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Acta medica Medianae
2011, vol. 50, br. 1, str. 5-10
jezik rada: srpski
vrsta rada: originalan članak
objavljeno: 28/06/2011
Učestalost cervikalnih intraepitelialnih neoplazija i karcinoma kod žena sa bakterijskom vaginozom i bez bakterijske vaginoze
aKlinički centar Niš, Klinika za ginekologiju i akušerstvo
bUniverzitet u Kragujevcu, Medicinski fakultet

e-adresa: zoranjjanjic@yahoo.com

Sažetak

Bakterijska vaginoza je jedan od najčešćih poremećaja vaginalnog ekosistema kod žena u reproduktivnoj fazi života. Prvi koncept patogeneze bakterijske vaginoze ukazuje da iz nepoznatog inicijalnog uticaja na ekosistem vagine dolazi do smanjenja koncentracije laktobacila, što za posledicu ima povišenje pH vaginalnog sekreta i razmnožavanje Gardnerele vaginalis i ostalih anaeroba. Cilj ovog istraživanja bio je da uporedi učestalost pojave cervikalne neoplazije kod žena sa i bez bakterijske vaginoze. Istraživanjem je obuhvaćeno 158 ispitanica, starosti od 18. do 51. godine, bolesnica Klinike za ginekologiju i akušerstvo u Nišu. Klinička obrada ispitanica je podrazumevala citološko, kolposkopsko i patohistološko ispitivanje. Bakterijska vaginoza je, osim detekcije 'clue cell' na nativnom preparatu, dijagnostikovana primenom ostalih Amselovih kriterijuma: prisustvo karakterističnog vaginalnog sekreta, pozitivnog amino testa, vrednosti pH vaginalnog sekreta iznad 4,5. Rezultati istraživanja su pokazali da je 23,42% ispitanica imalo bakterijsku vaginozu. Najveći procenat ispitanica sa bakterijskom vaginozom (24,32%) bio je u starosnoj grupi od 20 do 34 godine. U ispitivanoj populaciji je 7,59% ispitanica imalo pozitivan patohistološki nalaz. Broj urednih patohistoloških nalaza bio je statistički značajno manji kod ispitanica sa bakterijskom vaginozom (75,68%) u odnosu na ispitanice bez bakterijske vaginoze (97,52%), (χ2=16,28, p<0,001).

Ključne reči

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