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2018, vol. 69, br. 2, str. 42-48
Pseudoeksfolijativni glaukom - uvek aktuelan problem u oftalmologiji
aUniverzitet u Beogradu, Medicinski fakultet
bUniverzitet u Beogradu, Medicinski fakultet + Klinički centar Srbije, Klinika za očne bolesti, Beograd

e-adresadolika.vasovic@gmail.com
Ključne reči: PEX sindrom; kapsularni glaukom; učestalost
Sažetak
Uvod: Pseudoeksfolijativni (PEX) sindrom nije samo bolest oka, već je i opšti poremećaj sa abnormalnom produkcijom i deponovanjem depozita ekstracelularnog matriksa u intra i ekstraokularnim tkivima. Povišen intraokularni pritisak u očima sa pseudoeksfolijacijama dovodi do glaukomatoznih oštećenja u toku dužeg vremena i to u većem stepenu nego u očima bez pseudoeksfolijacija. Prognoza je lošija kod pseudoeksfolijativnog (kapsularnog) glaukoma nego kod primarnog glaukoma otvorenog ugla. Cilj: Cilj ovog rada bio je da ispita prisustvo i učestalost kapsularnog glaukoma u odnosu na druge tipove glaukoma u bolesničkom materijalu u toku mesec dana ambulantnog praćenja i u ukupnom broju glaukomno operisanih bolesnika u protekloj godini. Materijal i metode: Ispitivanjem je obuhvaćeno 105 pacijenata koji su oftalmološki pregledani u toku novembra 2016. godine, dok je uvidom u operativni protokol obuhvaćen uzorak od 346 pacijenata kod kojih je glaukom operisan u periodu od januara do oktobra iste godine na Klinici za očne bolesti Kliničkog centra Srbije. U pregledu su korišćene metode: biomikroskopije, aplanacione tonometrije, kompjuterizovane perimetrije, oftalmoskopije, gonioskopije i Hajdelbergove tomografije retine II. Rezultati: Iako je učestalost kapsularnog glaukoma u našem uzorku bila češća kod žena 14 (13,4 %) u odnosu na muškarce 11 (10,4 %), statistički značajna razlika u odnosu na pol nije zapažena (p = 0,352). Rezultati naše studije govore da se binokularni oblik kapsularnog glaukoma javlja 3,7 puta češće od monokularnog oblika kod žena, dok je kod muškaraca binokularni oblik 1,7 puta češći u odnosu na monokularni. Od ukupnog broja operisanih, zastupljenost kapsularnog glaukoma u odnosu na ostale vrste glaukoma iznosila je 94 (27,2 %) što ukazuje da je svaki četvrti operisani bolesnik imao dijagnozu kapsularnog glaukoma. Zaključak: Na osnovu rezultata ove studije može se zaključiti da kapsularni glaukom, kao najznačajnija okularna manifestacija PEX sindroma, pokazuje veliku učestalost i u našoj populaciji. Obavljanje pažljivog oftalmološkog pregleda kod osoba starijih od 50. godina se savetuje radi rane dijagnostike i otkrivanja prisustva pseudoeksfolijacija u oku.
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O članku

jezik rada: srpski
vrsta rada: izvorni naučni članak
DOI: 10.5937/mp69-13875
objavljen u SCIndeksu: 13.07.2018.
metod recenzije: dvostruko anoniman
Creative Commons License 4.0