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2011, vol. 50, iss. 3, pp. 81-89
Diagnosis and treatment of depression in persons with intellectual disability
aVocational College for Preschool Teachers, Kruševac
bClinical Center Kragujevac, Clinic of Psychiatry
cClinical Centre Kragujevac, Clinic for Neurology
dUniversity of Kragujevac, Faculty of Medical Sciences
Keywords: intellectual disability; depression; diagnosis of depression; treatment of depression
This paper considers, from the theoretical point of view, the problem of diagnosing and treatment of depressive disorders in people with intellectual disability (ID), relying primarily on the results of previous researches, which stress the etiological, symptomatic, diagnostic and therapeutic specifics when it comes to depression and its correlates in this population. The interest in mental health and psychopathology of people with ID intensified during the seventh decade of the previous century, when it became clear that some cognitive and behavioral symptoms are not, as hitherto thought, only a part or a consequence of the syndrome of intellectual disability, but a sign of ongoing mental disorder. So, the idea of ''dual diagnosis'' was born, and now it provides guidelines for the growing number of studies which theoretically and empirically review different issues of mental health problems in people with ID. Likewise, the observation of syndrome groups of genetic disorders resulting in intellectual disability has led to the narrowing of the circle of genetic syndromes that carry increased risk for the onset of depression and its correlates, such as: Down syndrome, Fragile X syndrome and Prader-Willi syndrome. Potential diagnostic problem in people with ID, when it comes to depression, may arise from 'diagnostic overshadowing' of depression symptoms, which often remain hidden under abnormal behavior and adjustment disorders, especially in patients with severe forms of ID. As a possible way to overcome these problems some authors have proposed the concept of 'behavioral equivalents of depression' or behavioral disorders that evidently can be associated with depression, such as social withdrawal, aggression, hostility, irritability, psychomotor agitation or retardation. Intensification of these forms of behavior may be a sign of developing depression, and in that sense, this view represents a useful starting point. When it comes to therapeutic approaches, there is a general tendency in favour of psycho pharmacotherapy in the treatment of depression, although there is a growing number of researches that prove the favourable effects of cognitivebehavioral and psychoanalytic psychotherapy.
Aman, M.G., Arnold, E.L., Armstrong, S.C. (1999) Review of serotonergic agents and perseverative behavior in patients with developmental disabilities. Mental Retardation and Developmental Disabilities Research Reviews, 5(4): 279-289
Antochi, R., Stavrakaki, C., Emery, P.C. (2003) Psychopharmaco logical treatments in persons with dual diagnosis of psychiatric disorders and developmental disabilities. Postgrad Med J, 9, str. 139-46
Antonacci, D.J., Attiah, N. (2008) Diagnosis and treatment of mood disorders in adults with developmental disabilities. Psychiatric quarterly, 79(3): 171-92
Argus, G.R., Terry, P.C., Bramston, P., Dinsdale, S.L. (2004) Measurement of mood in adolescents with intellectual disability. Research in developmental disabilities, 25(6): 493-507
Battaglia, A. (2011) Sensory impairment in mental retardation: a potential role for NGF. Archives italiennes de biologie, 149(2): 193-203
Bojanin, S.S., Kolar, D., Kolar, M. (2002) Mentalna retardacija i psihotični poremećaji. Psihijatrija danas, vol. 34, br. 3-4, str. 327-343
Carlino, D., de Vanna, M. (2011) Potential benefits and limitations of new technologies in the personalized treatment of depression. Rivista di psichiatria, 46(3): 155-71
Dosen, A. (2007) Integrative treatment in persons with intellectual disability and mental health problems. Journal of intellectual disability research, 51(Pt 1): 66-74
Dykens, E.M. (2007) Psychiatric and behavioral disorders in persons with Down syndrome. Mental Retardation and Developmental Disabilities Research Reviews, 13(3): 272-278
Emerson, E. (2003) Prevalence of psychiatric disorders in children and adolescents with and without intellectual disability. Journal of intellectual disability research, 47(Pt 1): 51-8
Esbensen, A.J., Benson, B.A. (2007) An evaluation of Beck's cognitive theory of depression in adults with intellectual disability. Journal of Intellectual Disability Research, 51: 14-24
Esbensen, A.J., Benson, B.A. (2006) A prospective analysis of life events, problem behaviours and depression in adults with intellectual disability. Journal of Intellectual Disability Research, 50(4): 248
Fletcher, R.J., Havercamp, S.M., Ruedrich, S.L., Benson, B.A., Barnhill, L.J., Cooper, S.A., i dr. (2009) Clinical usefulness of the diagnostic manual-intellectual disability for mental disorders in persons with intellectual disability: Results from a brief field survey. J Clin Psychiatry, 70, str. 1-8
Gray, K.M., Piccinin, A.M., Hofer, S.M., Mackinnon, A., Bontempo, D.E., Einfeld, S.L., Parmenter, T., Tonge, B.J. (2011) The longitudinal relationship between behavior and emotional disturbance in young people with intellectual disability and maternal mental health. Research in developmental disabilities, 32(3): 1194-204
Hemmings, C.P., Gravestock, S., Pickard, M., Bouras, N. (2006) Psychiatric symptoms and problem behaviours in people with intellectual disabilities. Journal of Intellectual Disability Research, 50(4): 269-276
Hranilovic, D., Bujas-Petkovic, Z., Vragovic, R., Vuk, T., Hock, K., Jernej, B. (2007) Hyperserotonemia in adults with autistic disorder. Journal of autism and developmental disorders, 37(10): 1934-40
Jahoda, A., Dagnan, D., Jarvie, P., Kerr, W. (2006) Depression, Social Context and Cognitive Behavioural Therapy for People who have Intellectual Disabilities. Journal of Applied Research in Intellectual Disabilities, 19(1): 81-89
Lambert, K.G. (2006) Rising rates of depression in today's society: Consideration of the roles of effort-based rewards and enhanced resilience in day-to-day functioning. Neuroscience & Biobehavioral Reviews, 30(4): 497-510
Langlois, L., Martin, L. (2008) Relationship between diagnostic criteria, depressive equivalents and diagnosis of depression among older adults with intellectual disability. Journal of Intellectual Disability Research, 52 (11): 896-904
Matson, J.L., Dempsey, T., Rivet, T.T. (2009) The Interrelationships of Psychopathology Symptoms on Social Skills in Adults with Autism or PDD-NOS and Intellectual Disability. Journal of Developmental and Physical Disabilities, 21(1): 39-55
Mcbrien, J.A. (2003) Assesment and diagnosis of depression in people with Intellectual Disability. Journal of Intellectual Disability, Part I, 1-13
McCabe, M.P., McGillyvray, J.A., Newton, D.C. (2006) Effectiveness of treatment programmes for depression among adults with mild/moderate intellectual disability. Journal of Intellectual Disability Research, 50(4): 239
McGillivray, J.A., McCabe, M. (2007) Early detection of depression and associated risk factors in adults with mild/moderate intellectual disability. Research in Developmental Disabilities, 28(1): 59
Mcgillivray, J.A., McCabe, M.P. (2009) Detecting and treating depression in people with mild intellectual disability: The views of key stakeholders. Br J Learn Disabil, 1-9
McGillivray, J.A., McCabe, M.P., Kershaw, M.M. (2008) Depression in people with intellectual disability: an evaluation of a staff-administered treatment program. Research in developmental disabilities, 29(6): 524-36
Mezulis, A.H., Hyde, J.S., Abramson, L.Y. (2006) The developmental origins of cognitive vulnerability to depression: temperament, parenting, and negative life events in childhood as contributors to negative cognitive style. Developmental psychology, 42(6): 1012-25
Mohr, C., Tonge, B.J., Einfeld, S.L. (2005) The development of a new measure for the assessment of psychopathology in adults with intellectual disability. J Intellect Disabil Res, 49(Pt 7): 469-80
Nevels, R.M., Dehon, E.E., Alexander, K., Gontkovsky, S.T. (2010) Psychopharmacology of aggression in children and adolescents with primary neuropsychiatric disorders: a review of current and potentially promising treatment options. Experimental and clinical psychopharmacology, 18(2): 184-201
Oberthür, A., Heller, R., Vogel, M., Körber, F., Rahimi, G., Hoopmann, M., Emmel, M., Roth, B., Vierzig, A. (2009) Smith-Lemli-Opitz syndrome--case report, diagnostics and therapeutic options. Zeitschrift für Geburtshilfe und Neonatologie, 213(5): 210-4
Potvin, O., Hudon, C., Dion, M., Grenier, S., Préville, M. (2011) Anxiety disorders, depressive episodes and cognitive impairment no dementia in community-dwelling older men and women. International journal of geriatric psychiatry, 26(10): 1080-8
Reeves, W.C., Strine, T.W., Pratt, L.A., Thompson, W., Ahluwalia, I., Dhingra, S.S., i dr. (2011) Public Health Surveillance Program Office: Mental illness surveillance among adults in the United States. MMWR Surveill Summ, 60(Suppl 3), str. 1-32
Taurines, R., Gerlach, M., Warnke, A., Thome, J., Wewetzer, C. (2011) Pharmacotherapy in depressed children and adolescents. World journal of biological psychiatry, 12 Suppl 1: 11-5
Tomić, K., Mihajlović, G. (2008) Mentalna retardacija i depresija. Engrami - časopis za kliničku psihijatriju, psihologiju i granične discipline, vol. 30, br. 1, str. 41-52
Tsakanikos, E., Bouras, N., Sturmey, P., Holt, G. (2006) Psychiatric co-morbidity and gender differences in intellectual disability. Journal of Intellectual Disability Research, 50(8): 582
Tsiouris, J.A. (2001) Diagnosis of depression in people with severe/profound intellectual disability. J Intellect Disabil Res, 45(Pt 2): 115-20
Venta, A., Sharp, C., Hart, J. (2011) The relation between anxiety disorder and experimental avoidance in inpatient adolescents. Psychol Assess, [Epub ahead of print]
Willner, P. (2005) The effectiveness of psychotherapeutic interventions for people with learning disabilities: a critical overview. Journal of intellectual disability research, 49(Pt 1): 73-85
Wittchen, H.U., Jacobi, F., Rehm, J., Gustavsson, A., Svensson, M., Jönsson, B., i dr. (2011) The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol, 21,(9),655-79


article language: English
document type: Review Paper
published in SCIndeks: 27/01/2012