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2019, vol. 147, iss. 9-10, pp. 567-570
Early and midterm results after surgical repair of anomalous origin of the left coronary artery from the pulmonary artery
aUniversity of Belgrade, Faculty of Medicine, Institute of Mother and Child Health Care 'dr Vukan Čupić' + University of Belgrade, Faculty of Medicine
bUniversity of Belgrade, Faculty of Medicine, Institute of Mother and Child Health Care 'dr Vukan Čupić'
cUniveristy of Niš, Faculty of Medicine + Clinical Centre Niš, Clinic of Children's Internal Diseases
dNovi Pazar General Hospital

emailvvukomanovicdr@gmail.com
Keywords: ALCAPA; cardiomyopathy; echocardiography
Abstract
Introduction/Objective The anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is rare congenital disease, which causes myocardial ischemia and subsequent heart failure in infants. The aim is early and mid-term follow up evaluation of the heart function after surgical repair of ALCAPA. Methods Investigation was retrospective and included medical records of the ALCAPA patients treated surgically, between 2009 and 2017, at the tertiary referent heart center. Results Five patients (four girls) with coronary anomaly were included in the study. All patients had significantly increased left ventricular end diastolic diameter (z-score 6.6 ± 2.43) and left atria size (z-score 3.09 ± 0.37), along with decreased systolic function (ejection fraction 34.8 ± 7.4% and fractional shortening 15.5 ± 3.4%). The surgery was performed on average at the age of 8.2 ± 7.8 months. Operative treatment was associated with early improvement in echocardiographic parameters (except the size of the left atria). Patients were followed for 4.5 ± 2.6 years. Improvement in echocardiographic parameters was age-related. Patients under four months had recovery early after surgery, those treated at 5.5-6 months of age had normalization after 12 months, and patient who was recognized in the second year of life had late recovery (after ≥ 24 months). Conclusion Operative treatment in the first 3-4 months of life is related with the most favorable prognosis and rapid normalization of the echocardiographic parameters.
References
Ali, B.W., Metton, O., Roubertie, F., Pouard, P., Sidi, D., Raisky, O., et al. (2009) Anomalus origin of the left coronary artery from pulmonary artery: Late results with special attention to the mitral valve. Eur J Cardiothorac Surg, 36(2), 244-249
Azar, N., Nasser, M., Sabban, M.E., Bitar, H., Obeid, M., Dbaibo, G.S., Bitar, F.F. (2003) Cardiac growth patterns in response to chronic hypoxia in a neonatal rat model mimicking cyanotic heart disease. Exp Clin Cardiol, 8(4), 189-194
Barretta, J.O. (2010) Anomalous origin of the left coronary artery from the pulmonary artery. Rev Argent Cardiol, 78, 393-394
Cabrera, A.G., Chen, D.W., Pignatelli, R.H., Khan, M.S., Jeewa, A., Mery, C.M. (2015) Outcomes of anomalous left coronary artery from pulmonary artery repair: Beyond normal function. Ann Thorac Surg, 99(4), 1342-1347
Dodge-Khatami, A., Mavroudis, C., Backer, L.C. (2002) Anomalous origin of the left coronary artery from the pulmonary artery: Collective review of surgical therapy. Ann Thorac Surg, 74(3), 946-955
Fratz, D., Hager, A., Schreiber, C., Schwaiger, M., Hess, J., Stern, H.C. (2011) Long-term myocardial scarring after operation for anomalous left coronary artery from the pulmonary artery. Ann Thorac Surg, 92(5), 1761-1766
Martinsen, B.J., Lohr, J.L. (2015) Cardiac development. in: Laizo A P [ed.] Handbook of cardiac anatomy, physiology and devices, Switzerland: Springer, 3rd edition, 29-31
Mollova, M., Bersell, K., Walsh, S., Savla, J., Das, L.T., Park, S.Y., et al. (2013) Cardiomyocyte proliferation contributes to heart growth in young humans. Proc Natl Acad Sci, 110(4), 1446-1451
Ojala, T., Salminen, J., Happonen, J.M., Pihkala, J., Jokinen, E., Sairanen, H. (2010) Excellent functional result in children after correction of anomalous origin of left coronary artery from the pulmonary artery: A population-based complete follow-up study. Interact Cardiovasc Thorac Surg, 10(1), 70-75
Pettersen, M.D., Du, W., Skeens, M.E., Humes, R.A. (2008) Regression equations for calculation of Z-scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: An echocardiographic study. J Am Soc Echocardiogr, 21(8), 922-934
Weigand, J., Marshall, C.D., Bacha, E.A., Chen, J.M., Richmond, M.E. (2015) Repair of anomalous left coronary artery from the pulmonary artery in the modern era: Preoperative predictors of immediate postoperative outcomes and long term cardiac follow-up. Pediatr Cardiol, 36(3), 489-497
Ye, L., Qiu, L., Zhang, H., Chen, H., Jiang, C., Hong, H., et al. (2016) Cardiomyocytes in young infants with congenital heart disease: A three-month window of proliferation. Sci Rep, 6, 23188-23188
Zoghbi, W.A., Adams, D., Bonow, R.O., Enriquez-Sarano, M., Foster, E., Grayburn, P.A., et al. (2017) Recommendations for noninvasive evaluation of native valvular regurgitation a report from the American Society of Echocardiography Developed in collaboration with the Society for Cardiovascular Magnetic Resonance. J Am Soc Echocardiogr, 30(4), 303-371
 

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article language: English
document type: Original Paper
DOI: 10.2298/SARH180730032P
published in SCIndeks: 16/11/2019

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