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Vojnosanitetski pregled
2009, vol. 66, br. 5, str. 359-364
jezik rada: srpski
vrsta rada: originalan članak
doi:10.2298/VSP0905359R


Uticaj aklimatizacije na promene koncentracija enzima u serumu vojnika izloženih toplotnom stresu usled fizičkog napora
aVojnomedicinska akademija
bUniverzitet u Beogradu, Medicinski fakultet, Klinički centar Srbije

e-adresa: radakovicss@eunet.rs

Sažetak

Uvod/Cilj. Toplotni stres usled fizičkog napora čest je problem u vojsci. Cilj istraživanja bio je da se ispita promena koncentracije enzima u serumu vojnika izloženih toplotnom stresu usled fizičkog napora, kao i uticaj desetodnevne pasivne, odnosno aktivne aklimatizacije. Metode. Ispitivanjem je bilo obuhvaćeno 40 vojnika muškog pola, visoke aerobne sposobnosti, koji su bili izloženi fizičkom naporu submaksimalnog intenzitet: vojnici K grupe u termoneutralnoj sredini: 20º C, ili 16º C in WBGT (indeks vlažnog i globus termometra), a ostali u toploj sredini (40º C, 25º C WBGT), i to neaklimatizovani, ili nakon 10-dnevne pasivne ili aktivne aklimatizacije u klimatskoj komori. Fiziološko opterećenje određivano je preko timpanične temperature i frekvencije srčanog rada. Serumske koncentracije alanin aminotransferaze (ALT) i aspratat aminotransferaze (AST), laktat dehidrogenaze (LDH) i kreatin kinaze (CK) određivane su iz uzoraka krvi uzetih pre testa i odmah nakon testa. Rezultati. Fizički napor u toploj sredini izazvao je značajno povećanje koncentracije svih ispitivanih enzima u neaklimatizovanoj grupi: ALT (sa 42,5 ± 4,2 na 48,1 ± 3,75 U/L, p < 0,01), AST (sa 24,9 ± 5,1 na 33,4 ± 4,48 U/L, p < 0,01), LDH (sa 160,6 ± 20,2 na 195,7 ± 22,6 U/L, p < 0,001) i CK (sa 215,5 ± 91,2 na 279,1 ± 117,5 U/L, p < 0,05). Aklimatizovani ispitanici nisu pokazali značajne promene koncentracije ALT i AST ali je koncentracija CK značajno porasla. Koncentracija LDH porasla je značajno u svim grupama, bez obzira na toplotne uslove. Zaključak. Desetodnevna pasivna ili aktivna aklimatizacija u veštačkim uslovima kod utreniranih vojnika dovodi do ublažavanja porasta serumskih koncentracija ALT i AST, u toku toplotnog stresa. Do povećanja koncentracije CK i LDH dolazi usled fizičkog napora, bez dodatnog uticaja toplotnog stresa.

Ključne reči

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