab, K., Wallace, L.A. (2011) Heterosexual transmission of infectious syphilis in central Scotland, 2009. International Journal of STD & AIDS, 22(9): 517-518
|
|
|
Acheson, P., Mcgivern, M., Frank, P., Kunonga, E., Simms, I., Tayal, S., Thody, E., Waldram, A., Kibirige, J. (2011) An ongoing outbreak of heterosexually-acquired syphilis across Teesside, UK. International Journal of STD & AIDS, 22(9): 514-516
|
|
|
Anderson, H., Williams, A., Zirngibl, M., Fatima, J., Symonds, M., Goh, B. (2011) A decade of early syphilis in East and inner city London. Sexually Transmitted Infections, 87(Suppl 1): A119-A119
|
|
|
Begović-Vuksanović, B., Begović-Lazarević, I., Uzelac-Škorić, A., Marić, S. (2014) HIV/AIDS in Belgrade between 2003. and 2012. Zdravstvena zaštita, vol. 43, br. 6, str. 1-6
|
|
|
Bjekić, M., Šipetić-Grujičić, S., Vlajinac, H., Nikolić, A. (2018) Oral sex related knowledge and oral sex behavior among homosexual and heterosexual men in Belgrade: A cross-sectional study. Indian J Dermatol Venereol Leprol, 84(5): 563-568
|
|
|
Bjekić, M., Vlajinac, H., Šipetić, S., Kocev, N. (2001) Trends of gonorrhoea and early syphilis in Belgrade: 1985-1999. Sexually Transmitted Infections, 77(5): 387-388
|
|
|
Bjekić, M., Vlajinac, H., Šipetić-Grujičić, S. (2016) Characteristics of gonorrhea and syphilis cases among the Roma ethnic group in Belgrade, Serbia. Brazilian Journal of Infectious Diseases, 20(4): 349-353
|
|
2
|
Bjekić, M., Šipetić-Grujičić, S., Begović-Vuksanović, B., Rafailović, N., Vlajinac, H. (2017) Syphilis resurgence in Belgrade, Serbia, in the new millennium: An outbreak in 2014. Central European Journal of Public Health, 25(4): 277-281
|
|
|
Bjekić, M., Vlajinac, H., Dunić, I. (2019) Razlike u seksualnom ponašanju između obolelih od sifilisa i gonoreje u Beogradu. Zdravstvena zaštita, vol. 48, br. 4, str. 15-24
|
|
|
Burgos, A., Romero, D.P., Gálvez, R., Ramos, R., García, S.S., Martínez, A.L., et al. (2015) Analysis of serological tests in almeriense pregnant women in the last year. J Perinat Med, 43: P-0363
|
|
|
European Centre for Disease Prevention and Control (ECDC) (2019) Syphilis and congenital syphilis in Europe: A review of epidemiological trends (2007-2018) and options for response. Stockholm
|
|
|
European Centre for Disease Prevention and Control (2019) Syphilis. u: ECDC: Annual epidemiological report for 2017, Stockholm
|
|
|
Garnett, G.P., Aral, S.O., Hoyle, D.V., Cates, W., Anderson, R.M. (1997) The natural history of syphilis: Implications for the transmission dynamics and control of infection. Sex Transm Dis, 24(4): 185-200
|
|
|
Institut za javno zdravlje Srbije 'Dr Milan Jovanović Batut' (2018) Izveštaj o zaraznim bolestima u Republici Srbiji za 2017. godinu. Beograd
|
|
|
Lutomski, J.E., Shiely, F., Molloy, E.J. (2014) The prevalence of syphilis at childbirth in Ireland: A six-year review. Journal of Maternal-Fetal & Neonatal Medicine, 27(17): 1823-1825
|
|
2
|
Lynn, W.A., Lightman, S. (2004) Syphilis and HIV: A dangerous combination. Lancet Infectious Diseases, 4(7): 456-466
|
|
1
|
Newman, L., Rowley, J., Vander, H.S., Wijesooriya, N.S., Unemo, M., Low, N., Stevens, G., Gottlieb, S., Kiarie, J., Temmerman, M. (2015) Global estimates of the prevalence and incidence of four curable sexually transmitted infections in 2012 based on systematic review and global reporting. PLoS One, 10(12): e0143304-e0143304
|
|
|
Pala, S., Conti, C., Goldoni, P., Silvaggio, D., Nicolai, M., Schiariti, E., et al. (2018) A five year retrospective study on syphilis in the Sexual Transmitted Disease Centre (STDC) of the teaching Hospital Umberto I in Rome. Ann Ig, 20(1):66-70
|
|
|
Pearson, V., Matthias, J. (2018) Identification of Florida counties experiencing an outbreak of syphilis in females in 2016. Sex Transm Dis, 45:S70-S1
|
|
|
Serwin, A.B., Unemo, M. (2016) Syphilis in females in Bialystok, Poland: 2000-2015. Przegl Epidemiol, 70(2):273-80
|
|
|
Simms, I., Wallace, L., Thomas, D.R., Emmett, L., Shankar, A.G., Vinson, M., et al. (2014) Recent outbreaks of infectious syphilis, United Kingdom, January 2012 to April 2014. Eurosurveill, 19 (24):20833
|
|
|
van Aar, F., Den, D.C., van der Sande, M.A.B., Soetens, L.C., de Vries, H.J.C., van Benthem, B.H.B. (2017) Outbreaks of syphilis among men who have sex with men attending STI clinics between 2007 and 2015 in the Netherlands: A space-time clustering study. Sexually Transmitted Infections, 93(6): 390-395
|
|
|
Wijesooriya, N. S., Rochat, R.W., Kamb, M.L., Turlapati, P., Temmerman, M., Broutet, N., Newman, L.M. (2016) Global burden of maternal and congenital syphilis in 2008 and 2012: A Health systems modelling study. Lancet Global Health, 4(8): e525-e533
|
|
|
|
|