- citati u SCIndeksu: 0
- citati u CrossRef-u:0
- citati u Google Scholaru:[
 ]
- posete u poslednjih 30 dana:12
- preuzimanja u poslednjih 30 dana:9
|
|
|
2020, vol. 25, br. 79, str. 45-50
|
|
Hipotireoza kao uzrok erektilne disfunkcije
Sažetak
Uvod: Erektilna disfunkcija predstavlja značajan javno-zdravstveni problem. Smatra se da od iste stalno ili povremeno boluje više od 50% muškaraca u dobi od 40 do 70 godina. Prikaz slučaja: Pacijent starosti 45 godina dolazi u ambulantu porodične medicine zbog problema sa erekcijom unazad šest mjeseci. Navodi sveprisutniji izostanak jutarnje erekcije, noćne erekcije i spontane erekcije zadovoljavajuće za seksualni odnos. Negira tegobe u medicinskoj, seksualnoj i psihosocijalnoj anamnezi. Fizikalni pregled otkriva uvećanu štitnu žlijezdu. Ultrazvukom se nalazi nehomogen, mjestimično kalcifikovan, jasno ograničen nodus 24 x 30 x 22 mm u desnom režnju štitne žlijezde. Standardne laboratorijske analize verifikuju hipotireozu. Pacijent se upućuje specijalisti nuklearne medicine radi aspiracione biopsije nodusa i uvođenja supstitucione terapije. Citološki nalaz bioptata otkriva folikularne nakupine makronuklearnih tireocita hiperhromatskih jedara (TBSRTC IV folikulani tumor) te se indikuje desnostana lobektomija na koju pacijent pristaje. Patohistološki nalaz nakon operativnog zahvata isključuje postojanje maligne bolesti (struma multinodosa glandulae thyreoideae), te se pacijentu uključuje supstituciona terapija, levotiroksin natrijum 1x100 mcg. Šest mjeseci nakon učinjene lobektomije kontrolni pregled u ambulanti porodične medicine otkriva normalizaciju erektilne funkcije. Zaključak: Rana detekcija i pravovremeno liječenje poremećaja štitne žlijezde kod osoba sa erektilnom disfunkcijom mogu dovesti do značajnog poboljšanja i normalizacije erektilne funkcije.
Abstract
Introduction: Erectile dysfunction is a significant public health problem. It is estimated that more than 50% of men between the ages of 40 and 70 suffer from the same or intermittent illness. Case report: A 45 years old patient was admitted to the family medicine ambulance for erection problems over the previous 6 months He complained on the ubiquitous absence of morning erection, nocturnal erection and spontaneous erection satisfactory for sexual intercourse. Physical examination reveals an enlarged thyroid gland. Ultrasound detected a non-homogeneous, partially calcified, clearly circumscribed nodule 24 x 30 x 22 mm in the right lobe of the thyroid gland. A diagnosis of hypothyroidism was based on thyroid function test. The patient was referred to a nuclear medicine specialist for Fine needle aspiration biopsy. The cytological finding of the bioptate reveals follicular accumulations of macronuclear thyrocytes of hyperchromatic nuclei (TBSRTC IV follicular tumor) and right-sided lobectomy was performed. Levothyroxine therapy was initiated and six months after that erectile function was normalised. Conclusion: Early detection and adequate treatment of hypothyroidism in patients with erectile dysfunction could result in significant improvement in erectile function.
|
|
|
|
Reference
|
| |
Naknadno pridodat članak: provera, normiranje i linkovanje referenci u toku. |
|
|
Krassas GE, Tziomalos K, Papadopoulou F, Pontikides N, Perros P. Erectile Dysfunction in Patients with Hyperand Hypothyroidism: How Common and Should We Treat?. The Journal of Clinical Endocrinology & Metabolism.2008: 93 (5): 1815-1819. Dostupno na: https://doi.org/10.1210/jc.2007-2259
|
|
|
Katušić J, Štimac G, Čehok M. Erektilna disfunkcija: simptom ili bolest? Medix. 2011; 17 (96): 146-152. Available from: https://www.kardio.hr/wp-content/uploads/2012/02/146-152.pdf
|
|
|
Heidelbaugh JJ. Management of Erectile Dysfunction. Am Fam Physician. 2010; 81(3): 305-312. Available from: https://www.aafp.org/afp/2010/0201/p305.html
|
|
|
Gabrielson AT, Sartor RA, Hellstrom WJG. The Impact of Thyroid Disease on Sexual Dysfunction in Men and Women. Sex Med Rev 2019; 7 : 57-70. Available from: https://www.smr.jsexmed.org/article/S2050-0521(18)30059-3/pdf
|
|
|
Chen D, Yan Y, Huang H, Dong Q, Tian H. The association between subclinical hypothyroidism and erectile dysfunction. Pak J Med Sci. 2018; 34 (3): 621-625. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041544
|
|
|
Corona, G, Wu FCW, Forti G, Lee DM, O'Connor DB, O'Neill TW, Pendleton N, Bartfai G., Boonen S., Casanueva FF, Finn JD, Giwercman A, Han TS, Huhtaniemi IT, Kula, Lean MEJ, Punab M, Vanderschueren D, Jannini, EA, Mannucci E, Maggi M. Thyroid hormones and male sexual function. International Journal of Andrology. 2012; 35: 668-679. Available from: https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1365-2605.2012.01266.x
|
|
|
Carosa E, Di Sante S, Rossi S, Castri A, D'Adamo F, Gravina GL, et al. Ontogenetic profile of the expression of thyroid hormone receptors in rat and human corpora cavernosa of the penis. J Sex Med. 2010; 7: 1381-1390. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017743
|
|
|
Jandrić-Kočič M. Uloga hipotiroidizma u nastanku metaboličkog sindroma i hepatične steatoze. Medicinski glasnik Specijalne bolnice za bolesti štitaste žlezde i bolesti metabolizma 'Zlatibor'. 2019; 24(75): 47-56. Dostupno na: https://scindeks.ceon.rs/article.aspx?query=ISSID%26and%2614739&page=3&sort=8&stype=0&backurl=%2fissue.aspx%3fissue%3d14739
|
|
|
Anadi K, Sabo A, Sagay S. Thyroid hormone: the modulator of erectile function in the rabbit. Nigerian Journal of Physiological Sciences. 2006; 21 (1-2): 83-89. Available from: http://www.bioline.org.br/request?np06016
|
|
|
Simone Magagnin W, Márcia Santo W, Ana Luiza M. Clinical implications of altered thyroid status in male testicular function. Arq Bras Endocrinol Metab. 2009; 53(8): 976-982. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302009000800011&lng=en. https://doi.org/10.1590/S0004-27302009000800011
|
|
|
Krassas GE, Tziomalos K, Papadopoulou F, Pontikides N, & Perros P. Restoration of euthyroidism in hyperand hypothyroid patients improves erectile dysfunction. Journal of Clinical Endocrinology & Metabolism. 2008; 93: 1815-1819. Available from: https://www.thyroidmanager.org/2008/08/01/restoration-of-euthyroidism-in-hyper-and-hypothyroid-patients-improves-erectile-dysfunction
|
|
|
|
|