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Medicinski pregled
2011, vol. 64, br. 7-8, str. 397-402
jezik rada: engleski
vrsta rada: stručni članak
objavljeno: 27/09/2011
doi: 10.2298/MPNS1108397J
Rezistencija Escherichiae coli iz fecesa zdravih osoba i iz hrane - indikator nivoa rezistencije na antibiotike u populaciji
Institute of Public Health of Vojvodina, Center for Microbiology, Novi Sad

e-adresa: mikrobiologija@izjzv.org.rs

Sažetak

Uvod. Escherichia coli kao deo normalne crevne flore može biti rezervoar gena rezistencije na antibiotike, a hrana je najznačajniji vektor za širenje rezistencije između ljudi i životinja. Cilj ovog rada bio je da se ispita osetljivost na najčešće korišćene antimikrobne lekove izolata Escherichiae coli iz stolica zdravih osoba i iz hrane, kao indikatorskog mikroorganizma za nivo rezistencije u našoj populaciji i da se utvrdi potencijalni put prenosa gena rezistencije na antibiotike. Materijal i metode. Ispitana je osetljivost po 50 izolata Escherichiae coli iz fecesa zdravih osoba izolovanih 2007. i 2010. godine i 50 izolata iz hrane. Za izolaciju i identifikaciju bakterija korišćene su standardne bakteriološke metode, a interpretacija rezultata antibiograma bila je u skladu sa Standardom iz 2010. godine. Rezultati. Markeri rezistencije nađeni su u svim ispitanim grupama Escherichiae coli. Svi izolati su najčešće bili rezistentni na ampicilin i kotrimoksazol, u 2010. godini nalaze se i multirezistentni sojevi i rezistencija na ciprofloksacin, a tipovi rezistencije izolata iz stolice i hrane su vrlo slični. Zaključak. Nalaz rastuće rezistencije na antimikrobne lekove, kako kod ešerihije normalne crevne flore tako i kod izolata iz hrane, pokazuje da je potrebno razviti sistem kontinuiranog sveobuhvatnog praćenja rezistencije bakterija na antibiotike.

Ključne reči

Ešerihija koli; Mikrobiološka rezistencija na lekove; Bakterijska rezistencija na lekove + genetika; Antibiotici; Feces + mikrobiologija; Mikrobiologija hrane; Ljudi

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