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Vojnosanitetski pregled
2018, vol. 75, br. 3, str. 320-325
jezik rada: engleski
vrsta rada: prikaz slučaja
doi:10.2298/VSP160512237P

Creative Commons License 4.0
Maligni fibrozni histiocitom desne natkolenice
aClinical Center Kragujevac, Clinic for General and Thoracic Surgery, Kragujevac + University of Kragujevac, Faculty of Medical Sciences, Kragujevac
bMilitary Medical Academy, Clinic for General Surgery, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade
cClinical Center Kragujevac, Department of Pathology, Kragujevac
dUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + University of Kragujevac, Department of Anatomy, Kragujevac
eUniverzitet u Kragujevcu, Medicinski fakultet
fUniversity of Kragujevac, Faculty of Medical Sciences, Kragujevac + Clinical Center Kragujevac, Department of Anesthesiology and Reanimatology, Kragujevac

e-adresa: maja@medf.kg.ac.rs

Projekat

Primena biomedicinskog inženjeringa u pretkliničkoj i kliničkoj praksi (MPNTR - 41007)
Preklinička ispitivanja bioaktivnih supstanci (MPNTR - 41010)

Sažetak

Uvod. Maligni fibrozni histiocitom je pleomorfni sarkom visokog malignog potencijala koji se brzo širi. Karakteriše se širenjem lokalnom invazijom i ranom pojavom udaljenih metastaza. Najčešće lokalizacije su ekstremiteti, trup i retroperitoneum. S obzirom na redak preparat, nedovoljno jasnu etiologiju i mehanizme nastanka ove bolesti, kao i adekvatan patohistološki nalaz i intraoperativni prikaz, cilj ovog prikaza je bio da se ukaže na trenutna saznanja o ovoj bolesti, njenoj etiologiji, patohistološkim karakteristikama, diferencijalnoj dijagnozi i lečenju. Prikaz bolesnika. Prikazana je bolesnica, stara 56 godina, sa tumorom desne natkolenice koji se klinički prezentovao kao inkapsulirani hematom. Kompjuterizo-vanom tomografijom utvrđeno je da se radilo o intramuskularnom tumoru koji se komprimovao u okolne strukture. Ex tempore biopsija je ukazala na maligni potencijal tumora. Urađena je široka i radikalna ekscizija promene, a definitivni patohistološki nalaz pokazao je da se radilo o malignom fibroznom histiocitomu. Zaključak. Maligni fibrozni histiocitom predstavlja najčešći tip sarkoma mekih tkiva kod odraslih. Često je lokalizovan na donjim ekstremitetima. Svaki brzorastući tumefakt mekih tkiva donjih ekstremiteta, koji na snimku kompjuterizovane tomografije podseća na inkapsulirani hematom sa zonama nekroze, treba da pobudi sumnju na maligni fibrozni histiocitom.

Ključne reči

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