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Medicinski pregled
2017, vol. 70, iss. 3-4, pp. 99-106
article language: English
document type: Professional Paper

Antimicrobial susceptibility pattern of Acinetobacter spp in the period 2012 - 2015
University of Novi Sad, Faculty of Medicine, Department of Infectious Diseases + Clinical Center of Vojvodina, Novi Sad, Clinic of Infectious Diseases



Introduction. Representatives of the genus Acinetobacter have become an important cause of hospital-acquired infections due to their great ability to survive and spread in a hospital environment, as well as rapid development of resistance to many antibiotics. The aim of this study was to determine the incidence of nosocomial infections caused by Acinetobacter spp among patients hospitalized at the Clinic of Infectious Diseases of the Clinical Center of Vojvodina; determine the presence and prevalence of resistance to antimicrobials in strains Acinetobacter spp, isolated from patient materials routinely sampled at the Clinic of Infectious Diseases of the Clinical Center of Vojvodina in the period January 1, 2012 to December 31, 2015. Material and Methods. A retrospective study included 1.673 patients with infectious diseases of bacterial etiology treated at the Clinic of Infectious Diseases of the Clinical Center of Vojvodina. The analysis of blood cultures, urine, cerebrospinal fluid culture, wound/decubitus swab, throat swabs, cannula/ tube swabs, and bronchial aspirate was performed to establish the incidence of infections caused by Acinetobacter spp and antimicrobial resistance. Results. During the four-year research, Acinetobacter spp was isolated from blood samples in 14/260 (5.4%), urine in 6/198 (3.0%), cerebrospinal fluid in 2/43 (4.7%), wound/decubitus swabs in 33/128 (25.8%), throat swabs in 14/124 (11.3%) cannula/ tube swabs and bronchial aspirate in 32/72 (44.4%) samples. The isolates of Acinetobacter spp showed the highest susceptibility to colistin (100%). Resistance to carbapenems and piperacillin/tazobactam accounted for nearly 100% in all tested isolates, while resistance to other antibiotics was over 63.6%, except to tobramycin whose resistance accounted for 11.1%. Conclusion. Representatives of the genus Acinetobacter are a common cause of nosocomial infections in hospitalized patients. Acinetobacter spp is only sensitive to colistin (100%), while it is resistant in various percentages to all other tested antibiotics.
For this article there is a related paper (correction, retraction, or comment) which is available here.



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