Given the fact that the primary objective of Religious Education classes is the education and upbringing of a child, creating personal and universal social human values, spiritually enhancing the child’s personality, Religious Education is observed as a specific and complex subject, potentially unlimited in the scope of teaching contents. Namely, in addition to transposing the didactically shaped theological knowledge, Religion classes also enable acquiring the knowledge and understanding of the universe. In that context, the authors of this paper discuss the possibility of correlating the contents of Religion classes with the Literature classes in schools in order to spiritualize the personalities of children and the youth, particularly given the fact that literature is deeply rooted in religious books, such as the Bible as 'the Book above all books', and finds its source in the biblical context and subtext. Therefore, the authors points out to the inter-subject correlation between the Religion classes and the Literature classes, providing several examples on the correlation and integration of contents within these two subjects in both elementary and secondary school.