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Acta Facultatis Medicae Naissensis
2009, vol. 26, br. 4, str. 181-185
jezik rada: engleski
vrsta rada: izvorni naučni članak
Veličina i broj argirofilnih nukleolarnih organizatora i stopa preživljavanja bolesnika sa intraoralnim karcinomima
aMedicinski fakultet, Odeljenje za maksilofacijalnu hirurgiju, Niš
bMedicinski fakultet, Institut za patologiju, Niš
cMedicinski fakultet, Institut za radiologiju, Niš

e-adresa: pesic.z@gmail.com

Sažetak

Određivanje budućeg kliničkog toka karcinoma predstavlja objekat brojnih istraživanja koji za predmet imaju uticaj brojnih kliničkih i histopatoloških nalaza na klinički tok tumora. Vrednosti argirofilnih nukleolarnih organizatora (AgNOR-a) predstavljaju jednu od njih. Odnos njihovog broja i veličine spram kliničkih parametara bio je predmet brojnih istraživanja na različitim tumorima kao i na različitim lokacijama na ljudskom organizmu. Cilj istraživanja bio je odrediti značaj vrednosti broja i veličine AgNOR-a u odnosu na kliničko ponašanje intraoralnih karcinoma, posmatrano kroz dužinu preživljavanja bolesnika. Veličina i broj AgNOR-a je analizirana u tumorskom materijalu 50 bolesnika sa intraoralnim karcinomima sa različitim periodima postterapeutskog preživljavanja. Regresionom analizom korelacija između broja i veličine AgNOR-a i dužine preživljavanja kod bolesnika sa intraoralnim karcinomima nije konstatovana. Spram dobijenih rezultata, može se reći da vrednosti broja i veličine AgNOR-a, kod intraoralnih karcinoma ne koreliraju.

Ključne reči

karcinomi; intraoralni; AgNOR

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