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Vojnosanitetski pregled
2016, vol. 73, iss. 8, pp. 774-778
article language: English
document type: Case Report
published on: 05/08/2016
doi: 10.2298/VSP141222053D
Creative Commons License 4.0
Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention
aMilitary Medical Academy, Clinic of Cardiology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade
bUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency Internal Medicine, Belgrade
cMilitary Medical Academy, Clinic of Cardiology, Belgrade
dMilitary Medical Academy, Clinic for Emergency Internal Medicine, Belgrade



Introduction. Stent thrombosis (ST) in clinical practice can be classified according to time of onset as early (0-30 days after stent implantation), which is further divided into acute (< 24 hours) and subacute (1-30 days), late (> 30 days) and very late (> 12 months). Myocardial reinfaction due to very late ST in a patient receiving antithrombotic therapy is very rare, and potentially fatal. The procedure alone and related mechanical factors seem to be associated with acute/subacute ST. On the other hand, in-stent neoatherosclerosis, inflammation, premature cessation of antiplatelet therapy, as well as stent fracture, stent malapposition, uncovered stent struts may play role in late/very late ST. Some findings implicate that the etiology of very late ST of baremetal stent (BMS) is quite different from those following drug-eluting stent (DES) implantation. Case report. We presented a 56-year old male with acute inferoposterior ST segment elevation myocardial infarction (STEMI) related to very late stent thrombosis, 9 years after BMS implantation, despite antithrombotic therapy. Thrombus aspiration was successfully performed followed by percutaneous coronary intervention (PCI) with implantation of DES into the previously implanted two stents to solve the instent restenosis. Conclusion. Very late stent thrombosis, although fortunately very rare, not completely understood, might cause myocardial reinfaction, but could be successfully treated with thrombus aspiration followed by primary PCI. Very late ST in the presented patient might be connected with neointimal plaque rupture, followed by thrombotic events.



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