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Journal of Medical Biochemistry
2017, vol. 36, br. 2, str. 153-162
jezik rada: engleski
vrsta rada: izvorni članak
objavljeno: 28/01/2020
PMC ID: PMC5471648
doi: 10.1515/jomb-2017-0006
Skrining hroničnih bubrežnih bolesti kod odraslih muškaraca u Vojvodini - studija preseka
aUniverzitet u Novom Sadu, Medicinski fakultet + Klinički centar Vojvodine, Centar za laboratorijsku medicinu, Novi Sad
bKlinički centar Vojvodine, Centar za laboratorijsku medicinu, Novi Sad
cInstitute of Occupational Health, Novi Sad
dUniverzitet u Novom Sadu, Fakultet tehničkih nauka

e-adresa: velibor.cabarkapa@mf.uns.ac.rs

Projekat

This work was supported by grant No 114-451-1809/2014 approved by the Provincial Secretariat for Science and Technological Development, Autonomous Province of Vojvodina, Republic of Serbia.
Novi proizvodi cerealija i pseudocerealija iz organske proizvodnje (MPNTR - 46005)

Sažetak

Uvod: Hronične bolesti bubrega (HBB) jedan su od najznačajnijih zdravstvenih problema širom sveta, s obzirom na stalan porast broja obolelih, kao i zbog toga što su praćene brojnim komplikacijama. U odnosu na odmakle stadijume, u početnim je broj obolelih višestruko veći a tok je uglavnom asimptomatski, te je od presudnog značaja pravovremeno otkrivanje HBB. Cilj je bio ispitivanje prevalence HBB u opštoj populaciji odraslih muškaraca u Vojvodini, na osnovu procenjene jačine glomerulske filtracije (eJGF) i odnosa albumin/kreatinin u urinu (ACR), kao i ispitivanje determinanti HBB i svesnosti o postojanju HBB. Metode: U ovu studiju preseka uključeno je 3060 muških ispitanika iz opšte populacije, starijih od 18 godina, kod kojih je vršeno izračunavanje eJGF i ACR, pregled prvog jutarnjeg urina, merenje arterijskog krvnog pritiska, kao i izračunavanje indeksa telesne mase. Standardnim biohemijskim metodama određivane su serumske koncentracije kreatinina, uree, mokraćne kiseline i glukoze, kao i nivo albumina i kreatinina u urinu. Rezultati: U populaciji odraslih muškaraca zastupljenost HBB iznosi 7,9% i najviša je kod starijih od 65 godina (46,7% ), dok u ostalim starosnim grupama iznosi 3 ,6 -1 2 ,6 % . Najveći broj ispitanika sa pozitivnim markerima HBB boluje od hipertenzije i dijabetes melitusa. Samo je 1,3% ispitanika sa eJG F< 60 ml/mi/1,73 m2 i/ili ACR> 3 mg/mmol znalo da ima pozitivne biomarkere HBB. Zaključak: Dobijeni rezultati ukazuju da prevalenca HBB kod odraslih muškaraca u Vojvodini iznosi 7,9%, da su HTA i DM najznačajniji faktori rizika za HBB, te da je izrazito niska svest o postojanju HBB (1,3%), što ukazuje na neophodnost preduzimanja mera za prepoznavanje bolesti u ranom stadijumu, uključujuci i podizanje svesti o HBB.

Ključne reči

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