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Medicinski pregled
2011, vol. 64, br. 9-10, str. 481-485
jezik rada: srpski
vrsta rada: stručni članak
doi:10.2298/MPNS1110481M


Zastupljenost vankomicin rezistentnih enterokoka izolovanih iz hemokultura u periodu 2008-2010. godine
Institut za javno zdravlje Vojvodine, Centar za mikrobiologiju, Novi Sad

e-adresa: mikrobiologija@izjzv.org.rs

Sažetak

Zbog visoke zastupljenosti rezistencije na vankomicin i druge antibiotike, enterokoke se nalaze među vodećim uzročnicima bolničkih infekcija. Cilj rada je bio da se utvrdi prisustvo i učestalost rezistencije na vankomicin i druge najčešće korišćene antibiotike enterokoka izolovanih iz hemokultura. Osetljivost na antibiotike 132 soja Enterococcus spp. izolovana u periodu 2008-2010. godine ispitana je pomoću disk difuzione metode prema preporukama Clinical and Laboratory Standards Institute i automatizovanog VITEK sistema. Rezistencija se kretala od 15,9% na vankomicin do 81,3% na ciprofloksacin. Vankomicin rezistentne enterokoke, ispitane pomoću VITEK sistema, pripadale su vrsti Enteroccocus faecium i fenotipu VanA. Njihova rezistencija na ostale antibiotike bila je izrazito visoka, osim na quinupristin/dalfopristin i linezolid (4,7%). Od 21 soja, devet je bilo osetljivo samo na ove antibiotike. Visoko učešće multirezistentnih sojeva, osetljivih samo na quinupristin/dalfopristin i linezolid, od posebnog je značaja, što zahteva dalje praćenje osetljivosti i preduzimanje mera za kontrolu i prevenciju pojave i širenja rezistentnih sojeva.

Ključne reči

Rezistencija na Vankomicin; Enterococcus; Enterococcus faecalis; Enterococcus faecium; Krv + mikrobiologija; Bolničke infekcije; Rezistencija na lekove, mikrobna

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