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Acta medica Medianae
2008, vol. 47, br. 3, str. 28-34
jezik rada: srpski
vrsta rada: izvorni naučni članak
objavljeno: 14/01/2009
Primena beta blokatora u akutnom koronarnom sindromu u Srbiji u periodu od 2000. do 2005. godine
Hemofarm AD, Beograd

e-adresa: Radovic@hemofarm.com

Sažetak

Pristupi u prevenciji i terapiji akutnog koronarnog sindroma (AKS) su razni modaliteti konzervativnih i invazivnih procedura, koji su doprineli da se poslednjih 20 godina, u mnogim delovima sveta, mortalitet od ishemijske bolesti srca (IBS) smanjio za oko 20%. Značajan doprinos tome dali su beta blokatori (BB), naročito njihova primena u AKS i prvim godinama sekundarne prevencije IBS. Cilj rada bila je procena bolesnika sa AKS u Srbiji u periodu od 2000. do 2005. godine, kao i procena primene BB u AKS i otklanjanje nedoumica vezanih za njihovo propisivanje. Podaci o obolelima dobijeni su iz Nacionalnog registra za AKS (REAKS) u Srbiji. U proteklom periodu zapažen je porast broja koronarnih jedinica (KJ) i porast obolelih od AKS. U prijemnim dijagnozama bilo je najviše bolesnika sa AIM ili 69,7%, gde je zabeležen i najveći ukupan mortalitet od 11,7%. Uočena je veća zastupljenost obolelih muškaraca u odnosu na obolele žene i to porast obolelih muškaraca u starosnoj grupi od 50 do 59 godina i porast obolelih žena u starosnoj grupi od 70 do 79 godina. Interesantna je velika zastupljenost ženskog pola, veća nego što se navodi u literaturi. Zapaženo je da se registruje značajno češća zastupljenost AIM sa elevacijom ST segmenta (STEMI), u odnosu na AIM bez ST elevacije (NSTEMI). STEMI je češći kod mlađih bolesnika i kod muškaraca. Letalitet bolesnika sa STEMI je značajno veći u odnosu na bolesnike NSTEMI (P<0,000). Procenat bolesnika sa AKS koji je primao BB i dalje je mali i nije se značajno menjao poslednjih godina.

Ključne reči

beta blokatori (BB); akutni koronarni sindrom (AKS); sekundarna prevencija ishemijske bolesti srca (IBS)

Reference

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