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Acta Facultatis Medicae Naissensis
2009, vol. 26, iss. 4, pp. 181-185
article language: English
document type: Original Scientific Paper
published on: 25/05/2010
Size and number of silver-stained nucleolar organizer regions and survival rate in patients with intraoral carcinomas
aUniveristy of Niš, Faculty of Medicine, Department of Maxillofacial and Oral Surgery
bUniveristy of Niš, Faculty of Medicine, Department of Pathology
cUniveristy of Niš, Faculty of Medicine, Institute of Radiology



Determination of future clinical behavior of carcinomas still present the subject of numerous investigations in which different clinical and histopathological findings have been analyzed. The value of argyrophilic nucleolar organizers (AgNOR) is one of them, and the association between their number and size and clinical findings have been analyzed in numerous investigations, on different tumors and different locations in the human body. The aim of this investigation was to determinate the value of number and size of AgNOR in predicting the clinical behavior of intraoral carcinomas throughout survival rate of patients. The AgNOR size and number were analyzed in 50 patients with intraoral squamous cell carcinomas with different survival rates. By regression analysis, the relationship between AgNOR size and number and survival rate was not found. According to our results, it can be said that the values of AgNOR size and number in patients with intraoral carcinomas are not in correlation with survival rate.



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