Metrika članka

  • citati u SCindeksu: [1]
  • citati u CrossRef-u:0
  • citati u Google Scholaru:[=>]
  • posete u poslednjih 30 dana:3
  • preuzimanja u poslednjih 30 dana:1
članak: 8 od 30  
Back povratak na rezultate
Vojnosanitetski pregled
2013, vol. 70, br. 1, str. 51-56
jezik rada: engleski
vrsta rada: originalan članak
doi:10.2298/VSP111229024G


Morfometrijske karakteristike optičkog diska kod bolesnika sa miopijom i primarnim glaukomom otvorenog ugla
aUniverzitet u Beogradu, Medicinski fakultet
bFaculty of Medicine, Belgrade + Eye Clinic, University Medical Center Zvezdara, Belgrade
cFaculty of Medicine, Belgrade + Institute of Ophthalmology, Clinical Center of Serbia, Belgrade

e-adresa: ranko2010@gmail.com

Sažetak

Uvod/Cilj. Primarni glaukom otvorenog ugla je multifaktorijalna i progresivna neuropatija koja se karakteriše stečenim gubitkom ganglijskih ćelija retine i njihovih aksona. Jedan od faktora rizika od primarnog glaukoma otvorenog ugla je miopija preko 5 D. Cilj našeg rada bio je da procenimo da li veličina refrakcione greške utiče na morfometrijske karakteristike optičkog diska koristeći konfokalnu skening laser oftalmoskopiju u ispitivanju dve grupe pacijenata sa dijagnostikovanim primarnim glaukomom otvorenog ugla koji istovremeno imaju miopiju. Metode. Stotinu očiju od stotinu bolesnika koji imaju dijagnostikovan primarni glaukom otvorenog ugla i istovremeno miopiju bili su uključeni u našu studiju. Bolesnici su bili podeljeni u dve grupe: prva, sa miopijom < 5 D, a druga sa miopijom ≥ 5 D. Heidelberg retina tomografom analizirani su morfometrijski parametri optičkih diskova bolesnika u cilju utvrđivanja postojanja međusobne povezanosti između parametara u svakoj grupi posebno, kao i postojanja statistički značajne razlike među istoimenim parametrima obe grupe. Rezultati. Između dve grupe ispitanika utvrđeno je postojanje statistički značajnih razlika u sledećim parametrima: prečniku diska, površine ekskavacije, površini neuroretinlnog oboda i srednje RNFL debljine. Oštećenje neuroretinalnog oboda u grupi bolesnika sa visokom miopijom bilo je 27%, dok je u grupi bolesnika sa niskom miopijom bilo 14%. Najčešće oštećen segment neuroretinalnog oboda bolesnika sa visokom miopijom bio je nazalni, a kod bolesnika sa niskon miopijom donji temporalni. Najređe oštećen segment neuroretinalnog oboda u obe grupe bio je temporalni. Zaključak. Optički diskovi glaukomnih bolesnika sa visokom miopijom imaju veći prečnik, veću i iregularnije raspoređenu zonu oštećenja neuroretinalnog oboda, kao i tanji retinalni sloj nervnih vlakana od glaukomnih bolesnika sa niskom miopijom.

Ključne reči

Reference

Adegbehingbe, B.O., Ouertani, A.M. (2009) Confocal scanning laser tomography of the optic nerve head of glaucoma patients: Inter-correlation of disc parameters. Ghana medical journal, 43(4): 150-6
Airaksinen, P.J., Drance, S.M., Schulzer, M. (1985) Neuroretinal rim area in early glaucoma. American journal of ophthalmology, 99(1): 1-4
American Academy of Ophthalmology (2000) Glaucoma panel: Primary open-angle glaucoma: Preferred practice pattern. San Francisco: American Academy of Ophthalmology, p. 1-36
Budenz, D.L., Anderson, D.R., Varma, R., Schuman, J., Cantor, L., Savell, J., Greenfield, D.S., Patella, V.M., Quigley, H.A., Tielsch, J. (2007) Determinants of normal retinal nerve fiber layer thickness measured by Stratus OCT. Ophthalmology, 114(6): 1046-52
Choi, S., Lee, S. (2006) Thickness changes in the fovea and peripapillary retinal nerve fiber layer depend on the degree of myopia. Korean journal of ophthalmology, 20(4): 215-9
Cioffi, G.A., Robin, A.L., Eastman, R.D., Perell, H.F., Sarfarazi, F.A., Kelman, S.E. (1993) Confocal laser scanning ophthalmoscope. Reproducibility of optic nerve head topographic measurements with the confocal laser scanning ophthalmoscope. Ophthalmology, 100(1): 57-62
Citirik, M., Dilsiz, N., Batman, C., Zilelioglu, O. (2009) Comparative toxicity of 4 commonly used intravitreal corticosteroids on rat retina. Canadian Journal of Ophthalmology, 44(3): e3-e8
Dichtl, A., Jonas, J.B., Mardin, C.Y. (1996) Comparison between tomographic scanning evaluation and photographic measurement of the neuroretinal rim. American journal of ophthalmology, 121(5): 494-501
Durukan, H.A., Yucel, I., Akar, Y., Bayraktar, Z.M. (2004) Assessment of optic nerve head topographic parameters with a confocal scanning laser ophthalmoscope. Clinical & experimental ophthalmology, 32(3): 259-64
Eid, T.E., Spaeth, G.L., Moster, M.R., Augsburger, J.J. (1997) Quantitative differences between the optic nerve head and peripapillary retina in low-tension and high-tension primary open-angle glaucoma. American journal of ophthalmology, 124(6): 805-13
Fong, D.S., Epstein, D.L., Allingham, R.R. (1990) Glaucoma and myopia: Are they related?. International ophthalmology clinics, 30(3): 215-8
Golubović, S. (2010) Ophthalmology. Belgrade: Medical Faculty, Serbian
Hoffmann, E.M., Medeiros, F.A., Sample, P.A., Boden, C., Bowd, C., Bourne, R.R., Zangwill, L.M., Weinreb, R.N. (2006) Relationship between patterns of visual field loss and retinal nerve fiber layer thickness measurements. American journal of ophthalmology, 141(3): 463-471
Hoh, S., Lim, M.C.C., Seah, S.K.L., Lim, A.T.H., Chew, S., Foster, P.J., Aung, T. (2006) Peripapillary retinal nerve fiber layer thickness variations with myopia. Ophthalmology, 113(5): 773-7
Hougaard, J.L., Ostenfeld, C., Heijl, A., Bengtsson, B. (2006) Modelling the normal retinal nerve fibre layer thickness as measured by Stratus optical coherence tomography. Graefe's archive for clinical and experimental ophthalmology, 244(12): 1607-14
Jonas, J.B., Fernández, M.C., Stürmer, J. (1993) Pattern of glaucomatous neuroretinal rim loss. Ophthalmology, 100(1): 63-8
Jonas, J.B., Gusek, G.C., Naumann, G.O. (1988) Optic disk morphometry in high myopia. Graefe's archive for clinical and experimental ophthalmology, 226(6): 587-90
Leung, C.K.S., Chan, W., Yung, W., Ng, A.C.K., Woo, J., Tsang, M., Tse, R.K.K. (2005) Comparison of macular and peripapillary measurements for the detection of glaucoma: An optical coherence tomography study. Ophthalmology, 112(3): 391-400
Leung, C.K., Mohamed, S., Leung, K.S., Cheung, C.Y., Chan, S.L., Cheng, D.K., Lee, A.K., Leung, G.Y., Rao, S.K., Lam, D.S.C. (2006) Retinal nerve fiber layer measurements in myopia: An optical coherence tomography study. Investigative ophthalmology & visual science, 47(12): 5171-6
Medeiros, F.A., Zangwill, L.M., Bowd, C., Weinreb, R.N. (2004) Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma. Arch Ophthalmol, 122(6): 827-37
Mitchell, P., Hourihan, F., Sandbach, J., Wang, J.J. (1999) The relationship between glaucoma and myopia: The Blue Mountains Eye Study. Ophthalmology, 106(10): 2010-5
Perkins, E.S., Phelps, C.D. (1982) Open angle glaucoma, ocular hypertension, low-tension glaucoma, and refraction. Archives of ophthalmology, 100(9): 1464-7
Quigley, H.A. (1999) Neuronal death in glaucoma. Progress in retinal and eye research, 18(1): 39-57
Quigley, H.A., Katz, J., Derick, R.J., Gilbert, D., Sommer, A. (1992) An evaluation of optic disc and nerve fiber layer examinations in monitoring progression of early glaucoma damage. Ophthalmology, 99(1): 19-28
Quigley, H.A., Dunkelberger, G.R., Green, W.R. (1988) Chronic human glaucoma causing selectively greater loss of large optic nerve fibers. Ophthalmology, 95(3): 357-63
Quigley, H.A., Dunkelberger, G.R., Green, W.R. (1989) Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. American journal of ophthalmology, 107(5): 453-64
Seddon, J.M., Schwartz, B., Flowerdew, G. (1983) Case-control study of ocular hypertension. Archives of ophthalmology, 101(6): 891-4
Sommer, A., Katz, J., Quigley, H.A., Miller, N.R., Robin, A.L., Richter, R.C., Witt, K.A. (1991) Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss. Archives of ophthalmology, 109(1): 77-83
Tay, E., Seah, S.K., Chan, S., Lim, A.T.H., Chew, S., Foster, P.J., Aung, T. (2005) Optic disk ovality as an index of tilt and its relationship to myopia and perimetry. American journal of ophthalmology, 139(2): 247-52
Tuulonen, A., Airaksinen, P.J. (1991) Initial glaucomatous optic disk and retinal nerve fiber layer abnormalities and their progression. American journal of ophthalmology, 111(4): 485-90
Uchida, H., Yamamoto, T., Araie, M., Tomita, G., Shirakashi, M., Yoshikawa, K. (2005) Topographic characteristics of the optic nerve head measured with scanning laser tomography in normal Japanese subjects. Japanese journal of ophthalmology, 49(6): 469-76
Vernon, S.A., Rotchford, A.P., Negi, A., Ryatt, S., Tattersal, C. (2008) Peripapillary retinal nerve fibre layer thickness in highly myopic Caucasians as measured by Stratus optical coherence tomography. British journal of ophthalmology, 92(8): 1076-80
Vernon, S.A., Hawker, M.J., Ainsworth, G., Hillman, J.G., Macnab, H.K., Dua, H.S. (2005) Laser scanning tomography of the optic nerve head in a normal elderly population: The Bridlington eye assessment project. Investigative ophthalmology & visual science, 46(8): 2823-8
Wollstein, G., Garway-Heath, D.F., Hitchings, R.A. (1998) Identification of early glaucoma cases with the scanning laser ophthalmoscope. Ophthalmology, 105(8): 1557-63