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Medicinski podmladak
2016, vol. 67, br. 2, str. 85-87
jezik rada: srpski
vrsta rada: izvorni naučni članak
doi:10.5937/medpodm1602085J
Creative Commons License 4.0
Osetljivost sojeva grupe B streptokoka, izolovanih kod trudnica u Beogradu, na antibiotike
aUniverzitet u Beogradu, Medicinski fakultet
bUniverzitet u Beogradu, Medicinski fakultet, Institut za mikrobiologiju i imunologiju

Sažetak

Uvod: Streptokok grupe B je značajan humani patogen koji kolonizuje vaginu i jedan je od najznačajnijih izazivača rane neonatalne sepse i meningitisa. U mnogim zemljama se sprovode skrining trudnica i intrapartalna upotreba antibiotika. Rezistencija streptokoka grupe B na linkozamide (klindamicin) i makrolide predstavlja značajan problem jer su oni terapija drugog izbora kod alergije na penicilin. Cilj: Naš cilj je bio određivanje rezistencije streptokoka grupe B na antibiotike i detekcija fenotipova makrolidne rezistencije na uzorku dobijenom od trudnica na teritoriji Beograda. Materijal i metode: U istraživanje je uključeno 105 izolata. Uzorci vaginalnih briseva od trudnica iz porodilišta Ginekološko- akušerske klinike 'Narodni front' i Ginekološko-akušerske klinike Kliničkog centra Srbije presejavani su na krvni i Miler Hinton agar radi daljih bakterioloških analiza i izrade antibiograma. Rezultati: Rezistencija na makrolide nađena je kod 30,4% izolata, a na klindamicin kod 23,8%. Nađena je velika učestalost rezistencije na tetracikline (88,6%). Dominantan fenotip rezistencije je bila izazvana udružena rezistencija na makrolide i linkozamide (MLS) (62,4%). Zaključak: Velika učestalost makrolidne rezistencije kod nas ukazuje na značaj daljeg praćenja ove pojave kod streptokoka grupe B.

Ključne reči

Streptokok grupe B; makrolidna rezistencija; trudnice

Reference

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