As a free and potentially toxic substances, solid and liquid manures of domestic livestock production are favorable digestate of small and large biogas plants. Vojvodina has a great potential of solid and liquid manure, as well as biomass in the form of resources for cogeneration of biogas into electrical and thermal energy. In accordance to that, as well as the increasing tendency of the need to heat and electricity, efficiency of the mentioned resources is low. Biogas production stabilizes manure. Thereby, for the most part, methane and carbon dioxide are emitted. Effluent, like the rest of the fermentation, contains approximately the same, but significantly easier adoptable form of nitrogen for plant life compared to raw manure. Controlled production of biogas, with its efficient use, provides features: environmental protection, suitable alternative energy resources, and thus significant support to national economy development of rural areas. The high capital investment for the formation of larger cogeneration biogas plant in Serbia necessitate the development of smaller digester systems, as integral parts of cattle, swine and poultry medium capacity farms.