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Srpski arhiv za celokupno lekarstvo
2013, vol. 141, br. 1-2, str. 116-120
jezik rada: srpski
vrsta rada: prikaz
doi:10.2298/SARH1302116D


Polni dimorfizam i specifičnosti psihofarmakoterapijskog režima kod žena
aMedicinski fakultet, Beograd + Institut za mentalno zdravlje, Beograd
bUniverzitet u Beogradu, Medicinski fakultet, Institut za mentalno zdravlje

e-adresa: sagomat@eunet.rs

Sažetak

Polno specifične različitosti koje su uočene kod osoba obolelih od mentalnih poremećaja su značajan izvor razumevanja uticaja polnih hormona na funkciju mozga i ponašanje. Polni dimorfizam uočava se u prevalenciji i pojavi određenih mentalnih poremećaja kod žena, fenomenologiji i specifičnosti lečenja, odnosno odgovora na primenjenu psihofarmakoterapiju. Uzajamno zavisna veza hormona i biogenih amina povezuje se s razvojem različitih psihopatoloških ispoljavanja u biološki osetljivijim životnim ciklusima žena. Tako je povezanost polnih hormona i serotonergičke funkcije značajna za pojavu promena raspoloženja i afektivnih poremećaja u premenstrualnom i postpartalnom periodu. Specifičnosti neuroendokrine disregulacije, polno određene, uslovljavaju i moduliraju i specifičnosti u ispoljavanju nekih psihopatoloških stanja koja su svojstvena isključivo osobama ženskog pola. U radu se prikazuju i diskutuju podaci iz literature u vezi sa specifičnošću psihofarmakoterapijskog režima u određenim biološkim periodima žena (menopauza) i mentalnih poremećaja koji su povezani s ovim periodima (premenstrualni sindrom, postpartalni poremećaji).

Ključne reči

Reference

Abel, K.M., Drake, R., Goldstein, J.M. (2010) Sex differences in schizophrenia. International Review of Psychiatry, 22(5): 417-428
Agius, M., Hockings, H., Wilson, C., Lane, D. (2009) Is oestrogen neuroprotective ?. Psychiatr Danub, Suppl 1
Akiskal, H.S. (2009) Mood disorders: Introduction and overview. u: Kaplan H.I. i Sadock B.J. [ur.] Comprehensive textbook of psychiatry, New York-Philadelphia, itd: Lippincott, 1067-79
Berga, S.L., Parry, B.L., Moses-Kolko, E.L. (2009) Psychiatry and reproductive medicine. u: Kaplan H.I.; Sadock B.J. [ur.] Comprehensive Textbook of Psychiatry, Philadelphia: Lippincott Wiliams & Wilkins, 9th ed.; 2539-2562
Bigos, K.L., Pollock, B.G., Stankevich, B.A., Bies, R.R. (2009) Sex differences in the pharmacokinetics and pharmacodynamics of antidepressants: An updated review. Gender Medicine, 6(4): 522-543
Bower, B. (1996) Exploring trauma's cerebral side. Science News, 149, str. 315
Bremner, J.D., Randall, P., Scott, T.M., Bronen, R.A., Seibyl, J.P., Southwick, S.M., Delaney, R.C., McCarthy, G., Charney, D.S., Innis, R.B. (1995) MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry, 152(7): 973-81
Bukh, J.D., Bock, C., Vinberg, M., Gether, U., Kessing, L.V. (2010) Gender Differences among Patients with a Single Depressive Episode. Psychopathology, 43(3): 159-169
Burt, V.K., Rasgon, N. (2004) Special considerations in treating bipolar disorder in women. Bipolar Disorders, 6(1): 2-13
Cunningham, J., Yonkers, K.A., OʼBrien, S., Eriksson, E. (2009) Update on Research and Treatment of Premenstrual Dysphoric Disorder. Harvard Review of Psychiatry, 17(2): 120-137
Dickerson, L.M., Mazyck, P.J., Hunter, M.H. (2003) Premenstrual syndrome. Am Fam Physician, 65(8): 1743-1752
Draganić-Gajić, S., Lečić-Toševski, D., Švrakić, D., Paunović, V.R., Cvejić, V., Cloninger, R. (2008) Psihosomatski koncept Gravesove bolesti - bihevioralne i biohemijske karakteristike. Medicinski pregled, vol. 61, br. 7-8, str. 383-388
Draganić-Gajić, S., Lečić-Toševski, D., Paunović, V.R., Cvejić, V., Švrakić, D. (2005) Psihobiološki profil ličnosti obolelih od paničnog poremećaja. Srpski arhiv za celokupno lekarstvo, vol. 133, br. 3-4, str. 129-133
Fava, M., Abraham, M., Alpert, J., Nierenberg, A.A., Pava, J.A., Rosenbaum, J.F. (1996) Gender differences in Axis I comorbidity among depressed outpatients. Journal of affective disorders, 38(2-3): 129-33
Frey, B.N., Skelin, I., Sakai, Y., Nishikawa, M., Diksic, M. (2010) Gender differences in α-[11C]MTrp brain trapping, an index of serotonin synthesis, in medication-free individuals with major depressive disorder: A positron emission tomography study. Psychiatry Research: Neuroimaging, 183(2): 157-166
Garcia-Segura, L.M., Cardona-Gomez, P., Naftolin, F., Chowen, J.A. (1998) Estradiol upregulates Bcl-2 expression in adult brain neurons. NeuroReport, 9(4): 593-597
Goodnick, P.J., Chaudry, T., Artadi, J., Arcey, S. (2000) Women’s issues in mood disorders. Expert Opinion on Pharmacotherapy, 1(5): 903-916
Graziottin, A., Serafini, A. (2009) Depression and the menopause: why antidepressants are not enough?. Menopause International, 15(2): 76-81
Halbreich, U., Kahn, L.S. (2001) Role of Estrogen in the Aetiology and Treatment of Mood Disorders. CNS Drugs, 15(10): 797-817
Hallonquist, J.D., Seeman, M.V., Lang, M., Rector, N.A. (1993) Variation in symptom severity over the menstrual cycle of Schizophrenics. Biological Psychiatry, 33(3): 207-209
Harris, D.S., Wolkowitz, O.M., Reus, V.I. (2009) Psychoneuroendocrinology. u: Kaplan H.I., Sadock B.J. [ur.] Comprehensive Textbook of Psychiatry, Philadelphia: Lippincott Wiliams & Wilkins, str. 163-77
Hirschfeld, R.M.A., Weissman, M.M. (2002) Risk factors for major depression and bipolar disorder. u: Davis K.L., Charney D., Coyle J.T., Nemeroff C. [ur.] Psychopharmacology: The Fifth Generation of Progress, Philadelphia: Lippincott Wiliams & Wilkins, str. 1017-27
Horowitz, J.L., Garber, J. (2006) The prevention of depressive symptoms in children and adolescents: A meta-analytic review. Journal of Consulting and Clinical Psychology, 74(3): 401-415
Keers, R., Aitchison, K.J. (2010) Gender differences in antidepressant drug response. International Review of Psychiatry, 22(5): 485-500
Kemp, B., Bongartz, K., Rath, W. (2003) Psychic disturbances in the postpartum period: an increasing problem?. Zeitschrift für Geburtshilfe und Neonatologie, 207(5): 159-65
Knöchel, C., Oertel-Knöchel, V., Schönmeyer, R., Rotarska-Jagiela, A., van de Ven, V., Prvulovic, D., Haenschel, C., Uhlhaas, P., Pantel, J., Hampel, H., Linden, D.E.J. (2012) Interhemispheric hypoconnectivity in schizophrenia: Fiber integrity and volume differences of the corpus callosum in patients and unaffected relatives. NeuroImage, 59(2): 926-934
Kokras, N., Dalla, C., Papadopoulou-Daifoti, Z. (2011) Sex differences in pharmacokinetics of antidepressants. Expert Opinion on Drug Metabolism & Toxicology, 7(2): 213-226
Kornstein, S.G., Schatzberg, A.F., Yonkers, K.A., Thase, M.E., Keitner, G.I., Ryan, C.E., Schlager, D. (1995) Gender differences in presentation of chronic major depression. Psychopharmacology bulletin, 31(4): 711-8
Kulkarni, J. (2009) Oestrogen - a new treatment approach for schizophrenia?. Med J Aust., Suppl
Kulkarni, J., Gurvich, C., Lee, S.J., Gilbert, H., Gavrilidis, E., de Castella, A., Berk, M., Dodd, S., Fitzgerald, P.B., Davis, S.R. (2010) Piloting the effective therapeutic dose of adjunctive selective estrogen receptor modulator treatment in postmenopausal women with schizophrenia. Psychoneuroendocrinology, 35(8): 1142-1147
Lečić-Toševski, D., Draganić-Gajić, S., Šušić, V. (2006) Stres i rađanje. u: Kako zaustaviti belu kugu u Srbiji - uloga zdravstvene službe, Beograd: Srpska akademija nauka i umetnosti, 103-119
Lečić-Toševski, D.M., Draganić-Gajić, S., Vuković, O., Stepanović, J.M. (2001) Stres i telesne bolesti. Psihijatrija danas, vol. 33, br. 3-4, str. 149-173
Leibenluft, E., Hardin, T.A., Rosenthal, N.E. (1995) Gender differences in seasonal affective disorder. Depression, 3(1-2): 13-19
Macqueen, G., Chokka, P. (2004) Special issues in the management of depression in women. Can J Psychiatry, Suppl 1
Marganti, S., Ceda, G.P., Saccani, M., i dr. (2005) Thyroid disease in the elderly: Sex-related differences in clinical expression. J Endocrinol Invest, 28(Suppl 11 Proceedings): 101-4
Milovanovic, S., Djurić, D., Damjanović, A. (2009) Depresija - faktori rizika za nastanak kod žena. u: Ilić K., Tasić Lj. [ur.] Zdravlje žena u Srbiji, Beograd: Farmaceutski fakultet, str. 329-39
Parry, B.L., Berga, S.L. (2005) Premenstrual dysphoric disorder. u: Kaplan H.I.; Sadock B.J. [ur.] Comprehensive Textbook of Psychiatry, Philadelphia: Lippincott Wiliams & Wilkins, 8th ed.; 2315-2322
Post, R.M., Altshuler, L.L. (2009) Mood disorders: Treatment of bipolar disorder. u: Kaplan H.I., Sadock B.J. [ur.] Comprehensive Textbook of Psychiatry, Philadelphia: Lippincott Wiliams & Wilkins, str. 1744-813
Rasgon, NL., Hendrick, V.C., Garrick, T.R. (2009) Endocrine and metabolic disease. u: Kaplan H.I.; Sadock B.J. [ur.] Comprehensive Textbook of Psychiatry, Philadelphia: Lippincott Wiliams & Wilkins, 9th ed.; 2304-2314
Rubinow, D.R., Schmidt, P.J. (2009) Reproductive hormonal therapy: theory and practice. u: Kaplan H.I.; Sadock B.J. [ur.] Comprehensive Textbook of Psychiatry, Philadelphia: Lippincott Wiliams & Wilkins, 9th ed.; 3328-3334
Sagud, M., Hotujac, L., Mihaljević-Peles, A., Jakovljević, M. (2002) Gender differences in depression. Collegium antropologicum, 26(1): 149-57
Schmahl, C.G., Vermetten, E., Elzinga, B.M., Bremner, D. (2003) Magnetic resonance imaging of hippocampal and amygdala volume in women with childhood abuse and borderline personality disorder. Psychiatry Research: Neuroimaging, 122(3): 193-198
Sharma, V. (2003) Pharmacotherapy of postpartum psychosis. Expert Opinion on Pharmacotherapy, 4(10): 1651-1658
Soares, C.N., Poitras, J.R., Prouty, J. (2003) Effect of Reproductive Hormones and Selective Estrogen Receptor Modulators on Mood during Menopause. Drugs & Aging, 20(2): 85-100
Svrakic, D.M., Draganic, S., Hill, K., Bayon, C., Przybeck, T.R., Cloninger, C.R. (2002) Temperament, character, and personality disorders: etiologic, diagnostic, treatment issues. Acta Psychiatrica Scandinavica, 106(3): 189-195
Tosevski, D.L., Milovancevic, M.P. (2006) Stressful life events and physical health. Current opinion in psychiatry, 19(2): 184-9
Vermeiden, M., van den Broek, W., Mulder, P., Birkenhager, T. (2010) Influence of gender and menopausal status on antidepressant treatment response in depressed inpatients. Journal of Psychopharmacology, 24(4): 497-502
Whybrow, P.C. (1995) Sex differences in thyroid axis function: Relevance to affective disorder and its treatment. Depression, 3(1-2): 33-42
Yang, S., Kim, S., Stewart, R., Kim, J., Shin, I., Jung, S., Lee, M., Jeong, S., Jun, T. (2011) Gender differences in 12-week antidepressant treatment outcomes for a naturalistic secondary care cohort: The CRESCEND study. Psychiatry Research, 189(1): 82-90
Zukov, I., Ptácek, R., Raboch, J., Domluvilová, D., Kuzelová, H., Fischer, S., Kozelek, P. (2010) Premenstrual dysphoric disorder--review of actual findings about mental disorders related to menstrual cycle and possibilities of their therapy. Prague medical report, 111(1): 12-24