Metrika članka

  • citati u SCindeksu: 0
  • citati u CrossRef-u:0
  • citati u Google Scholaru:[=>]
  • posete u poslednjih 30 dana:3
  • preuzimanja u poslednjih 30 dana:3
članak: 1 od 3  
Back povratak na rezultate
Timočki medicinski glasnik
2014, vol. 39, br. 1, str. 14-20
jezik rada: srpski
vrsta rada: originalan članak
doi:10.5937/tmg1401014J


Efekti intra i postoperativne primene steroidnih injekcija kod operacija pterigijuma
aKlinika za oftalmologiju, Klinički centar Kragujevac
bUniverzitet u Kragujevcu, Medicinski fakultet

e-adresa: mira.andreja@yahoo.com

Sažetak

Uvod: Pterigijum je degenerativno oboljenje konjunktive sa afekcijom rožnjače oka. Svrha: Cilj rada je da se utvrdi efekat intra i postoperativne primene steroida u tretmanu primarnog i rekurentnog pterigijuma sa intralezionom aplikacijom subkonjunktivalnih injekcija. Metode: U studiju je uključeno 62 pacijenta (79 očiju) sa primarnim pterigijumom, i 57 pacijenata (64 oka) sa rekurentnim pterigijumom. Aplikacije: Triamcinolon-acetonida (Kenalog-40) kod operacija pterigijuma vršene su u našoj Klinici za oftalmologiju od 3. maja 2010. do 3. maja 2013. Pre i postoperativno aplikovane su dve do tri subkonjunktivalne injekcije steroida sa kliničkim praćenjem i evaluacijom kliničkih znakova regresije primarnog i rekurentnog pterigijuma, a u korelaciji sa kontrolnom grupom. Rezultati: Kod svih naših ispitanika došlo je do kompletne rezolucije primarnog i rekurentnog pterigijuma. Rekurentni pterigijum se pojavljivao jedino kod očiju u kontrolnoj grupi, kao kompletni recidiv, kod kojih nije primenjena subkonjunktivalna steroidna terapija ni na jednoj od kontrola, nakon jednog, šest i dvanaest meseci. Zaključak: Za kompletnu rezoluciju primarnog i recidivantnog pterigijuma potrebna je primena jedna do dve intralezione, subkonjunktivalne steroidne injekcije.

Ključne reči

primarni pterigijum; rekurentni pterigijum; hirurški tretman; Triamcinolon-acetonid

Reference

*** (2008) Health quality Ontario, limbal stem cell transplantation: An evidence-based analysis. Ont Health Technol Assess Ser, 8(7), 1-58
Bianchi, E., Scarinci, F., Grande, C., Plateroti, R., Plateroti, P., Plateroti, A.M., Fumagalli, L., Capozzi, P., Feher, J., Artico, M. (2012) Immunohistochemical profile of VEGF, TGF-β and PGE₂ in human pterygium and normal conjunctiva: experimental study and review of the literature. International journal of immunopathology and pharmacology, 25(3): 607-15
Bradley, J.C., Yang, W., Bradley, R.H., Reid, T.W., Schwab, I.R. (2010) The science of pterygia. British journal of ophthalmology, 94(7): 815-20
Džunić, B., Jovanović, P., Veselinović, D., Petrović, A., Stefanović, I., Kovačević, I. (2010) Analysis of pathohistological characteristics of pterygium. Bosnian journal of basic medical sciences, 10(4): 307-13
Golu, T., Mogoantă, L., Streba, C.T., Pirici, D.N., Mălăescu, D., Mateescu, G.O., Muţiu, G. (2011) Pterygium: histological and immunohistochemical aspects. Romanian journal of morphology and embryology, 52(1): 153-8
Heindl, L.M., Cursiefen, C. (2010) Pterygium. Etiology, clinical aspects and novel adjuvant therapies. Der Ophthalmologe, 107(6): 517-20, 522-4
Hosseini, H., Nowroozzadeh, M.H., Salouti, R., Nejabat, M. (2012) Anti-VEGF therapy with bevacizumab for anterior segment eye disease. Cornea, 31(3): 322-34
Kaufman, S.C., Jacobs, D.S., Lee, W. B., Deng, S.X., Rosenblatt, M.I., Shtein, R.M. (2013) Options and Adjuvants in Surgery for Pterygium. Ophthalmology, 120(1): 201-208
Kheirkhah, A., Nazari, R., Safi, H., Ghassemi, H., Behrouz, M.J., Raju, V.K. (2013) Effects of intraoperative steroid injection on the outcome of pterygium surgery. Eye, 27(8): 906-914
Kheirkhah, A., Nazari, R., Nikdel, M., Ghassemi, H., Hashemi, H., Behrouz, M.J. (2011) Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft. American Journal of Ophthalmology, 152(5): 733-8
Lee, S., Go, J., Rhiu, S., Stulting, R., Lee, M., Jang, S., Lee, S., Kim, H.J., Chung, E.S., Kim, S., Seo, K.Y. (2013) Cosmetic regional conjunctivectomy with postoperative mitomycin C application with or without bevacizumab injection. American Journal of Ophthalmology, 156(3): 616-22.e3
Mauro, J., Foster, C. (2009) Pterygia: pathogenesis and the role of subconjunctival bevacizumab in treatment. Seminars in ophthalmology, 24(3): 130-4
Mohammed, I. (2011) Treatment of pterygium. Annals of African Medicine, 10(3): 197
Nava-Castañeda, A., Olvera-Morales, O., Ramos-Castellon, C., Garnica-Hayashi, L., Garfias, Y. (2013) Randomized, controlled trial of conjunctival autografting combined with subconjunctival bevacizumab for primary pterygium treatment: 1-year follow-up. Clinical and Experimental Ophthalmology, 42(3): 235-241
Said, D.G., Faraj, L.A., Elalfy, M.S., Yeung, A., Miri, A., Fares, U., Otri, A.M., Rahman, I., Maharajan, S., Dua, H.S. (2013) Intra-lesional 5 fluorouracil for the management of recurrent pterygium. Eye, 27(10): 1123-1129
Sekundo, W. (2010) Epidemiology of pterygium. A review. Der Ophthalmologe, 107(6): 514-6
Shenasi, A., Mousavi, F., Shoa-Ahari, S., Rahimi-Ardabili, B., Fouladi, R.F. (2011) Subconjunctival bevacizumab immediately after excision of primary pterygium: the first clinical trial. Cornea, 30(11): 1219-22
Teng, C.C., Patel, N.N., Jacobson, L. (2009) Effect of subconjunctival bevacizumab on primary pterygium. Cornea, 28(4): 468-70
Turan-Vural, E., Torun-Acar, B., Kivanc, S., Acar, S. (2011) The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery. Clinical ophthalmology (Auckland, N.Z.), 5: 881-5
Uçakhan, O.O., Kanpolat, A. (2006) Combined 'symmetrical conjunctival flap transposition' and intraoperative low-dose mitomycin C in the treatment of primary pterygium. Clinical and experimental ophthalmology, 34(3): 219-25
Viani, G.A., Fonseca, E.C., de Fendi, L.I., Rocha, E.M. (2012) Conjunctival Autograft Alone or Combined With Adjuvant Beta-Radiation? A Randomized Clinical Trial. International journal of radiation oncology, biology, physics, 82(3): e507-e511
Wu, P., Kuo, H., Tai, M., Shin, S. (2009) Topical bevacizumab eyedrops for limbal-conjunctival neovascularization in impending recurrent pterygium. Cornea, 28(1): 103-4
Xu, F., Li, M., Yan, Y., Lu, K., Cui, L., Chen, Q. (2013) A novel technique of sutureless and glueless conjunctival autografting in pterygium surgery by electrocautery pen. Cornea, 32(3): 290-5