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Acta medica Medianae
2011, vol. 50, br. 1, str. 5-10
Učestalost cervikalnih intraepitelialnih neoplazija i karcinoma kod žena sa bakterijskom vaginozom i bez bakterijske vaginoze
Janjić Zorana, Trajković Pop Zorana, Folić Miroslavb, Popović Jasminaa, Petrić Aleksandraa, Vukomanović Predraga
aKlinički centar Niš, Klinika za ginekologiju i akušerstvo
bUniverzitet u Kragujevcu, Fakultet medicinskih nauka

e-adresa: zoranjjanjic@yahoo.com
Ključne reči: bakterijska vaginoza; cervikalna neoplazija; polno prenosive bolesti; učestalost
Sažetak
Bakterijska vaginoza je jedan od najčešćih poremećaja vaginalnog ekosistema kod žena u reproduktivnoj fazi života. Prvi koncept patogeneze bakterijske vaginoze ukazuje da iz nepoznatog inicijalnog uticaja na ekosistem vagine dolazi do smanjenja koncentracije laktobacila, što za posledicu ima povišenje pH vaginalnog sekreta i razmnožavanje Gardnerele vaginalis i ostalih anaeroba. Cilj ovog istraživanja bio je da uporedi učestalost pojave cervikalne neoplazije kod žena sa i bez bakterijske vaginoze. Istraživanjem je obuhvaćeno 158 ispitanica, starosti od 18. do 51. godine, bolesnica Klinike za ginekologiju i akušerstvo u Nišu. Klinička obrada ispitanica je podrazumevala citološko, kolposkopsko i patohistološko ispitivanje. Bakterijska vaginoza je, osim detekcije 'clue cell' na nativnom preparatu, dijagnostikovana primenom ostalih Amselovih kriterijuma: prisustvo karakterističnog vaginalnog sekreta, pozitivnog amino testa, vrednosti pH vaginalnog sekreta iznad 4,5. Rezultati istraživanja su pokazali da je 23,42% ispitanica imalo bakterijsku vaginozu. Najveći procenat ispitanica sa bakterijskom vaginozom (24,32%) bio je u starosnoj grupi od 20 do 34 godine. U ispitivanoj populaciji je 7,59% ispitanica imalo pozitivan patohistološki nalaz. Broj urednih patohistoloških nalaza bio je statistički značajno manji kod ispitanica sa bakterijskom vaginozom (75,68%) u odnosu na ispitanice bez bakterijske vaginoze (97,52%), (χ2=16,28, p<0,001).
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O članku

jezik rada: srpski
vrsta rada: originalan članak
objavljen u SCIndeksu: 28.06.2011.

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