Differences in quality of life between patients with severe hip and knee osteoarthritis

Jandrić, Slavica

doi:10.2298/VSP150502317J

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Vojnosanitetski pregled

2018, vol. 75, br. 1, str. 62-67

Razlike u kvalitetu života između pacijenata sa teškom artrozom kuka i kolena

Jandrić Slavica

Univerzitet u Banjoj Luci, Medicinski fakultet, Republika Srpska, BiH

e-adresa: slavajandric@yahoo.com

Ključne reči: osteoartritis; kuk; koleno; kvalitet života

Sažetak

Uvod/Cilj. Osteoartritis je klinička manifestacija degenerativnih promena u zglobu. Cilj ove studije je bio da se istraži postojanje razlika u kvalitetu života (QoL) između bolesnika sa teškom artrozom (OA) kuka i kolena. Metode. Studijom preseka obuhvaćeno je 195 bolesnika (prosečne starosti 63.2 ± 11.1 godina) sa dijagnozom artroze kuka ili kolena, kojima je bila indikovana totalna artroplastika kuka ili kolena. Bolesnici su podeljeni u tri grupe u odnosu na lokalizaciju artroze. Prvu grupu su činili bolesnici sa artrozom kuka, drugu sa artrozom kolena i treću sa artrozom i kuka i kolena zajedno. Za svakog bolesnika smo beležili demografske i kliničke podatke. Kvalitet života ovih bolesnika merili smo pomoću Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) upitnika. Za statističku značajnost razlika uzimali smo nivo od p < 0.05. Rezultati. Najbolji QoL je bio u grupi bolesnika sa OA kolena (42.7 ± 11.3), a najlošiji u grupi bolesnika sa OA kuka i kolena zajedno (35.8 ± 12.7). QoL procenjen WOMAC skorom je bio značajno različit između tri grupe bolesnika sa artrozom (F = 5.377, p < 0.01), kao i domen fizičke funkcije (F = 5.273, p < 0.01). Rezultati tri modela multiple linerane regresije gde je WOMAC skor zavisna varijabla, a godine starosti, indeks telesne mase (BMI), socijalni status, bol, ukočenost, fizička funkcija, arterijska hipertenzija, miokardiopatija, dijabetes melitus nezavisne varijable, pokazali su da je QoL procenjen WOMAC skorom statistički značajno udružen sa bolom i fizičkom funkcijom u prvoj (OA kuka) i drugoj (OA koljena) grupi bolesnika, dok je u trećoj grupi bolesnika (sa OA kuka i koljena zajedno), WOMAC skor bio udružen sa BMI, bolom, fizičkom funkcijom i dijabetes melitusom. Zaključak. Kod bolesnika sa teškom OA kuka i kolena, QoL je, u odnosu na lokalizaciju, bio značajno različit. Bol i fizička funkcija su značajno udruženi sa QoL bolesnika sa teškom OA kuka i kolena. U grupi bolesnika sa OA kuka i kolena zajedno, QoL je bio značajno udružen i sa BMI i dijabetesom melitusom.

Abstract

Background/Aim. Osteoarthritis (OA) is the clinical manifestation of degenerative joint changes. The aim of this study was to investigate differences in quality of life (QoL) between patients with severe hip and knee OA. Methods. This is the cross-sectional study of 195 patients (average age 63.2 ± 11.1 yrs), with a diagnosis of OA of the hip and knee that were assigned to receive a total hip or knee replacement. The patients were divided into three groups in relation to localization of OA. The first group included patients with hip OA; the second group consisted of patients with knee OA and the third group with both hip and knee OA. Demographic and clinical data were collected for each patient. We measured health-related quality of life (QoL) by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaires. Statistical significance of differences was at the level of p < 0.05. Results. The best QoL was in the group of knee OA (42.7 ± 11.3) and the worst in the group with both hip and knee OA patients (35.8 ± 12.7). QoL assessed by WOMAC score and the domain of physical function were significantly different among three groups of patients with OA (F = 5.377, p < 0.01 and F = 5.273, p < 0.01) respectively). Results of three multiple linear regression models where WOMAC score was dependent variable and age, body mass index (BMI), social class, pain, stiffness, physical function, hypertension, cardiomyopathy, diabetes mellitus were independent variables, have shown that QoL was statistically significantly associated with pain and physical function in the hip and knee OA groups, whereas in the group with both hip and knee OA patients, QoL was associated with BMI, pain, physical function and diabetes mellitus. Conclusion. QoL of patients with severe hip and knee osteoarthritis in relation to localization was significantly different. QoL in severe hip and knee OA patients was significantly associated with pain and physical function, but in patients with both hip and knee OA QoL was also associated with BMI and diabetes mellitus.

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O članku

jezik rada: engleski
vrsta rada: izvorni naučni članak
DOI: 10.2298/VSP150502317J
objavljen u SCIndeksu: 26.01.2018.
metod recenzije: dvostruko anoniman

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