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2009, vol. 62, br. 3-4, str. 101-106
Jednokratna antibiotska profilaksa kod elektivnih carskih rezova
aKlinički centar Vojvodine, Klinika za ginekologiju i akušerstvo, Novi Sad
bUniverzitet u Novom Sadu, Medicinski fakultet, Zavod za farmakologiju, toksikologiju i kliničku farmakologiju
cBolnica 'Genesis', Novi Sad
dZdravstveni centar 'Veljko Vlahović', Vrbas

e-adresaZorg@neobee.net
Sažetak
U istraživanje je bilo uključeno ukupno 147 ispitanica (135 trudnica i 12 pacijentkinja koje nisu trudne). Sve ispitivane trudnice, planirane za operativno završavanje porođaja elektivnim carskim rezom, bile su podeljene u grupe u zavisnosti od vrste (ceftriakson, gentamicin i cefazolin) antibiotske profilakse koja im je ordinirana jednokratno. Kod svih pacijentkinja, praćen je klinički postoperativni tok i eventualna pojava infekcije. Određivanje koncentracije antibiotika, neposredno nakon operacije i 6 h nakon početka operativnog zahvata vršeno je kod pacijentkinja ispitivane (trudnice) i kontrolne grupe (žene koje nisu trudne). Kod ispitivane grupe pacijentkinja određivana je i koncentracija antibiotika iz plodove vode i iz krvi pupčanika novorođenčeta neposredno nakon odvajanja od majke. Ukupan broj infekcija u ispitivanim grupama bio je 5,18%. Izmerene prosečne koncentracije ordiniranih antibiotika posle operacije i 6 h posle aplikacije bile su iznad minimalne inhibitorne koncentracije. Ovim je dokazano da je postignuta antibiotska profilaksa jednokratnim režimom dovoljna da spreči mogućnost prodora patogenih mikroorganizama sa kože.
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O članku

jezik rada: srpski
vrsta rada: izvorni naučni članak
DOI: 10.2298/MPNS0904101G
objavljen u SCIndeksu: 07.07.2009.

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