Metrics

  • citations in SCIndeks: 0
  • citations in CrossRef:0
  • citations in Google Scholar:[]
  • visits in previous 30 days:4
  • full-text downloads in 30 days:0

Contents

article: 5 from 39  
Back back to result list
2019, vol. 76, iss. 3, pp. 278-283
Discrepancies between clinical and autopsy diagnosis of cause of death among psychiatric patients who died due to natural causes. A retrospective autopsy study
University of Belgrade, Faculty of Medicine, Institute of Pathology, Serbia

emaildramit@med.bg.ac.rs
Abstract
Background/Aim. Autopsy studies rarely investigate the causes of natural death in psychiatric population. The aim of this study was to examine the causes of death among the subjects with various psychiatric disorders in whom a clinical (pathoanatomical) autopsy was requested. Methods. The study group included 118 patients (65% men, 35% women, mean age 58.2 ± 13.6 years) with a psychiatric diagnosis, in whom a clinical autopsy was performed. We compared the distribution of causes of natural death among psychiatric patients and other patients, representatives of the general population who died of natural causes. We also analyzed the difference between clinical diagnoses of cause of death and the autopsy findings in psychiatric patients. Results. Psychiatric patients died earlier than the control group (58 vs. 69 years), usually due to the respiratory (46%) and cardiovascular diseases (37%). The most common diagnoses in psychiatric patients were organic psychoses and dementias (F00-F09) and schizophrenia and schizoaffective disorders (F20-F29). Majority of the patients (55%) died in general hospitals vs. specialized psychiatric hospitals (45%) due to somatic diseases. There was a significant difference in the distribution of causes of death compared to the control group in which the cardiovascular diseases dominated. Even in 64% of psychiatric patients there was a discrepancy between the clinical diagnosis of the cause of death and definite autopsy findings. Conclusion. The assessment of somatic diseases in psychiatric patients is insufficient, especially in specialized psychiatric hospitals. That leads to a significant discrepancy between clinical diagnosis of the cause of death and autopsy findings. Therefore, it is necessary to pay additional attention in diagnostics and treatment of somatic diseases in these patients to improve their health care.
References
Aalten, C.M., Samson, M.M., Jansen, P.A. (2006) Diagnostic errors; the need to have autopsies. Neth J Med, 64(6): 186-90
Alfsen, G., Mæhlen, J. (2012) The value of autopsies for determining the cause of death. Tidsskrift for Den norske legeforening, 132(2): 147-151
Almeida, O.P., Hankey, G.J., Yeap, B.B., Golledge, J., Norman, P.E., Flicker, L. (2014) Mortality among People with Severe Mental Disorders Who Reach Old Age: A Longitudinal Study of a Community-Representative Sample of 37892 Men. PLoS One, 9(10): e111882
Amaddeo, F., Tansella, M. (2010) Mortality among people with mental disorders. Epidemiologia e Psichiatria Sociale, 19(1): 1-3
Appleby, L., Thomas, S., Ferrier, N., Lewis, G., Shaw, J., Amos, T. (2000) Sudden unexplained death in psychiatric in-patients. British Journal of Psychiatry, 176(05): 405-406
Bassat, Q., Castillo, P., Alonso, P.L., Ordi, J., Menéndez, C. (2016) Resuscitating the Dying Autopsy. PLOS Medicine, 13(1): e1001927
Berren, M.R., Santiago, J.M., Zent, M.R., Carbone, C.P. (1999) Health Care Utilization by Persons With Severe and Persistent Mental Illness. Psychiatric Services, 50(4): 559-561
Bivanco-Lima, D., de Souza, S.I., Vannucchi, A.M.C., de Almeida, R.M.C.S. (2013) Cardiovascular risk in individuals with depression. Revista da Associação Médica Brasileira, 59(3): 298-304
Brown, S., Inskip, H., Barraclough, B. (2000) Causes of the excess mortality of schizophrenia. Br J Psychiatry, 177, str. 212-7
Chang, C., Hayes, R.D., Broadbent, M., Fernandes, A.C., Lee, W., Hotopf, M., Stewart, R. (2010) All-cause mortality among people with serious mental illness (SMI), substance use disorders, and depressive disorders in southeast London: a cohort study. BMC Psychiatry, 10(1):
Chang, C., Hayes, R.D., Perera, G., Broadbent, M.T. M., Fernandes, A.C., Lee, W.E., Hotopf, M., Stewart, R. (2011) Life Expectancy at Birth for People with Serious Mental Illness and Other Major Disorders from a Secondary Mental Health Care Case Register in London. PLoS One, 6(5): e19590
Colton, C.W., Manderscheid, R.W. (2006) Congruencies in increased mortality rates, years of potential life lost, and causes of death among public mental health clients in eight states. Prev Chronic Dis, 3(2)
Correll, C.U., Solmi, M., Veronese, N., Bortolato, B., Rosson, S., Santonastaso, P., Thapa-Chhetri, N., Fornaro, M., Gallicchio, D., Collantoni, E., Pigato, G., Favaro, A., Monaco, F., Kohler, C. (2017) Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls. World Psychiatry, 16(2): 163-180
Dembling, B.P., Chen, D.T., Vachon, L. (1999) Life Expectancy and Causes of Death in a Population Treated for Serious Mental Illness. Psychiatric Services, 50(8): 1036-1042
Druss, B.G., Bradford, W. D., Rosenheck, R.A., Radford, M.J., Krumholz, H.M. (2001) Quality of Medical Care and Excess Mortality in Older Patients With Mental Disorders. Archives of General Psychiatry, 58(6): 565
Grigoletti, L., Perini, G., Rossi, A., Biggeri, A., Barbui, C., Tansella, M., Amaddeo, F. (2009) Mortality and cause of death among psychiatric patients: a 20-year case-register study in an area with a community-based system of care. Psychological Medicine, 39(11): 1875
Ifteni, P., Correll, C.U., Burtea, V., Kane, J.M., Manu, P. (2014) Sudden unexpected death in schizophrenia: Autopsy findings in psychiatric inpatients. Schizophrenia Research, 155(1-3): 72-76
Lau, G. (2005) Iatrogenic Injury. in: Tsokos, Michael [ed.] Forensic Pathology Reviews, Totowa, NJ: Springer Science and Business Media LLC, : 351-439
Math, S., Shinde, S., Nagarajaiah,, Narayanaswamy, J., Viswanath, B., Kumar, N., Gangadhar, B. (2014) Mortality among inpatients of a psychiatric hospital: Indian perspective. Indian Journal of Psychological Medicine, 36(2): 142
o'Grady G. (2003) Death of the teaching autopsy. BMJ, 327(7418): 802-803
Okkels, N., Thygesen, N.B., Jensen, B., Wendelboe, M.H., Munk-Joergensen, P. (2013) 1086 - Barriers to somatic health care in psychiatric inpatient wards. European Psychiatry, 28: 1
Ringen, P.A., Engh, J.A., Birkenaes, A.B., Dieset, I., Andreassen, O.A. (2014) Increased Mortality in Schizophrenia Due to Cardiovascular Disease â€' A Non-Systematic Review of Epidemiology, Possible Causes, and Interventions. Frontiers in Psychiatry, 5: 137
Rosh, A., Sampson, B.A., Hirsch, C.S. (2003) Schizophrenia as a Cause of Death. Journal of Forensic Sciences, 48(1): 2002001
Ruschena, D., Mullen, P.E., Burgess, P., Cordner, S., Barry-Walsh, J., Drummer, O., Palmer, S., Browne, C., Wallace, C. (1998) Sudden death in psychiatric patients. British Journal of Psychiatry, 172(04): 331-336
Scordi-Bello, I.A., Kalb, T.H., Lento, P.A. (2010) Clinical setting and extent of premortem evaluation do not predict autopsy discrepancy rates. Modern Pathology, 23(9): 1225-1230
Sims, A. (2001) Mortality statistics in psychiatry. British Journal of Psychiatry, 179(06): 477-478
Swildens, W., Termorshuizen, F., de Ridder, A., Smeets, H., Engelhard, I.M. (2016) Somatic Care with a Psychotic Disorder. Lower Somatic Health Care Utilization of Patients with a Psychotic Disorder Compared to Other Patient Groups and to Controls Without a Psychiatric Diagnosis. Administration and Policy in Mental Health and Mental Health Services Research, 43(5): 650-662
van Hasselt, F.M., Schorr, S.G., Mookhoek, E.J., Brouwers, J.R. B. J., Loonen, A.J. M., Taxis, K. (2012) Gaps in health care for the somatic health of outpatients with severe mental illness. International Journal of Mental Health Nursing, 22(3): 249-255
Vreeland, B. (2007) Bridging the gap between mental and physical health: a multidisciplinary approach. J Clin Psychiatry, 68 Suppl 4: 26-33
Westman, J., Hällgren, J., Wahlbeck, K., Erlinge, D., Alfredsson, L., Ösby, U. (2013) Cardiovascular mortality in bipolar disorder: a population-based cohort study in Sweden. BMJ Open, 3(4): e002373
 

About

article language: English
document type: Original Scientific Paper
DOI: 10.2298/VSP170304132M
published in SCIndeks: 25/04/2019
peer review method: double-blind
Creative Commons License 4.0

Related records

No related records