Metrika

  • citati u SCIndeksu: 0
  • citati u CrossRef-u:0
  • citati u Google Scholaru:[]
  • posete u poslednjih 30 dana:10
  • preuzimanja u poslednjih 30 dana:7

Sadržaj

članak: 3 od 15  
Back povratak na rezultate
2016, vol. 69, br. 1-2, str. 11-15
Upotreba lekova u lečenju bolesti štitaste žlezde tokom trudnoće u Srbiji
Univerzitet u Novom Sadu, Medicinski fakultet + Univerzitet u Novom Sadu, Medicinski fakultet, Zavod za farmakologiju, toksikologiju i kliničku farmakologiju

e-adresaolgahorvat15@gmail.com
Projekat:
Interakcije ksenobiotika i uticaj na sisteme u biomedicini (MPNTR - 41012)
Pokrajinskog sekretarijata za nauku i tehnološki razvoj AP Vojvodine br. 114-451-3551/2013-02

Ključne reči: Oboljenja štitne žlezde; Trudnoća; Hašimotova bolest; Hipotireoza; Propiltiouracil; Tiroksin; Faktori rizika; Terapija; Epidemiologija; Srbija
Sažetak
Uvod. Od zagađujućih supstancija, kao rezultat konfliktnih situacija na području Srbije, značajno mesto zauzimaju osiromašeni uranijum i polihlorovani bifenili koji, uz propratni dugotrajni stres, značajno utiču na funkciju štitaste žlezde. Cilj rada bio je da se odredi trend upotrebe lekova u terapiji bolesti štitaste žlezde tokom trudnoće na teritoriji grada Novog Sada. Materijal i metode. Tokom jednomesečnog perioda anketirane su sve porodilje hospitalizovane na Klinici za ginekologiju i akušerstvo 1989, 1999, 2007. i 2011. godine, o bolestima štitaste žlezde, kao i o tome koji lek uzimaju u terapiji poremećaja funkcije štitaste žlezde. Rezultati. Tokom 1989. i 1999. godine nijedna trudnica nije evidentirana sa poremećajem funkcije štitaste žlezde, 2007. godine evidentirane su 4 trudnice, a 2011. godine bilo je 18 trudnica sa poremećajem funkcije štitaste žlezde od čega čak 14 sa dijagnozom hipotiroze i to u najvećem broju slučaja kao autoimuni Hašimotov tiroiditis. Zaključak. Rezulati našeg rada ukazuju na neophodnost sprovođenja detaljnije analize povezanosti učestalosti ovih poremećaja funkcije štitaste žlezde i uticaja zagađivača životne sredine.
Reference
*** (2001) Final act of the Conference of Plenipotentiaries on the Stockholm Convention on persistent organic pollutants. New York, NY: United Nations Environment Programme, United Nations Enviroment Programme
*** (1999) The Kosovo conflict consequences for the environment & human settlements. UNEP/UNCHS Report, Geneva
*** (1992) Medication during pregnancy: An intercontinental cooperative study: Collaborative group on drug use in pregnancy (C.G.D.U.P.). Int J Gynaecol Obstet, [No authors listed], 39(3): 185-96
Abalovich, M., Amino, N., Barbour, L.A., Cobin, R.H., de Groot, L.J., Glinoer, D., i dr. (2011) Management of thyroid dysfunction during pregnancy and postpartum: An endocrine society clinical practice guideline. Eur J Intern Med, 22(4): 330-3
Ausó, E., Lavado-Autric, R., Cuevas, E., del Rey, F.E., de Escobar, G.M., Berbel, P. (2004) A Moderate and Transient Deficiency of Maternal Thyroid Function at the Beginning of Fetal Neocorticogenesis Alters Neuronal Migration. Endocrinology, 145(9): 4037-4047
Bikit, I., Slivka, J., Čonkić, Lj., Krmar, M., Vesković, M., Žikić-Todorović, N., Varga, E., Ćurčić, S., Mrđa, D. (2005) Radioactivity of the soil in Vojvodina (northern province of Serbia and Montenegro). J Environ Radioactivity, 78: 11-9
Bjoro, T., Holmen, J., Kruger, O., Midthjell, K., Hunstad, K., Schreiner, T., Sandnes, L., Brochmann, H. (2000) Prevalence of thyroid disease, thyroid dysfunction and thyroid peroxidase antibodies in a large, unselected population. The Health Study of Nord-Trondelag (HUNT). European Journal of Endocrinology, 143(5): 639-647
Bleise, A., Danesi, P., Burkart, W. (2003) Properties, use and health effects of depleted uranium (DU): a general overview. Journal of Environmental Radioactivity, 64(2-3): 93-112
Boas, M., Feldt-Rasmussen, U., Main, K.M. (2012) Thyroid effects of endocrine disrupting chemicals. Molecular and Cellular Endocrinology, 355(2): 240-248
Cardis, E., Kesminiene, A., Ivanov, V., Malakhova, I., Shibata, Y., Khrouch, V., Drozdovitch, V., Maceika, E., Zvonova, I., Vlassov, O. (2005) Risk of thyroid cancer after exposure to 131I in childhood. J Natl Cancer Inst, 97(10): 724-32
Chevrier, J., Eskenazi, B., Holland, N., Bradman, A., Barr, D.B. (2008) Effects of Exposure to Polychlorinated Biphenyls and Organochlorine Pesticides on Thyroid Function during Pregnancy. American Journal of Epidemiology, 168(3): 298-310
Cruz-Cruz, E.A., Ramírez-Torres, A., Pimentel-Nieto, D., Sánchez, R.A.M. (2014) Prevalence of clinical and subclinical hypothyroidism during pregnancy in a pregnant women population. Ginecol Obstet Mex, 82(11):717-24. [Article in Spanish]
Domingo, J.L. (2001) Reproductive and developmental toxicity of natural and depleted uranium: A review. Reprod Toxicol, 15(6): 603-9
Duraković, A. (2014) On depleted uranium: Gulf war and Balkan syndrome. 2(2): 130-4
Hagmar, L., Rylander, L., Dyremark, E., Klasson-Wehler, E., Erfurth, E.M. (2001) Plasma concentrations of persistent organochlorines in relation to thyrotropin and thyroid hormone levels in women. International Archives of Occupational and Environmental Health, 74(3): 184-188
Jacobson, J.L., Jacobson, S.W. (2002) Association of Prenatal Exposure to an Environmental Contaminant with Intellectual Function in Childhood. Journal of Toxicology: Clinical Toxicology, 40(4): 467-475
Langer, P., Tajtakova, M., Fodor, G., Kocan, A., Bohov, P., Michalek, J., Kreze, A. (1998) Increased thyroid volume and prevalence of thyroid disorders in an area heavily polluted by polychlorinated biphenyls. European Journal of Endocrinology, 139(4): 402-409
Langer, P., Kaušitz, J., Tajtáková, M., Kočan, A., Bohov, P., Hanzen, E. (1997) Decreased blood level of β2-microglobulin in the employees of a factory which produced polychlorinated biphenyls. Chemosphere, 34(12): 2595-2600
Lans, M.C., Klasson-Wehler, E., Willemsen, M., Meussen, E., Safe, S., Brouwer, A. (1993) Structure-dependent, competitive interaction of hydroxy-polychlorobiphenyls, -dibenzo-p-dioxins and -dibenzofurans with human transthyretin. Chemico-Biological Interactions, 88(1): 7-21
Larson, S.D., Jackson, L.N., Riall, T.S., Uchida, T., Thomas, R.P., Qiu, S., Evers, B. M. (2007) Increased Incidence of Well-Differentiated Thyroid Cancer Associated with Hashimoto Thyroiditis and the Role of the PI3k/Akt Pathway. Journal of the American College of Surgeons, 204(5): 764-773
Lavado-Autric, R., Ausó, E., García-Velasco, J.V., Arufe, M.del C., del Rey, F.E., Berbel, P., de Escobar, G.M. (2003) Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny. Journal of Clinical Investigation, 111(7): 1073-1082
Mijatović, V., Samojlik, I., Petković, S., Horvat, O., Tomić, Z., Sabo, A. (2014) Hormonal contraception: Habits and awareness female students of the University of Novi Sad, Vojvodina, Serbia. Medicinski pregled, vol. 67, br. 9-10, str. 290-296
Miller, A.C., Stewart, M., Brooks, K., She, L., Page, N. (2002) Depleted uranium-catalyzed oxidative DNA damage: absence of significant alpha particle decay. Journal of Inorganic Biochemistry, 91(1): 246
Mohandy, R., Patnaik, S., Ramani, B. (2014) Subclinical hypothyroidis during pregnancy: A clinical review. Ind J Clin Pract, 25(5): 449-54
Ostroumova, E., Brenner, A., Oliynyk, V., Mcconnell, R., Robbins, J., Terekhova, G., i dr. (2009) Subclinical hypothyroidism after radioiodine exposure: Ukrainian-American cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident (1998-2000). Environ Health Perspect, 117(5):745-50
Petersen, K., Lindstedt, G., Lundberg, P.-A., Bengtsson, C., Lapidus, L., Nyström, E. (1991) Thyroid disease in middle-aged and elderly Swedish women: thyroid-related hormones, thyroid dysfunction and goitre in relation to age and smoking. Journal of Internal Medicine, 229(5): 407-413
Sabo, A., Stanulovi?, M., Jakovljevic, V., Grujic, Z. (2001) Collaborative study on drug use in pregnancy: the results of the follow-up 10 years after (Novi Sad Centre). Pharmacoepidemiology and Drug Safety, 10(3): 229-235
Sarap, N.B., Janković, M.M., Todorović, D.J., Nikolić, J.D., Kovačević, M.S. (2014) Environmental radioactivity in southern Serbia at locations where depleted uranium was used. Arh Hig Rada Toksikol, 65(2): 189-97
Schuur, A. G., Boekhorst, F.M., Brouwer, A., Visser, T.J. (1997) Extrathyroidal Effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Thyroid Hormone Turnover in Male Sprague-Dawley Rats1. Endocrinology, 138(9): 3727-3734
Škrbić, B., Đurišić-Mladenović, N. (2005) Izvori polihlorovanih bifenila u atmosferu. Gas, vol. 10, br. 4, str. 15-23
Škrbić, B.D., Miljević, N. (2002) An evaluation of residues at an oil refinery site following fires. Journal Of Environmental Science and Health Part A-Toxic/Hazardous Substances & Environmental Engineering, vol. 37, br. 6, str. 1029-1039
Takser, L., Mergler, D., Baldwin, M., de Grosbois, S., Smargiassi, A., Lafond, J. (2005) Thyroid Hormones in Pregnancy in Relation to Environmental Exposure to Organochlorine Compounds and Mercury. Environmental Health Perspectives, 113(8): 1039-1045
Tronko, M.D., Brenner, A.V., Olijnyk, V.A., Robbins, J., Epstein, O.V., McConnell, R.J., Bogdanova, T.I., Fink, D.J., Likhtarev, I.A., Lubin, J.H. (2006) Autoimmune Thyroiditis and Exposure to Iodine 131 in the Ukrainian Cohort Study of Thyroid Cancer and Other Thyroid Diseases after the Chornobyl Accident: Results from the First Screening Cycle (1998-2000). Journal of Clinical Endocrinology & Metabolism, 91(11): 4344-4351
Tunbridge, W.M., Caldwell, G. (1991) The epidemiology of thyroid diseases. u: Braverman L.E., Utiger R.D. [ur.] The Thyroid: A fundamental and Clinical Text, Philadelphia: Lippincot
Vanderpump, M.P. (2007) Should we treat mild subclinical/mild hyperthyroidism?. J Clin Endocrinol Metab, No. 92(8 Suppl):S1-47
Vial, T., Nicolas, B., Descotes, J. (1996) Clinical immunotoxicity of pesticides. Journal of Toxicology and Environmental Health, 48(3): 215-229
Vreugdenhil, H.J.I., Mulder, P.G.H., Emmen, H.H., Weisglas-Kuperus, N. (2004) Effects of Perinatal Exposure to PCBs on Neuropsychological Functions in the Rotterdam Cohort at 9 Years of Age. Neuropsychology, 18(1): 185-193
Wan, B., Fleming, J.T., Schultz, T.W., Sayler, G.S. (2006) In vitro immune toxicity of depleted uranium: Effects on murine macrophages, CD4+ T cells, and gene expression profiles. Environ Health Perspect, 114(1): 85-91
 

O članku

jezik rada: engleski
vrsta rada: izvorni naučni članak
DOI: 10.2298/MPNS1602011H
objavljen u SCIndeksu: 27.02.2016.