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Acta medica Medianae
2019, vol. 58, br. 3, str. 102-110
jezik rada: engleski
vrsta rada: pregledni članak
objavljeno: 16/11/2019
doi: 10.5633/amm.2019.0315
Creative Commons License 4.0
Tumori paratiroidnih žlezda
Klinički centar Niš, Klinika za endokrinologiju, dijabetes i bolesti metabolizma

e-adresa: saskavalenta@sezampro.rs

Sažetak

Paratiroidne žlezde su male endokrine žlezde u vratu čoveka koje sekretuju paratiroidni hormon ili parathormon (PTH), koji zajedno sa kalcitoninom i D-vitaminom ima primarnu ulogu u regulaciji koncentracije kalcijuma i fosfata u organizmu. Najčešće oboljenje paratiroidnih žlezda predstavlja povećano i nekontrolisano lučenje PTH koje se može definisati kao primarni hiperparatiroidizam, ako nastaje kao posledica pojačane funkcije jedne ili više paratiroidnih žlezdi ili kao sekundarni hiperparatiroidizam koji se javlja najviše u hroničnoj bubrežnoj insuficijenciji ili kao posledica deficita vitamina D. Karcinom paratiroidnih žlezdi je veoma retko oboljenje i predstavlja najređi maligni endokrini tumor. Učestalost karcinoma kod bolesnika sa primarnim hiperparatiroidizmom je manja od 1%. Intraoperativno prepoznavanje ovog tumora od strane hirurga i adekvatna resekcija sa odstranjivanjem primarne lezije, uz patohistološku verifikaciju su najbolji tretman za bolesnike sa ovom primarnom lezijom.

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